/A RSS feed provided by Umeå Universityen-usFri, 12 Dec 2025 22:53:47 +0100/en/news/eu-funding-secures-continued-research-on-chlamydia_12152269/The European Research Fund (ERC) provides secured funding for five years with the consolidator grant to Barbara Sixt's research at Umeå University on chlamydia.Thu, 11 Dec 2025 12:02:42 +0100<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/fe7dad3d06be4b8e913905244909f829/sixt_barbara_8877_180426_mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/fe7dad3d06be4b8e913905244909f829/sixt_barbara_8877_180426_mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/fe7dad3d06be4b8e913905244909f829/sixt_barbara_8877_180426_mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/fe7dad3d06be4b8e913905244909f829/sixt_barbara_8877_180426_mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/fe7dad3d06be4b8e913905244909f829/sixt_barbara_8877_180426_mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/fe7dad3d06be4b8e913905244909f829/sixt_barbara_8877_180426_mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Barbara Sixt, Department of Molecular Biology and Group Leader at The Laboratory for Molecular Infection Medicine Sweden (MIMS)&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>Barbara Sixt is research group leader at MIMS, Molecular Infection Medicine Sweden and resarcher at det Department of Molecular Biology.</p><p>Chlamydia is the most common bacterial sexually transmitted infection. Each year, more than 25,000 people in Sweden and around 130 million worldwide contract the disease. While symptoms are often mild, chlamydia can have serious consequences. It may cause infertility, chronic pain, complications during pregnancy, and even increase the risk of cervical and ovarian cancers.</p><p>Today, chlamydia is treated with antibiotics, which kill the bacteria and help the body recover. However, most antibiotics have a broad spectrum of activity. This means they attack not only harmful bacteria but also beneficial ones, such as those in our gut that support digestion. This can lead to side effects. Broad-spectrum antibiotics also accelerate the rise of antibiotic resistance &ndash; a global health threat that makes infections harder to treat and even puts routine procedures like surgery or cancer therapy at risk.</p><p>There is another challenge: the bacterium that causes chlamydia can alter the biology of our cells. Current antibiotics eliminate the bacteria but not these altered cells, which may contribute to the long-term complications mentioned above.</p><p>To overcome these problems, Barbara Sixt&rsquo;s research group at Ume&aring; University is exploring new strategies to treat chlamydia more selectively. In our current project, funded by the European Research Council. They focus on the bacterium&rsquo;s unique growth niche inside human cells &ndash; a compartment called the &ldquo;inclusion.&rdquo; When the bacterium causing chlamydia infects a person, it enters their cells and hides within this inclusion to escape the cell&rsquo;s defense systems. These defenses would normally destroy the invader or even trigger &ldquo;cellular suicide&rdquo; &ndash; the deliberate death of the infected cell &ndash; to stop the infection.</p><p>The research group&rsquo;s goal is to understand how the bacterium maintains the integrity of this protective inclusion. By uncovering these mechanisms, we hope to find ways to destabilize the inclusion, allowing our cell&rsquo;s natural defenses to fight back. The researchers also aim to learn how to steer the process toward cellular suicide &ndash; a strategy that could eliminate both the bacterium and the manipulated cells.</p><p>Ultimately, this research will lay the foundation for innovative treatments that are more sustainable than traditional antibiotics and could also help combat other disease-causing microbes that use similar growth niches.</p><p>The ERC Consolidator Grant is selected by the European Research Council (ERC), which is linked to the European Commission. This means five years of secured funding of up to two million euros. Researchers with 7-12 years of experience since completing their PhD, a scientific track record showing great promise, and an excellent research proposal may be granted the grant.</p><p>&nbsp;</p>/en/news/eu-funding-secures-continued-research-on-chlamydia_12152269//en/news/the-arctic-six-strengthens-research-at-umea-university_12152698/In 2022, The Arctic Six introduced a new two-year fellowship programme for mid-to-senior career researchers to develop new collaborations in the Nordic region. Through the Chairs Programme, researchers from the alliance of six universities received support to create new networks and projects, further strengthening the Arctic research environment.Mon, 08 Dec 2025 08:00:09 +0100<p class="quote-center">The Arctic Six is a strategically important part of Ume&aring; University&rsquo;s work to advance research and education in the Arctic.</p><h2 id="info0" data-magellan-target="info0">A strategic platform in the North</h2><p>The Arctic Six is a collaboration between six northern universities working together to strengthen research, education and cooperation across the Arctic. Through initiatives such as the Chairs Programme, the alliance has deepened academic exchange and laid the foundation for new projects and partnerships. In doing so, the collaboration has reinforced Ume&aring; University&rsquo;s position internationally and strengthened opportunities for continued joint development.</p><p>The two-year Arctic Six Chairs fellowship (2022&ndash;2024) saw fourteen research leaders organise more than sixty workshops and participate in over one hundred meetings. They collaborated to submit fifty-eight joint research proposals and together secured approximately &euro; 35 million in external funding. Each euro invested in the programme has generated more than thirty euros in new funding &ndash; demonstrating the programme&rsquo;s leverage effect.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="2b49e637-e98b-46c8-a930-fcaebdb81e42" data-contentname="Cathrine Norberg">{}</div><p>Cathrine Norberg, Deputy Vice-Chancellor, emphasises:<br>&ldquo;The Arctic Six is a strategically important part of Ume&aring; University&rsquo;s work to advance research and education in the Arctic. The Chairs Programme demonstrates how long-term collaboration can foster academic cooperation and enhance our international presence. It helps us create the conditions for new knowledge that benefits the region and the wider Arctic community.&rdquo;</p><h2 id="info1" data-magellan-target="info1">Results that point the way forward</h2><p>The Chairs Programme has led to significant scientific achievements and established a growing framework for collaboration in Arctic health, education, tourism, Indigenous studies, and governance. In addition, several participants have developed joint courses, publications and long-term partnerships that continue to strengthen northern cooperation.</p><p>&ldquo;For researchers at Ume&aring; University, the Arctic Six Chairs has opened new paths for international collaboration and external funding. The initiative has made it possible to pursue larger and interdisciplinary projects, which in turn enhances research quality and the university&rsquo;s Arctic profile,&rdquo; says Keith Larson, Director of the Arctic Centre.</p><h2 id="info2" data-magellan-target="info2">From experience to development</h2><p>The Arctic Centre has played a key role in coordinating Ume&aring; University&rsquo;s engagement within Arctic Six and in increasing the university&rsquo;s visibility in the northern research landscape. By creating connections between researchers, faculties and leadership, the Centre has strengthened internal collaboration and strategic presence within the network.</p><p class="quote-center">The first round of Arctic Six Chairs shows that northern collaboration is not only possible &ndash; it is powerful.</p><p>The evaluation now points to the next steps &ndash; clearer support structures and more targeted communication &ndash; elements that together provide the foundation for the next phase of development.</p><p>&ldquo;The first round of Arctic Six Chairs shows that northern collaboration is not only possible &ndash; it is powerful. We are now building on these experiences to develop the next phase with a stronger structure and continued focus on supporting our researchers,&rdquo; says Johanne Raade, Director of The Arctic Six.</p><p>Through the work within The Arctic Six, it has become clear how international collaboration can be translated into tangible outcomes &ndash; for researchers and the university. The experiences gained through the Chairs Programme highlight the value of long-term structures, shared learning and mutual trust &ndash; factors that now shape the foundation for the continued development of the collaboration.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="76c32add-c398-4dcd-a846-740a690fd5be" data-contentname="Hans Pettersson">{}</div><p>Hans Pettersson served as an Arctic Six Chair (2022&ndash;2024) and reflects:</p><p>&ldquo;During my time as Chair of The Arctic Six, what struck me most was how quickly genuine collaboration emerges once researchers have the chance to meet regularly. Trust grows, ideas take shape, and suddenly you&rsquo;re working together on a proposal none of you could have created alone. That&rsquo;s the real strength of the Chairs Programme &ndash; it gives us the time and continuity to turn shared ideas into something substantial.&rdquo;</p><p>With approximately 41,500 students and 4,600 employees, Ume&aring; University is the largest Arctic university in the Nordic region and one of the most productive universities globally in Arctic research. Through The Arctic Six and initiatives such as the Chairs Programme, the university continues to deepen its role as a driving force in international collaboration and to strengthen the conditions for new knowledge about and for the Arctic.</p>/en/news/the-arctic-six-strengthens-research-at-umea-university_12152698//en/news/three-umea-researchers-appointed-wallenberg-academy-fellows_12152121/Infection researcher Anne-Marie Fors Connolly has been awarded SEK 500,000 in investment funding from the ALF Committee to continue developing a national database infrastructure that will enable more researchers to study critical infectious diseases.Fri, 28 Nov 2025 08:30:56 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/a61943d648404a81a13a412f8f8c3c39/fors_conolly_anne-marie_9869_220405_hkn4.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/a61943d648404a81a13a412f8f8c3c39/fors_conolly_anne-marie_9869_220405_hkn4.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/a61943d648404a81a13a412f8f8c3c39/fors_conolly_anne-marie_9869_220405_hkn4.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/a61943d648404a81a13a412f8f8c3c39/fors_conolly_anne-marie_9869_220405_hkn4.jpg?mode=crop&amp;width=640 640w, /contentassets/a61943d648404a81a13a412f8f8c3c39/fors_conolly_anne-marie_9869_220405_hkn4.jpg?mode=crop&amp;width=854 854w, /contentassets/a61943d648404a81a13a412f8f8c3c39/fors_conolly_anne-marie_9869_220405_hkn4.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Anne-Marie Fors Connolly investigates both acute and long-term complications after infections by analyzing whole population data.</p><span class="bildPhotografer"><span class="photo">Image</span>Hans Karlsson</span></div></div><p class="quote-center">I hope more research groups will recognize the importance of studying how infections affect public health</p><p>&ldquo;Improving patient care is what drives me,&rdquo; says Anne-Marie Fors Connolly, specialist physician and associate professor at the Department of Clinical Microbiology, Ume&aring; University.</p><p>The research infrastructure Critical Microbes integrates test results from clinical microbiology laboratories with outcomes of infectious diseases across Sweden. By collecting and coordinating population-wide data, including socioeconomic, demographic, and clinical variables, it becomes possible to map how infectious diseases impact public health, work capacity, and societal costs.</p><p>&ldquo;It is an interdisciplinary effort that combines advanced statistical methods with clinical expertise to identify risk factors, optimize treatment strategies, and generate robust, evidence-based knowledge,&rdquo; Anne-Marie Fors Connolly explains.</p><h2 id="info0" data-magellan-target="info0">Patient centred improvement in focus</h2><p>The idea for the infrastructure came from Denmark, where all test results are centralized in real time in a surveillance database. This makes it possible to monitor how infections affect the country.</p><p>&ldquo;In Sweden, we do not have the same capability, as only positive results for notifiable infections are centralized. I want to create an infrastructure where test results from all clinical microbiology laboratories in Sweden are historically collected. These will be linked to the population database already maintained by my research group, creating a connection between infection test results and patient outcomes across the entire population,&rdquo; says Anne-Marie Fors Connolly.</p><p>Other research groups with ethically approved projects will be able to request data for their studies. This will make it possible to conduct research on critical infectious diseases for many years to come.</p><p>&ldquo;I hope more research groups will recognize the importance of studying how infections affect public health. It is a crucial foundation for designing targeted preventive measures and improving patient care,&rdquo; Anne-Marie Fors Connolly adds.</p><h2 id="info1" data-magellan-target="info1">Learning from Denmark</h2><p>The investment funds will enable continued development of Critical Microbes. Anne-Marie Fors Connolly will also visit the Statens Serum Institut in Denmark to learn from their experience.</p><p>&ldquo;It is the only place in the world with such an infection database, so their insights are extremely valuable.&rdquo;</p><p>Critical Microbes is also supported by <a href="https://www.scilifelab.se/news/four-collaborative-projects-selected-in-the-rdcp-call/" target="_blank" rel="noopener">SciLifeLab/RDCP</a> with SEK 1 million and <a href="https://www.scilifelab.se/strategic-areas/pandemic-laboratory-preparedness/" target="_blank" rel="noopener">Pandemic Laboratory Preparedness</a> with SEK 1.98 million.</p>/en/news/critical-microbes-building-a-national-infection-research-infrastructure-inspired-by-denmark_12151786//en/news/new-influenza-variant-could-make-the-winter-season-extra-demanding_12151119/A new influenza strain, the K variant, is spreading across Europe and detected in Sweden. It is a subtype of influenza A (H3N2) and raises concern as it causes more severe symptoms and spreads faster than previous strains. This year’s flu vaccine is not fully adapted to protect against it, according to the Public Health Agency of Sweden and the European Centre for Disease Prevention and Control.Fri, 21 Nov 2025 13:56:15 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/c566c9478ff0441692f493015c7fc3cd/arnberg_niklas_3979_210922_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c566c9478ff0441692f493015c7fc3cd/arnberg_niklas_3979_210922_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c566c9478ff0441692f493015c7fc3cd/arnberg_niklas_3979_210922_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c566c9478ff0441692f493015c7fc3cd/arnberg_niklas_3979_210922_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/c566c9478ff0441692f493015c7fc3cd/arnberg_niklas_3979_210922_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/c566c9478ff0441692f493015c7fc3cd/arnberg_niklas_3979_210922_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Niklas Arnberg, professor at the Department of Clinical Microbiology at Ume&aring; university, says the K variant makes it especially important this year for older adults and people in risk groups to get vaccinated ahead of the flu season.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">there is extra reason to get vaccinated this year</p><p>&ldquo;Symptoms resemble classic influenza with high fever, chills, headache, dry cough, and muscle pain, but they may be more pronounced with this variant,&rdquo; Niklas Arnberg explains.</p><p>The K variant has been linked to an early start of the flu season in several countries, and experts warn that this season could be tougher than usual. Although the vaccine offers less protection against infection with the K variant, Arnberg emphasizes that vaccination remains important:&nbsp;</p><p>&ldquo;The vaccine likely provides somewhat weaker protection against the K variant than we would like, but it is by no means ineffective. It also protects against other circulating influenza strains and reduces the risk of severe illness, which is particularly important for older adults and those in risk groups.&rdquo;</p><p>To reduce transmission, good hand hygiene, sneezing into your elbow, and avoiding close contact with elderly or vulnerable individuals when symptomatic are recommended. However, Niklas Arnberg does not believe society will need to impose restrictions or other measures.&nbsp;</p><p>&ldquo;But I do think there is extra reason to get vaccinated this year, thus more reason than in previous years,&rdquo; he adds.</p>/en/news/new-influenza-variant-could-make-the-winter-season-extra-demanding_12151119//en/news/kbc-days-2025-bridges-disciplines_12150919/Last week, the annual conference organised by Chemical Biological Centre (KBC) at Umeå University and SLU, gathered over 360 participants for two intensive days of knowledge exchange, networking, and celebrating the year’s achievements. This year’s theme, “Bridging Scales: from Quantum to Cosmos”, united discussions on how advances in physics, chemistry, life and Earth and planetary sciences can intersect to address fundamental questions about matter, life, and the universe.Tue, 02 Dec 2025 18:38:10 +0100<p>Since 2009, the KBC DAYS conference has offered a platform for knowledge exchange among researchers from different departments and disciplines, while also highlighting research achievements, awards, and new faculty members within the KBC community.</p><p><em>&ldquo;I wasn&rsquo;t sure I would understand the different topics in the programme, but the speakers did a wonderful job communicating their science, and I found myself engaged in every talk throughout both days &mdash; it was all very interesting&rdquo;</em>, says Edoardo Piombo from Ume&aring; Plant Science Centre. He was one of the attendees at the KBC DAYS 2025 who enjoyed the event&rsquo;s strong multidisciplinary atmosphere.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_opening.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_opening.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_opening.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_opening.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_opening.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_opening.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>This year's main scientific theme was "Bridging Scales: from Quantum to Cosmos," serving as a central focus for discussions on different scales of scientific research and on analysing and applying research findings across various scales and dimensions. The choice of this theme was also influenced by the International Year of Quantum Science and Technology (IYQ 2025). In this photo, Lars-Anders Carlson and Stefan Bj&ouml;rklund, both members of the scientific organising committee, are opening the conference in the Carl Kempe lecture hall at KBC.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><h3><strong>The multidisciplinary programme highlights</strong></h3><p>Within the theme &ldquo;Bridging Scales: from Quantum to Cosmos&rdquo;, the invited keynote speakers showcased cutting-edge research spanning across the scales from quantum biology to remote sensing and machine learning in landscape analysis, and to comparative planetology.</p><p>At the far end of the spectrum, Clarice D. Aiello, a leading expert in quantum biology, reviewed experimental evidence for quantum phenomena in biological systems, discussed proposed biophysical mechanisms, and highlighted their potential implications for technology, therapeutics, and our understanding of life across scales.</p><p>Reflecting on her talk, Assistant Professor Nicol&ograve; Maccaferri, a member of the scientific organising committee, commented:</p><p><em>&ldquo;Clarice&rsquo;s research at the intersection of physics and biology aims to confirm or refute the &lsquo;Quantum Biology Hypothesis&rsquo;, which suggests quantum states last long enough inside cells to be biologically relevant. If proven true, this way of approaching biology and biological problems could revolutionise our way of seeing and understanding life as we know it.&rdquo;</em></p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_clarice_aiello.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_clarice_aiello.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_clarice_aiello.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_clarice_aiello.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_clarice_aiello.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_clarice_aiello.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Clarice D. Aiello, founder of the Quantum Biology Ecosystem and CSO of the Quantum Biology Institute, USA, is conversing with conference participants after her inspiring keynote lecture &ldquo;Quantum Biology: How nature might be optimized to harness quantum mechanics&rdquo;.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><p>At the other extreme of the presented scale, Stephanie Werner from the Centre for Planetary Habitability at the University of Oslo explored current methods for detecting exoplanets, their surprising diversity, and the challenges of defining and identifying Earth-like habitability across evolving planetary systems.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_stephanie_werner.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_stephanie_werner.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_stephanie_werner.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_stephanie_werner.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_stephanie_werner.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_stephanie_werner.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Professor Stephanie Werner, from the Department of Geosciences at the Centre for Planetary Habitability, University of Oslo, is delivering her keynote lecture titled "Exoplanets, near and far, small and rare, large and plenty?".</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><h3><strong>With a focus on young researchers</strong></h3><p>The KBC DAYS traditionally give PhD students a chance to present their projects through a short &ldquo;elevator talk&rdquo; and/or a poster to a broad, multidisciplinary scientific community, sharpening their science communication skills. The best talk, selected by the evaluation committee, was awarded a travel voucher sponsored by the Ume&aring;-based company Agrisera, while the best poster, as voted by the participants, received the prize from SciLifeLab Ume&aring;.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_talk_hanna_jerndal.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_talk_hanna_jerndal.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_talk_hanna_jerndal.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_talk_hanna_jerndal.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_talk_hanna_jerndal.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_talk_hanna_jerndal.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Hanna Jerndal, from the Department of Clinical Microbiology, receives the Agrisera award for her outstanding &ldquo;Elevator talk&rdquo; presentation at KBC DAYS 2025, titled &ldquo;Longitudinal Assessment of Tubular and Glomerular Kidney Function After COVID-19 &ndash; a prospective cohort study&rdquo;. In the photo, Hanna is with Joanna Porankiewicz-Asplund from Agrisera and Stefan Bj&ouml;rklund, scientific coordinator of KBC.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_poster_mingyu_liu.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_poster_mingyu_liu.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_poster_mingyu_liu.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_poster_mingyu_liu.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_poster_mingyu_liu.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_best_poster_mingyu_liu.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Mingyu Liu from the Department of Plant Physiology, Ume&aring; Plant Science Centre (UPSC) receives the prize for the best poster titled &ldquo;Light-dependent modulation of sustained quenching during overwintering in Pinus koraiensis seedlings&rdquo;.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><p>On the second day of the conference, a panel discussion organised by the Ume&aring; Postdoc Society drew significant interest from doctoral students and postdocs. The session focused on navigating the career journey from postdoctoral researcher to principal investigator (PI). The panel, composed of six young PIs, discussed key aspects of transitioning from postdoc to PI, including strategies for obtaining early-career funding, crafting competitive grant proposals, leveraging mentorship and institutional support, balancing research with grant writing, and maintaining resilience in the face of setbacks.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_ups_panel_discussion.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_ups_panel_discussion.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_ups_panel_discussion.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_ups_panel_discussion.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_ups_panel_discussion.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_ups_panel_discussion.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Panel discussion &ldquo;From Postdoc to PI: Winning Grants and Finding Your Path&rdquo; organised by Ume&aring; Postdoc Society (UPS) and moderated by Madhusree Mitra and Keshi Chung. The panel consisted of (left to right) Max Renner (Department of Chemistry and UCMR), Ryo Morimoto (Department of Molecular Biology and MIMS), Verena Kohler (Department of Molecular Biology), Laura Bacete (Department of Plant Physiology, UPSC), Paulina Wanrooji (Department of Medical Biochemistry and Biophysics), and Eric Capo (Department of Ecology, Environment and Geoscience).</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><p><em>&ldquo;I found the panel discussion very valuable, especially as a PhD student who hasn&rsquo;t yet secured a postdoctoral position but is already thinking about a future career as a principal investigator. Hearing from established PIs about the challenges they faced on their journey to becoming leaders in their fields was eye-opening&rdquo;</em>, says Dmytro Sokol, doctoral student from the Department of Chemistry.</p><p>Among many personal experiences shared and practical advice offered, the panel emphasised a message that resonated with many: don't get stuck after a grant proposal rejection, ask your peers for feedback, and keep trying! The panellists also discussed that it can be a steep learning curve for those unfamiliar with the local research culture, creating hidden barriers to funding access. They agreed that one of the important steps in transitioning to an early career is learning how your local research funding and research support systems operate.</p><p><em>&ldquo;Overall, the discussion was inspiring and helped clarify my thoughts on whether I want to pursue the path to becoming a PI. It provided practical tips, a clearer understanding of what lies ahead, and strengthened my determination to face the challenges of my future academic career&rdquo;</em>, says Dmytro Sokol.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_dmytro_sokol.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_dmytro_sokol.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_dmytro_sokol.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_dmytro_sokol.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_dmytro_sokol.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_dmytro_sokol.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Dmytro Sokol, a PhD student in biochemistry, is addressing the panel during the discussion &ldquo;From Postdoc to PI: Winning Grants and Finding Your Path&rdquo;.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><h3><strong>Journey across the scales with research infrastructures</strong></h3><p>The KBC DAYS also serves as a forum where research infrastructures at KBC and Campus Ume&aring; can showcase their advanced technologies, unique instruments, expert know-how, and services. These infrastructures can be used to explore different aspects of life- and material sciences, ranging from the atomic scale to entire ecosystems. For instance, mass spectrometry analyses performed by the Swedish Metabolomics Centre Ume&aring; (SMC) detect metabolites across a range from millimolar to femtomolar levels &mdash; over nine orders of magnitude. Meanwhile, the technical platforms at Ume&aring; Marine Sciences Centre (UMF) accommodate experiments from millilitres to litres of water in laboratory incubations, extending to multi-cubic-metre mesocosms, as well as field sampling throughout the Bothnian Sea. The temporal scale of experiments at UMF ranges from rapid molecular analyses within hours to seasonal and multi-year monitoring programmes that track environmental trends.</p><p>The impressive array of local and national research infrastructures available at KBC, SciLifeLab and &ldquo;on the other side of the road&rdquo;, at the Translational Research Centre at the University Hospital of Ume&aring;, was overviewed by Linda Sandblad, Ume&aring; Centre for Electron Microscopy and SciLifeLab Ume&aring;, and Ola Billing, from the Department of Diagnostics and Intervention.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_infrastructure_poster_session_umf.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_infrastructure_poster_session_umf.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_infrastructure_poster_session_umf.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_infrastructure_poster_session_umf.jpg?mode=crop&amp;width=640 640w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_infrastructure_poster_session_umf.jpg?mode=crop&amp;width=854 854w, /contentassets/585bc9a26ca2479d9443a94d7c46e0b4/kbc_days_2025_infrastructure_poster_session_umf.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Newcomers, as well as long-term KBC residents and other curious researchers, could meet infrastructure representatives at their posters to discuss potential projects, join guided tours of their facilities, or solve the infrastructure quiz. In the photo, Regina Kolzenburg and Mikael Peedu (in blue jumpers) talk to conference participants at their &ldquo;station&rdquo;, presenting the research facilities at the Ume&aring; Marine Sciences Centre (UMF).</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><h3><strong>Guinness World Records-worthy attempt to &ldquo;bridge scales&rdquo; from &Aring; to our solar system</strong></h3><p>One of the most memorable and exciting moments of the conference was the live experiment &ndash; creating the World&rsquo;s Smallest Solar System Model. During the Infrastructure session, participants could follow a live stream from the Ume&aring; Centre for Electron Microscopy (UCEM) lab, where staff scientist Nils Hauff created one of the model&rsquo;s elements, Saturn, inside FEI Scios, a Focused Ion Beam Scanning Electron Microscope. With a scale of 1 : 7 000 000 000 000, this model is so tiny that you would need a stereo microscope to find Saturn, which measures around 15 &mu;m or a pollen grain, and an electron microscope to see its moon Titan, which is about 700 nm in size. The entire solar system, including the Sun, planets, the most important moons, and dwarf planets such as Pluto, has been scaled down so much that 38 AU can fit onto a 75 cm-long metal rod.</p><p>Nils Hauff explained that the aim of this experiment was to demonstrate the instrument's capability to fabricate structures at the nanometer scale.</p><p><em>&ldquo;We also wanted to illustrate how extremely different length scales are involved in the research here at KBC and how challenging it is to comprehend those different length scales&rdquo;</em>, he says.</p><p>This academic stunt was inspired by the Sweden Solar System, the world's largest permanent scale model of the solar system, located throughout Sweden at a scale of 1:20 000 000, where the Sun is represented by Avicii Arena in Stockholm, and Ume&aring; holds the 13 cm-diameter model of dwarf planet Eris.</p><p><em>&ldquo;Now Sweden is home not only for the largest, but also for the smallest model of the solar system in the world!&rdquo;</em>, says Nils Hauff.</p><p>He already holds one record &ndash; earlier this year, he made the world&rsquo;s smallest Dala horse in collaboration with Erik Olof Wiklund, an artist and master&rsquo;s student at the Academy of Fine Arts. During the KBC DAYS, their photo &rdquo;The world's smallest Dalahorse&rdquo; won the KBC photo contest &ldquo;Bridging scales&rdquo; in a tough competition among nearly 30 other impressive artistic contributions.</p><h3><strong>Social element critical in bridging organisational boundaries</strong></h3><p>Throughout October, the KBC Ping-Pong tournament took place, attended by over 50 participants ranging from complete beginners to advanced players. Thanks to the energy and organisational skills of Irina Iakovleva, research coordinator at Bio4Energy, and several volunteers, the tournament became a much-appreciated event, providing a fantastic opportunity to enjoy sports and camaraderie with colleagues across KBC and beyond.</p><p>The tournament culminated with tense semi-finals and the final matches just before the conference dinner, adding excitement and an informal touch to the scientific gathering.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="a5a47b1d-ba16-4b68-89eb-efa709d3db0d" data-contentname="KBC Employee of the Year 2025">{}</div><p>During the conference dinner, the KBC Employee of the Year was announced. The winner was chosen by the KBC group members from several nominees who &ldquo;made a meaningful contribution to improving the work environment at KBC, especially by strengthening collaboration and community spirit&rdquo;. This year&rsquo;s award recipient was Sonali Ranade from UPSC. Sonali was nominated for her initiative in launching a laughter club, where colleagues gather to practise laughing yoga and breathing exercises, Pranayama, that help improve well-being and reduce stress. Dinner participants could try a brief introduction to the laughter session. The laughter club will resume regular sessions in spring 2026, and everyone interested is welcome to join.</p><p><em>&ldquo;Just come with the smile!&rdquo;</em> says Sonali Ranade, smiling.</p><p>The success of KBC DAYS 2025 was made possible through the collective efforts of a vibrant research community and the generous support of sponsors.</p><p>What new challenges will 2026 bring, and which scientific themes should we explore together within the interdisciplinary KBC research community? Get ready for the KBC DAYS 2026 and share your ideas for themes and other suggestions with the KBC Communications Office.</p><p><strong>More information:</strong></p><p><a href="~/link/e578cbc1f0ab444bae8e84840cae2a86.aspx">KBC Days 2025 programme and abstracts</a></p><p><a href="https://umeapostdocs.com/" target="_blank" rel="noopener">Homepage of Ume&aring; Postdoc Society</a></p><p><a href="https://www.swedensolarsystem.se/en/" target="_blank" rel="noopener">Sweden Solar System</a></p><p>UMU news: <a href="~/link/73ba2d62b3ac475ca5b4d713fe151f86.aspx">Art meets nanotechnology &ndash; the world&rsquo;s smallest Dala horse created at Ume&aring; University</a></p><p>UPSC news: <a href="https://www.upsc.se/about-upsc/news/6621-sonali-ranade-awarded-kbc-employee-of-the-year-2025.html" target="_blank" rel="noopener">Sonali Ranade awarded KBC Employee of the Year 2025&nbsp;</a></p><h2 id="info0" data-magellan-target="info0"><strong>KBC DAYS 2025 in Pictures</strong></h2>/en/news/kbc-days-2025-bridges-disciplines_12150919//en/news/two-nobel-symposia-at-umea-university-in-2026_12148986/A hormone produced in the thyroid gland can play a key role in the development of prostate cancer. This is shown in a new study by an international research group led by Umeå University, Sweden, and the Medical University of Vienna, Austria. By blocking a receptor for the hormone, the growth of tumour cells in the prostate was inhibited. In the long term, the discovery may open up a new way of attacking certain types of aggressive prostate cancer.Tue, 11 Nov 2025 10:01:38 +0100<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/3a6797bd21f447b6b4b555a56cc20209/lukas_kenner2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/3a6797bd21f447b6b4b555a56cc20209/lukas_kenner2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/3a6797bd21f447b6b4b555a56cc20209/lukas_kenner2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/3a6797bd21f447b6b4b555a56cc20209/lukas_kenner2.jpg?mode=crop&amp;width=640 640w, /contentassets/3a6797bd21f447b6b4b555a56cc20209/lukas_kenner2.jpg?mode=crop&amp;width=854 854w, /contentassets/3a6797bd21f447b6b4b555a56cc20209/lukas_kenner2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Lukas Kenner, visiting professor at the Department of Molecular Biology.<span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Medizinische Universit&auml;t Wien</span></p></div></div><p>"The results indicate that the receptor in question is a driving force in the growth of cancer. Substances that block it could thus be a target for future drugs against prostate cancer," says Lukas Kenner, visiting professor at Ume&aring; University and the one who has led the study that is published in Molecular Cancer.</p><p>The receptor in question is called thyroid hormone receptor Beta, TR&beta;. It binds the thyroid hormone triiodothyronine, T3. In laboratory experiments, the activation of T3 has led to a sharp increase in the number of prostate cancer cells. However, when the receptor TR&beta; was inhibited with the help of an active substance, NH-3, significantly reduced the growth of cancer cells. NH-3 is a substance that is only used in research to block TR&beta;.</p><p>The substance's effect on cancer was then confirmed in animal experiments in mice. Tumours treated with NH-3 remained smaller or progressed significantly more slowly. This was shown to be particularly effective in models of prostate cancer that are so-called castration resistant. This means that the tumour continues to grow despite treatment that reduces the amount of the male sex hormone testosterone, which usually drives cancer growth. This form is currently difficult to treat clinically.</p><p>Blocking TR&beta; using NH-3 worked by leading to the elimination of a particular signal, the androgen receptor signal, which is otherwise activated by testosterone and then plays a central role in the development of prostate cancer.</p><p>A review of data from cohorts of patients with prostate cancer supports these findings. In tissue samples, elevated levels of TR&beta; could be seen in tumours in the prostate compared to those in healthy tissue. In addition, genetic analyses show that mutations in many prostate cancer patients alter the signalling pathways for thyroid hormone. This suggests that blocking the thyroid hormone and its receptor may be a target for further research to find new treatments for prostate cancer.</p><p>"Of course, it is a balancing act not to change the hormonal balance in the thyroid gland more than necessary to fight cancer in another part of the body, and it will probably not be a solution for all types of prostate cancer. Further research will have to answer what a treatment could look like, possibly in combination with other treatments. Of course, this is an interesting track," says Lukas Kenner.</p><p>Prostate cancer is the most common form of cancer among men in Sweden and the second most common in the world. About one in ten Swedish men is affected by prostate cancer, about 2200 men a year die from the disease. When detected early, the disease is usually treated by reducing the amount of testosterone. However, many patients become resistant to this treatment, and as a result, the number of available treatments is limited.</p>/en/news/thyroid-gland-new-possible-target-for-prostate-cancer-treatment_12148877//en/news/the-representatives-fighting-for-a-better-work-environment_12147721/Work environment representatives play a key role in creating a safe and sustainable workplace. At the Department of Clinical Microbiology, Mikaela Lagerqvist, Carin Wibom and Ylva Hedberg Fransson must deal with everything from everyday challenges to complex situations – and they see that their work makes a difference.Fri, 31 Oct 2025 10:48:34 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9991-251020-mpn4.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9991-251020-mpn4.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9991-251020-mpn4.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9991-251020-mpn4.jpg?mode=crop&amp;width=640 640w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9991-251020-mpn4.jpg?mode=crop&amp;width=854 854w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9991-251020-mpn4.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ylva Hedberg Fransson, Mikaela Lagerqvist and Carin Wibom are work environment representatives at the Deaprtment of Clinical Microbiology at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">Work environment efforts need to be highlighted as a central and strategic part of the organization</p><p>&ldquo;Work environment efforts need to be highlighted as a central and strategic part of the organization &ndash; not something that happens alongside daily operations,&rdquo; says Mikaela Lagerqvist, laboratory assistant at the Department of Clinical Microbiology at Ume&aring; University.</p><p>In their roles as work environment representatives, Mikaela Lagerqvist, Carin Wibom, and Ylva Hedberg Fransson handle issues such as ergonomics, workplace calm, and environmental disruptions. Another common task is supporting employees in submitting reports via the IA system &ndash; a web-based tool for reporting work environment deviations. Their work often involves following up on these reports, for example by proposing corrective actions. All with the aim of preventing accidents and incidents.</p><p>&ldquo;For instance, we once received a report about broken hinges on four -80 &deg;C freezers, which posed a safety risk. This led to all the hinges being replaced before any accident occurred,&rdquo; says Ylva Hedberg, Associate professor&nbsp;at the Department of Clinical Microbiology at Ume&aring; University.</p><p>She continues:</p><p>&ldquo;We usually say we deal with &lsquo;Oops!&rsquo; and &lsquo;Ouch!&rsquo; &lsquo;Oops&rsquo; means it could have been dangerous but turned out fine, while &lsquo;Ouch&rsquo; is when an actual accident has happened. We learn from our mistakes &ndash; work environment efforts help us take action to prevent them from happening again.&rdquo;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9908-251020-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9908-251020-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9908-251020-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9908-251020-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9908-251020-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9908-251020-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Lessons learned from work environment work lead to change.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><h2 id="info0" data-magellan-target="info0">Positive changes</h2><p>When Ylva Hedberg Fransson first became a work environment representative about ten years ago, the role was relatively limited. Back then, the main activity was conducting an annual work environment inspection at the department.</p><p>Since Mikaela Lagerqvist and Carin Wibom joined as representatives in the spring of 2023, several positive changes have taken place. The trio has actively worked to highlight the importance of a healthy work environment, including through regular discussions and presentations at the department&rsquo;s workplace meetings. These meetings are now held in person instead of digitally via Teams, which has contributed to a better dialogue and increased engagement.</p><p>&ldquo;Since last year, we have been collaborating with HR and representatives for equal opportunities in a joint working group &ndash; the so called ALV group. Together, we address issues related to the work environment, equality, and discrimination, which has strengthened our efforts,&rdquo; says Mikaela Lagerqvist.</p><h2 id="info1" data-magellan-target="info1">Support &ndash; both physical and mental</h2><p>For Mikaela Lagerqvist, a good work environment means having the right conditions to do your job and feeling safe &ndash; both physically and mentally. She emphasizes the importance of a workplace climate that is open, inclusive, and tolerant, where even difficult topics can be addressed.</p><p>&ldquo;It should feel safe to come to work, especially in a lab environment where we handle chemicals and technical equipment. It is important that we follow the laws and regulations in place to protect both health and safety,&rdquo; says Carin Wibom, research engineer at the Department of Clinical Microbiology at Ume&aring; University. She also highlights ergonomics as a key factor, noting that repetitive tasks and poor working postures can place significant strain on the body.</p><p>Since the pandemic, systematic work environment efforts have fallen behind &ndash; a natural consequence of a period dominated by crisis management. Now, Carin Wibom wants to see change.</p><p>&ldquo;My motivation is to establish routines for how we systematically work with both lab safety and office ergonomics. But just as important is the psychosocial work environment &ndash; how we treat each other and build a culture where everyone feels included and seen,&rdquo; she says.</p><h2 id="info2" data-magellan-target="info2">More structure and routines</h2><p>Despite good intentions and growing attention to work environment issues, major challenges remain &ndash; especially when it comes to turning ambitions into concrete and sustainable routines in everyday work.</p><p>Mikaela Lagerqvist hopes for more systematic approaches to work environment efforts, with clearer structures and increased support from the department&rsquo;s leadership.</p><p>&ldquo;Of course, we would like to see work environment issues prioritized higher on the agenda. We are working toward closer collaboration with leadership, and we feel that we have a good dialogue that will hopefully move things forward,&rdquo; she says.</p><h2 id="info3" data-magellan-target="info3">A time consuming role</h2><p>Currently, there is no set time allocation for how much work a work environment representative is allowed to dedicate to the role.</p><p>&ldquo;In theory, we are entitled to the time needed, but in practice it is often difficult to balance work environment responsibilities with our regular duties, such as lab work or teaching,&rdquo; says Carin Wibom.</p><p>The department is growing rapidly, and once the staff size reaches a certain level, the role of work environment representative could potentially become a dedicated position &ndash; without drawing from research funding. This would allow sufficient time to be allocated for the important work carried out by the representatives.</p><p><em>How can people reach you for help?</em></p><p>&ldquo;You are always welcome to stop by the office, send an email, or contact us via Teams. We will get back to you as soon as we can!&rdquo; says Mikaela Lagerqvist.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9842-251020-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9842-251020-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9842-251020-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9842-251020-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9842-251020-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/cc0dc5daf140403fbd293b466f33ec11/arbetsmijoombud-ucmr-9842-251020-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Carin Wibom, Mikaela Lagerqvist and Ylva Hedberg Fransson welcome employees to get in touch.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div>/en/news/the-representatives-fighting-for-a-better-work-environment_12147721//en/news/2025-mims-clinical-research-fellowship-awarded_12147750/The Laboratory for Molecular Infection Medicine Sweden (MIMS) has announced the winner of its national Clinical Research Fellowship (CRF) program for 2025.Wed, 29 Oct 2025 08:29:49 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/b26223fc3c8d4f42948fd3e8feb556da/lind-alicia-0436-241203-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/b26223fc3c8d4f42948fd3e8feb556da/lind-alicia-0436-241203-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/b26223fc3c8d4f42948fd3e8feb556da/lind-alicia-0436-241203-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/b26223fc3c8d4f42948fd3e8feb556da/lind-alicia-0436-241203-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/b26223fc3c8d4f42948fd3e8feb556da/lind-alicia-0436-241203-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/b26223fc3c8d4f42948fd3e8feb556da/lind-alicia-0436-241203-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Alicia Lind at University Hospital of Ume&aring; and Ume&aring; University is the winner of the national Clinical Research Fellowship (CRF) program for 2025.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>An international panel of clinical and basic researchers has awarded the fellowship to <strong>Alicia Lind</strong> at Norrland University Hospital, Ume&aring; to conduct research on improving diagnostics and outcomes of post-covid condition.</p><p>Alicia is a specialist physician in anesthesiology and intensive care at Norrland University Hospital, and a researcher at the Department of Diagnostics and Intervention at Ume&aring; University. Her research focuses on the interaction between metabolism and the immune system in severe infections such as sepsis and COVID-19. She holds a medical degree and a PhD in clinical microbiology from Ume&aring; University. She has been actively working in the field of precision diagnostics at Ume&aring; University.</p><p>In her MIMS CRF project, she aims to investigate the nature, dynamics, and mechanisms of long-term health effects following COVID-19. More specifically, she wants to identify sub-phenotypes of post-COVID condition (PCC) to guide personalized rehabilitation and treatment and develop predictive algorithms using high-resolution immunometabolic profiling to enhance diagnostics, pathophysiological understanding, and prognostication of PCC.</p><p>Alicia says, <em>"Why some individuals develop long-term complications after COVID-19, while others recover quickly, remains a pressing question. So far, the lack of high-quality clinical cohorts and biobanks has hampered progress in this critical area of research. Our clinical cohort study, CoVUm, may change that. With its large size, wide spectrum of disease severity, and exceptionally low drop-out rate, it is one of the few studies worldwide capable of providing long-term insights into post-COVID1 of 4condition (PCC). This creates a rare opportunity for us to connect metabolic and immunological changes with long-term clinical outcomes. Through broad, interdisciplinary collaborations, we are conducting in-depth studies of immunometabolic signatures alongside conventional biomarkers of immune response and organ dysfunction. Our group includes expertise in clinical medicine, analytical chemistry, and data-driven science &ndash; with the potential to develop new methods and knowledge relevant not only to COVID-19 but also to other post-infectious conditions. I chose Prof Martin Rosvall as a collaborator, since he and his group specialize in multivariate data analysis with machine learning methods in biological systems, expertise that is required in this project with complex and large datasets on multiple levels."</em></p><p>In her MIMS CRF project, Alicia is collaborating with Martin Rosvall, a professor at Icelab in the Department of Physics at Ume&aring; University, where she will have access to machine learning methods designed to identify patterns in complex biological data.</p><p>Martin says <em>"Alicia's work on post-COVID condition tackles a challenge that illustrates why interdisciplinary collaboration matters. The CoVUm cohort generates massive, multilayered datasets that no single approach can fully illuminate. My group brings machine learning methods designed to find patterns in complex biological data, but these methods only reveal meaningful insights when guided by deep clinical and biochemical understanding. The MIMS Clinical Research Fellowship provides exactly the protected research time and resources Alicia needs to develop the project. With these resources, we can move beyond simply describing post-COVID symptoms to identifying the immunometabolic signatures that distinguish different patient subgroups&mdash;signatures that could reveal why some people develop long-term complications while others recover completely."</em></p><p>MIMS Clinical Research Fellowships provide guaranteed research time and fund the fellow&rsquo;s research up to a total value of 3.2 mio SEK.</p><p>Oliver Billker, Director of MIMS, says: <em>"We are delighted to welcome Alicia to the MIMS community. Her project is a great example of the type of interdisciplinary and collaborative work we want to foster. It provides an opportunity for international collaboration in molecular medicine, which is at the core of our partnership with the European Molecular Biology Laboratory (EMBL) and its Nordic Partnership."</em></p><p>MIMS receives funding from the Swedish Research Council, the Knut and Alice Wallenberg Foundation, the Kempe Foundations and Ume&aring; University to foster the next generation of outstanding researchers in infection medicine. It is the Swedish node in the EMBL network, to which it is connected through the Nordic EMBL Partnership for Molecular Medicine.</p>/en/news/2025-mims-clinical-research-fellowship-awarded_12147750//en/news/eu-invests-in-umea-research--16-projects-tackle-major-societal-challenges_12146879/How do environmental toxins affect the brain? Can AI support teachers in the classroom? And how might autonomous machines contribute to a greener industry? Researchers at Umeå University have been awarded over €10 million in EU funding to address some of the most pressing issues of our time.Fri, 24 Oct 2025 09:25:54 +0200<p>Ume&aring; University is participating in 16 new research projects that have collectively received more than &euro;10.2 million &ndash; approximately SEK 112 million &ndash; through the EU&rsquo;s 2024 funding calls.</p><p>&ldquo;This funding strengthens the university&rsquo;s international research collaborations and highlights how knowledge developed here helps push the boundaries of science,&rdquo; says Agneta H&aring;nell Plamboeck, head of the Research Support Office at Ume&aring; University.</p><p>Support from programmes such as Horizon Europe and Erasmus+ enables researchers at the university to collaborate with colleagues, companies, and organisations across Europe. Together, they are developing new knowledge &ndash; ranging from the tiniest building blocks of life to large-scale innovations that advance health, sustainability, and technology.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/dcf1ee7fe611465fbac5264a581bf01e/marta-bally-5538-250325-mpn6.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/dcf1ee7fe611465fbac5264a581bf01e/marta-bally-5538-250325-mpn6.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/dcf1ee7fe611465fbac5264a581bf01e/marta-bally-5538-250325-mpn6.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/dcf1ee7fe611465fbac5264a581bf01e/marta-bally-5538-250325-mpn6.jpg?mode=crop&amp;width=640 640w, /contentassets/dcf1ee7fe611465fbac5264a581bf01e/marta-bally-5538-250325-mpn6.jpg?mode=crop&amp;width=854 854w, /contentassets/dcf1ee7fe611465fbac5264a581bf01e/marta-bally-5538-250325-mpn6.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>One of the researchers awarded EU funding is Marta Bally at the Department of Clinical Microbiology (to the right, here with postdoc Malgorzata Graul). She investigates the invisible and largely unknown protective layer of our cells, which, when disrupted, may contribute to cancer, autoimmune diseases, and neurodegenerative conditions.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><h2 id="info0" data-magellan-target="info0">Curious about what the researchers are working on?</h2><p>Click the expandable headings below to explore the projects and discover how Ume&aring; researchers contribute to scientific progress and societal development.<br><br></p><h2 id="info1" data-magellan-target="info1">HORIZON EUROPE</h2><h2 id="info2" data-magellan-target="info2">Pillar I: Scientific excellence<br><br></h2><h3>European Research Council &ndash; Starting Grant</h3><p class="foldable">ARIMETH &ndash; tracing methane emissions from Arctic rivers</p><p><strong>Methane is one of the most powerful greenhouse gases &ndash; many times stronger than carbon dioxide. Arctic rivers may be a hidden source, but researchers still know little about how these emissions arise and vary. The ARIMETH project aims to fill that gap.</strong></p><p>The team combines field experiments, high-resolution measurements with advanced sensors, isotope analyses, and modelling to understand the processes driving methane&rsquo;s journey from land to river and into the atmosphere. By linking local studies with pan-Arctic comparisons, the project will develop new models to better predict both present and future emissions.</p><p>The results could offer groundbreaking insights into the Arctic carbon cycle &ndash; and reveal whether current climate models have underestimated the role of rivers in global warming.</p><p><strong>Researcher:</strong>&nbsp;<a href="~/link/f7439a65265c41869a7b464e080e2d3b.aspx">Gerard Rocher-Ros</a>, Department of Ecology, Environment and Geoscience<br><strong>Funding awarded:</strong> &euro;1,902,360</p><p class="foldable">MicroIMMUNE &ndash; mapping tiny proteins with a big impact</p><p><strong>Our immune system protects us every day &ndash; but many of the smallest proteins that regulate its functions remain a mystery. MicroIMMUNE aims to change that.</strong></p><p>Within our DNA are genes that give rise to very small proteins &ndash; known as microproteins &ndash; which have so far escaped scientific attention. Researchers in MicroIMMUNE are developing new methods to identify these proteins, map where they are found in immune cells, and uncover how they influence immune responses under different conditions.</p><p>By systematically building an atlas of microproteins and their interactions, the project seeks to reveal what has long been hidden. These discoveries could provide entirely new insights into how the immune system works &ndash; and pave the way for future treatments, such as antibiotics that mimic microproteins to strengthen the body&rsquo;s defences against infection.<br><br><strong>Researcher:&nbsp;</strong><a href="~/link/71e2c62213f84c0ba36f9991a428fefc.aspx">Iker Valle Aramburu</a>, Department of Molecular Biology<br><strong>Funding awarded:</strong> &euro;1,500,000</p><h3>European Research Council &ndash; Synergy Grant</h3><p class="foldable">RESYDE &ndash; re-engineering life&rsquo;s building blocks</p><p><strong>How does a flower know what shape to take? And why do living organisms develop the forms and patterns we see in nature? RESYDE explores the biological processes that break symmetry in cells and tissues &ndash; one of life&rsquo;s great mysteries.</strong></p><p>The research team uses the plant&nbsp;<em>Arabidopsis</em> as a model. By combining gene analyses, advanced microscopy, experiments that alter protein function, and computational modelling, they study how molecules, signals and mechanical forces guide cell development. Using a virtual &ldquo;4D cell template&rdquo;, they can simulate these processes and test hypotheses about how forms arise and change.</p><p>The goal is to achieve a predictive understanding of how organisms develop their shapes. In the long run, this knowledge could be highly valuable for both medicine and agriculture &ndash; for example by guiding how tissues are built or how plants grow.</p><p><strong>Researcher:</strong>&nbsp;<a href="~/link/7fa34837022c4fdeb6932a274829a3b0.aspx">Stephan Wenkel</a>, Department of Plant Physiology<br><strong>Funding awarded:</strong> &euro;2,413,756&nbsp;</p><h3>Marie Skłodowska-Curie Actions &ndash; Doctoral Networks</h3><p class="foldable">ENGAGE &ndash; paving the way for future green and AI-controlled work machines</p><p><strong>Excavators, forestry machines and port cranes are essential to society &ndash; but they need to become safer, smarter and more environmentally friendly. ENGAGE trains the next generation of researchers to develop AI-powered mobile work machines for the demands of tomorrow.</strong></p><p>The project brings together European industrial leaders such as Volvo, Bosch and Liebherr with researchers in AI, robotics and physics from universities in Sweden, Finland, Germany and Austria, as well as tech companies like Algoryx. Within this collaborative framework, thirteen doctoral students are being trained in simulation and AI to develop machines that can operate more autonomously, with a lower carbon footprint and improved safety.</p><p>The initiative combines scientific and engineering expertise with practical knowledge of mobile work machines used in construction, agriculture and forestry. In this way, ENGAGE aims to strengthen European industry and make every day working machines a key part of the green transition.</p><p><strong>Researcher:</strong>&nbsp;<a href="~/link/e4bf4710029341f895bd7364fe9c0802.aspx">Martin Servin</a>, Department of Physics<br><strong>Funding awarded:</strong> &euro;108,210</p><p class="foldable">GLYCOCALYX &ndash; uncovering the invisible shield of our cells</p><p><strong>Every cell in your body wears a protective "sugar coat" &ndash; the glycocalyx. It shields the cell and helps it communicate, yet despite its crucial role in immunity, brain function, and tissue repair, much about it remains unknown.</strong></p><p>The European doctoral network GLYCOCALYX brings together 15 early-career researchers to find out how this delicate layer is built, how it functions, and what happens when it fails. When the system is disrupted, it can contribute to diseases such as cancer, autoimmune disorders, and neurodegeneration. Excessive degradation can also lead to severe infections, sometimes with fatal consequences.</p><p>By combining chemistry, physics, and biology, the researchers are mapping the glycocalyx and developing new tools to make the invisible visible. Their work could pave the way for innovative diagnostic methods and treatments &ndash; and provide a deeper understanding of our cells and their invisible shield.</p><p><strong>Researchers:</strong>&nbsp;<a href="~/link/1c0a359d7b484a57887181ad3ee98fab.aspx">Marta Bally</a>&nbsp;and&nbsp;<a href="~/link/b57dd5a6ea894941a99e05b60515339a.aspx">Anne-Marie Fors Connolly</a>, Department of Clinical Microbiology<br><strong>Funding awarded:</strong> &euro;649,260&nbsp;</p><p class="foldable">MIPrecise &ndash; making cancer diagnostics faster and fairer</p><p><strong>Where you live should not determine how quickly you get a cancer diagnosis. MIPrecise aims to develop simple, robust, and eco-friendly tests that can detect cancer earlier &ndash; even in smaller clinics &ndash; making care more equitable.</strong></p><p>Instead of fragile biological reagents, the researchers use smart plastic molecules, called imprinted polymers. These act as artificial antibodies and can be tailored to recognise biomarkers &ndash; molecules in the body that signal cancer. The technology is used to develop tests that are both robust and accurate, and can be applied to liquid biopsies, home testing, and guide to more precise, personalised cancer therapies.</p><p>Within the European doctoral network MIPrecise, early-career researchers receive interdisciplinary training combining materials science, cell analyses, and clinical testing. The goal is to create new diagnostic platforms and contribute to more sustainable cancer diagnostics &ndash; benefiting patients, healthcare, and the environment.</p><p><strong>Researcher:</strong>&nbsp;<a href="~/link/ff3d0a52d56a45d8b10cb1301ab338cf.aspx">Jenny Persson</a>, Department of Molecular Biology<br><strong>Funding awarded:&nbsp;</strong>&euro;324,630</p><h3>Marie Skłodowska-Curie Actions &ndash; Postdoctoral Fellowships</h3><p class="foldable">CORALS &ndash; building ultra-fast data technology with light</p><p><strong>Today&rsquo;s digital technology is both energy-hungry and approaching its speed limits. CORALS explores whether light can replace electricity &ndash; potentially paving the way for faster, more energy-efficient computers.</strong></p><p>The project focuses on so-called polaritons, hybrid particles where light and matter interact. These particles can oscillate between light and matter states at extremely high speeds, a phenomenon known as Rabi oscillation. So far, such oscillations have been too short-lived for practical use, but CORALS aims to investigate whether more stable signals can be achieved.</p><p>If successful, the research could lead to optical switches that make computers both much faster and possibly more energy-efficient than today&rsquo;s devices &ndash; and eventually open doors to entirely new forms of quantum and light-based information technology.</p><p><strong>Researchers:</strong>&nbsp;<a href="~/link/873f450f972b440383861538726a54e6.aspx">Ben Johns</a>&nbsp;and&nbsp;<a href="~/link/5ea5c52cb8224f18944630d14e7e799a.aspx">Nicol&ograve; Maccaferri</a>, Department of Physics<br><strong>Funding awarded:</strong> &euro;252,180</p><p class="foldable">Cryo-GraPoTSS &ndash; revealing how bacteria spread antibiotic resistance</p><p><strong>Antibiotic-resistant bacteria pose an increasing threat to public health. One key reason is that bacteria can transfer resistance genes between each other using tiny protein machines &ndash; known as conjugative type 4 secretion systems (T4SS).</strong></p><p>These systems function like microscopic tunnels, passing genes from one bacterium to another. In the Cryo-GraPoTSS project, researchers will for the first time map what these systems look like in Gram-positive bacteria &ndash; a group that frequently causes serious hospital-acquired infections. Using cryo-electron microscopy and tomography, they aim to produce high-resolution images of T4SS in Enterococcus faecalis, directly in its natural environment.</p><p>By uncovering how these molecular machines are built and how they work, the researchers hope to identify new targets for antibiotics &ndash; a crucial piece of the puzzle in the fight against antibiotic resistance.</p><p><strong>Researchers:&nbsp;</strong><a href="~/link/74c44e57660641bba0b41ffe53be4bd4.aspx">Kieran Deane-Alder</a>&nbsp;and&nbsp;<a href="~/link/a88ab036b4fa4de7877561480f0ae3ba.aspx">Ronnie Berntsson</a>, Department of Medical Biochemistry and Biophysics<br><strong>Funding awarded:</strong> &euro;236,340</p><h3>Research infrastructures<br><br></h3><p class="foldable">SoGreen &ndash; illuminating the social dimension of the green transition</p><p><strong>The green transition is not only about technology &ndash; it also affects how we live, work and build our communities.&nbsp;SoGreen develops methods to study how the social aspects of the transition can help make it fairer and more inclusive.</strong></p><p>By gathering knowledge about people&rsquo;s living conditions and attitudes, researchers can offer important insights into how the transition impacts different groups in society, depending on factors such as age, income, and other social circumstances. SoGreen is developing a new questionnaire and geospatial data, laying the groundwork for better analysis and decision-making.</p><p>The project aims to give policymakers tools to better understand the social challenges &ndash; and to support inclusive policies for a green transition that takes people&rsquo;s diverse experiences into account.</p><p><strong>Researcher:</strong> <a href="~/link/a748b03f92c348c282f54b65937c4027.aspx">Gunnar Malmberg</a>, Department of Geography<br><strong>Funding awarded:</strong>&nbsp;&euro;29,625</p><h2 id="info3" data-magellan-target="info3">Pillar II: Global challenges and European industrial competitiveness</h2><h3><br>Cluster 1: Health</h3><p class="foldable">EXPOSIGNALZ &ndash; investigating the link between pollutants and Alzheimer&rsquo;s</p><p><strong>Could air pollution and other environmental chemicals contribute to dementia, including Alzheimer&rsquo;s disease? EXPOSIGNALZ investigates how everyday chemical exposures affect the brain.</strong></p><p>Using laboratory experiments, advanced brain models, and studies in different population groups, the researchers aim to identify which substances are harmful, how they impact the brain over time, and whether they may contribute to disease development.</p><p>The project seeks to develop new biomarkers for early diagnosis and provide policymakers with knowledge and tools to reduce exposure and prevent disease.</p><p><strong>Researcher:</strong>&nbsp;<a href="~/link/32112574837542c9acbb60aedeca3c95.aspx">Anna Oudin</a>, Department of Epidemiology and Global Health<br><strong>Funding awarded:</strong> &euro;475,090</p><h3>Cluster 4: Digital, industry and space</h3><p class="foldable">XSCAVE &ndash; developing smart machines for construction and forestry</p><p><strong>Self-driving machines that can understand and adapt to their surroundings &ndash; that is the vision of XSCAVE. The project develops AI-solutions designed to make heavy-duty vehicles smarter, more environmentally friendly, and better able to support industries facing labour shortages.</strong></p><p>The researchers combine deep learning with physics-based models and data from machines in operation to create autonomous control systems that are fast and reliable. These systems will be able to adjust movements and navigation to suit both task and terrain &ndash; driving, excavating, and loading in loose soil, rocky ground, uneven forest terrain and snow.</p><p>In collaboration with industrial partners such as Algoryx, Komatsu, Novatron, and Toshiba, the technology will be tested in real-world environments. The goal is to create machines that can operate efficiently, safely, and with lower fuel consumption &ndash; even without a driver.</p><p><strong>Researcher:</strong> <a href="~/link/e4bf4710029341f895bd7364fe9c0802.aspx">Martin Servin</a>, Department of Physics<br><strong>Funding awarded:</strong>&nbsp;&euro;714,625&nbsp;</p><h3>Cluster 6: Food, bioeconomy, natural resources, agriculture and environment</h3><p class="foldable">ArcticKnows &ndash; shaping the future of the Arctic with local knowledge</p><p><strong>How can Arctic communities and Indigenous peoples take an active role in shaping the development of their regions? ArcticKnows brings together researchers, businesses, and local stakeholders to amplify local voices in the transition towards more sustainable and equitable economies.</strong></p><p>The project bridges research, traditional knowledge, and practical work. In close collaboration with local communities, pilot initiatives are being developed in nature-based tourism, small-scale agriculture, and fisheries across Sweden, Norway, Finland, and Greenland. Emphasis is placed on including women and youth, as well as ensuring Indigenous perspectives are represented in decision-making.</p><p>The aim is to pave the way for new approaches where people in the Arctic can shape their own future, and where their knowledge becomes a valuable resource for the global transition.</p><p><strong>Researcher:</strong> <a href="~/link/6f100d6a98684f2da25d15c6c807c513.aspx">Linda Lundmark</a>, Department of Geography<br><strong>Funding awarded:</strong>&nbsp;&euro;363,075</p><p class="foldable">CoCo &ndash; aiding coexistence between agriculture and wildlife</p><p><strong>How can farmers and wild animals live alongside each other without constant conflict? CoCo addresses the growing challenges that come with the recovery of large carnivores and other wildlife in Europe.</strong></p><p>The project brings together thousands of farmers, hunters, and landowners across 12 countries. Researchers use collaborative methods &ndash; including policy analysis, interviews, field visits, focus groups, and modelling &ndash;&nbsp;to explore how people and wildlife can share the landscape, and how different stakeholders&rsquo; experiences and values influence decision-making.</p><p>The goal is to develop a &ldquo;Roadmap for Coexistence&rdquo; with practical recommendations that reduce conflicts, promote cooperation among stakeholders, and support sustainable, multi-functional landscapes &ndash; for both humans and wildlife.</p><p><strong>Researcher:</strong>&nbsp;<a href="~/link/b912ff988f754c4eb82ebec2eb23e87d.aspx">Camilla Sandstr&ouml;m</a>, Department of Political Science<br><strong>Funding awarded:</strong> &euro;246,380</p><p class="foldable">FlavourFerm &ndash; making plant-based food tastier and more nutritious</p><p><strong>Why don&rsquo;t more people choose plant-based food? Taste and texture are often the stumbling blocks. The FlavourFerm project aims to change that &ndash; by developing fermentation techniques that make green alternatives both tastier and more nutritious.</strong></p><p>The researchers combine traditional methods with modern precision fermentation, programming yeast to produce specific proteins &ndash; such as milk proteins without any animal origin. They also use legumes to cultivate fungal mycelium with meat-like properties.</p><p>These new ingredients will be tested in plant-based cheese, meat and milk &ndash; and scaled up to pilot and pre-commercial levels in collaboration with food companies across Europe. The goal is to create plant-based food that matches animal-based products in flavour and nutritional value &ndash; but is more sustainable for both people and the planet.</p><p><strong>Researchers:</strong> <a href="~/link/0034b495c740417e93862321442afc71.aspx">Armando Perez-Cueto</a>, Department of Food, Nutrition and Culinary Science, and <a href="~/link/4fc80be3f056492eb675ee2202eedb33.aspx">Danielle Wilde</a>, Ume&aring; Institute of Design<br><strong>Funding awarded:</strong>&nbsp;&euro;393,392</p><h2 id="info4" data-magellan-target="info4">OTHER PROGRAMMES</h2><h2 id="info5" data-magellan-target="info5">Erasmus+</h2><p class="foldable">AI2PI &ndash; preparing teachers for AI in the classroom</p><p><strong>How can schools and teacher education together respond to societal change brought about by AI tools such as ChatGPT? The AI2PI Teacher Academy develops courses, networks, and practical models to help teachers understand and use AI responsibly.</strong></p><p>Digitalisation is reshaping both how education unfolds, and the skills students will need in the future. Beyond technical know-how, competencies such as critical thinking, collaboration, and empathy are becoming increasingly important &ndash;&nbsp;especially as AI technologies enter the classroom.</p><p>To support teachers in navigating this shift, seven universities, schools, and teacher-training organisations across Europe are joining forces. Together, they are developing short course modules (micro-credentials), a shared framework for AI literacy in schools, and communities of practice where educators can exchange experiences.</p><p>The goal is safe, research-informed teaching and learning with a focus on AI &ndash;&nbsp;helping young people act responsibly as citizens in a digital society.</p><p><strong>Researcher:</strong> <a href="~/link/7ff58d2ae47a41de84e38f7cff128387.aspx">Maria R&ouml;nnlund</a>, Department of Applied Educational Science<br><strong>Funding awarded:</strong>&nbsp;&euro;152,319</p><h2 id="info6" data-magellan-target="info6">Reseach Fund for Coal and Steel (RCFS)</h2><p class="foldable">AUSNANITE &ndash; baking stronger and more climate-smart steel</p><p><strong>Steel is one of our most important construction materials, but producing it requires a lot of energy and generates large amounts of carbon dioxide (CO₂). Now, researchers are testing a new way to make stronger, more climate-friendly steel &ndash; by <em>baking</em>&nbsp;it.</strong></p><p>In the AUSNANITE project, the team explores whether the well-established hardening method known as <em>austempering</em> can be combined with a controlled &ldquo;baking&rdquo; process to form a new type of ausferritic structure. This structure offers a unique combination of high strength and toughness &ndash; properties that make the steel particularly resistant to impact and wear, for example in construction and mining equipment.</p><p>The approach also promises a far more energy-efficient production of bar steel and forgings. Unlike conventional methods, it eliminates the need to reheat the steel a second time, substantially reducing both costs and CO₂ emissions.</p><p>If successful on an industrial scale, even a partial adoption of the process may reduce emissions by hundreds of thousands of tonnes each year. The result could be steel that lasts longer, costs less to produce, and supports Europe&rsquo;s transition towards a more sustainable and competitive industry.</p><p><strong>Researcher:</strong> <a href="~/link/8dc84e451ed7496e8cfd907388115792.aspx">Richard Larker</a>, Department of Applied Physics and Electronics<br><strong>Funding awarded:</strong>&nbsp;&euro;254,171</p>/en/news/eu-invests-in-umea-research--16-projects-tackle-major-societal-challenges_12146879//en/news/high-levels-of-hif2-may-impair-high-risk-paediatric-neuroblastoma_12147086/High levels of a specific protein can reduce the growth of tumour cells in neuroblastoma, a form of cancer that affects the sympathetic nervous system in young children. This is shown in a new study by researchers at Umeå University and Karolinska Institutet, Sweden. The protein in question also seems to cause the cancer cells to change into less aggressive cells.Thu, 23 Oct 2025 11:10:44 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/644b116b36404a479d202e4ad67127ad/johan_holmbergs_forskargrupp.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/644b116b36404a479d202e4ad67127ad/johan_holmbergs_forskargrupp.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/644b116b36404a479d202e4ad67127ad/johan_holmbergs_forskargrupp.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/644b116b36404a479d202e4ad67127ad/johan_holmbergs_forskargrupp.jpg?mode=crop&amp;width=640 640w, /contentassets/644b116b36404a479d202e4ad67127ad/johan_holmbergs_forskargrupp.jpg?mode=crop&amp;width=854 854w, /contentassets/644b116b36404a479d202e4ad67127ad/johan_holmbergs_forskargrupp.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>The Ume&aring; University researchers behind the study: Eirini Antoniou, Subhamita Maitra, Johan Holmberg and Caroline Lindehell</p><span class="bildPhotografer"><span class="photo">Image</span>Olof Jansson </span></div></div><p>"The findings increase our understanding of how neuroblastoma develops and can hopefully contribute to new treatments in the long term," says Johan Holmberg, professor of molecular tumour biology at Ume&aring; University and one of the researchers behind the study.</p><p>Neuroblastoma is a form of cancer that affects the sympathetic nervous system in young children and is often difficult to treat, especially when the tumour cells have many copies of a gene called <em>MYCN</em>. In the new study, the researchers have focused on a protein called <em>HIF2&alpha;</em>.</p><p>When the researchers induced high levels of HIF2&alpha; in neuroblastoma cells with many copies of the MYCN gene, they could see a sharp decrease in the protein expressed by the MYCN gene. At the same time, the expression of genes typical of cells that produce noradrenaline in the adrenal medulla increased. This suggests that the tumour cells began to resemble more mature cells in the sympathetic nervous system. The cells also stopped dividing as quickly and they developed long protrusions; a sign that they are maturing.</p><p>In experiments in a mouse model of neuroblastoma, the growth of the tumours was significantly reduced when high levels of HIF2&alpha; were induced. When analysing patient samples from children with neuroblastoma, the researchers found that high levels of the gene, <em>EPAS1</em>, which codes for the protein HIF2&alpha; were associated with low levels of MYCN and with genes that are typical of more mature cells. In addition, patients with high levels of EPAS1 generally had a better prognosis.</p><p>The study thus challenges a previous view that HIF2&alpha; would act as a driver of cancer in neuroblastoma. Instead, the results suggest that the protein may in some cases have a slowing function and promote maturation into less aggressive cells.</p><p>"The discovery may prove significant, but there is a long way to go before new treatments based on this can be considered," says Johan Holmberg.</p><p>Neuroblastoma accounts for about six percent of cancer cases among children. There are several different degrees of severity of the disease that affect the prognosis. Treatments have improved in recent decades so that three out of four children affected survive the disease. However, survival is unfortunately worse for patients with many copies of the MYCN gene.</p><p>The study, which is supported by the Swedish Childhood Cancer Foundation, the Swedish Cancer Society, the Kempe Foundation and the Faculty of Medicine's Strategic Research Resource at Ume&aring; University, is published in the scientific journal PNAS.&nbsp;</p>/en/news/high-levels-of-hif2-may-impair-high-risk-paediatric-neuroblastoma_12147086//en/news/from-journal-stress-to-ai-solution_12147261/Medical student Edvin Tidevall worked as a medical assistant during the summer and was amazed at how much time was spent on documentation. He soon discovered that one of the biggest time thieves was record keeping. The solution was an AI service, which in turn became the company Leapscribe, which was quickly bought by the Nordic region's largest e-health providers. And on his business journey, Edvin Tidevall received valuable help from the innovation system at Umeå University.Thu, 23 Oct 2025 08:31:44 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/d67ad76cf49d433c9c2c2889a87fd8d3/leapscribe_20253.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d67ad76cf49d433c9c2c2889a87fd8d3/leapscribe_20253.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d67ad76cf49d433c9c2c2889a87fd8d3/leapscribe_20253.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d67ad76cf49d433c9c2c2889a87fd8d3/leapscribe_20253.jpg?mode=crop&amp;width=640 640w, /contentassets/d67ad76cf49d433c9c2c2889a87fd8d3/leapscribe_20253.jpg?mode=crop&amp;width=854 854w, /contentassets/d67ad76cf49d433c9c2c2889a87fd8d3/leapscribe_20253.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>All co-founders of Leapscribe gathered together: Arvid &Ouml;stlund, Samir Jamehdar, Edvin Tidevall and Adrian Bagger Tor&auml;ng. Photo: Fanny Berglund (Studioformbar).</p></div></div><p>"When Leapscribe was still in its very early stages, I pitched the idea to the incubator Uminova Innovation, but because I had a connection to the university, I was put in touch with the Innovation Office at Ume&aring; University instead, and business developer Christopher Frisk," says Edvin Tidevall, who now works at Cambio, the company that bought his business.</p><h3>The business coach became an important sounding board</h3><p>"When we entered the Innovation Office, there was no finished product &ndash; Leapscribe was still in its infancy. The support was largely about general issues relating to business and entrepreneurship, but also about regulatory issues, which was crucial for us before we could start working with customers. Our business coach became an important sounding board and helped us deal with the many challenges that arise when you are new to entrepreneurship. That support was very valuable."</p><p>The idea, which Edvin Tidevall received help to turn into a company, is an AI assistant that automatically generates medical records during patient consultations. This frees up a lot of time and simplifies things for healthcare staff without compromising patient safety and integrity. The idea and the company were so successful that it was sold to Cambio last summer, where Edvin Tidevall is now working on developing and implementing the system.</p><h3>What message would you like to convey to other students or colleagues at Ume&aring; University who have an idea?</h3><p>"Dare to try. Starting a business is a challenge, but it is also a fantastic education in itself. You learn an incredible amount along the way. There is good support available through the Innovation Office &ndash; both for validating your idea and for finding the right team. So don't hesitate, take your idea to the Innovation Office and give it a try!"</p>/en/news/from-journal-stress-to-ai-solution_12147261//en/news/network-to-strengthen-collaboration-in-cancer-research_12146945/A new network brings together researchers at the university and in the region to strengthen collaboration and lay the foundation for continued development in the field of cancer.Wed, 22 Oct 2025 08:07:24 +0200<p>Cancer research in Ume&aring; is strong in terms of both depth and breadth. Researchers here have different backgrounds, expertise and perspectives, which creates good conditions for interdisciplinary collaboration. However, despite the geographical proximity between preclinical and clinical research environments at the university and within the region, there has often been a lack of natural meeting places for researchers.</p><p>"There has been a desire to build relationships, share experiences and find new ways forward together, which is why a research network in the field of cancer has been created," says Lotta Edvinsson, project manager for the Ume&aring; Comprehensive Cancer Centre.</p><p>The first meeting was held last week and served as a kick-off for researchers in fields ranging from nursing to molecular biology. Research leaders, future research leaders and representatives of support functions gathered to listen to inspirational lectures and short presentations on infrastructure, followed by a mingle.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/1197e4b9004e4f72ad007e760f8787be/img_14143.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14143.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14143.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/1197e4b9004e4f72ad007e760f8787be/img_14143.jpg?mode=crop&amp;width=640 640w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14143.jpg?mode=crop&amp;width=854 854w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14143.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Tufve Nyholm, Head of Department of Diagnostics and Intervention</p><span class="bildPhotografer"><span class="photo">Image</span>Anja Hansen Knutsson</span></div></div><p>"Collaboration, cooperation and interdisciplinary thinking provide opportunities to further strengthen existing projects and create new approaches and opportunities for research in the field of cancer. A prerequisite for finding synergies is that researchers get to know each other, talk and explore opportunities," says Tufve Nyholm, Head of the Department of Diagnostics and Intervention.</p><h3>Common needs and requirements</h3><p>In addition to the researchers' own wishes, there are formal requirements. To become a Comprehensive Cancer Centre (CCC), increased collaboration between preclinical and clinical research is required.</p><p>"We have a lot to gain from bringing our resources and expertise together. It is a matter of both meeting our own needs for closer collaboration and fulfilling external requirements," says Tufve Nyholm.</p><h3>Good examples can inspire others</h3><p>Daniel &Ouml;hlund and Erik Chorell are good examples of successful cross-border collaboration.</p><p>"Research in life sciences is so complex today that no one can have all the expertise needed in a single laboratory. To ensure impact and quality in projects, extra help is often required. Infrastructures offer this support and are therefore important to use," says Erik Chorell, Associate Professor at the Department of Chemistry and responsible for the Umu node of the national infrastructure Chemical Biology Consortium Sweden (CBCS).</p><p>Daniel &Ouml;hlund, associate professor at the Department of Diagnostics and Intervention and oncologist at the Cancer Centre, approached CBCS with a specific question, but believes that a broader network of contacts can help to forge new collaborations as early as the planning stage.</p><p>"Breakthroughs in cancer research require collaboration between different disciplines. More collaborations can be facilitated through networks such as this one, and Ume&aring; CCC has an important role to play in this regard," Daniel says.</p><p>The goal is to establish a viable research network in the field of cancer in Ume&aring;. Work is now continuing to develop the format and create more opportunities for exchange and collaboration.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/1197e4b9004e4f72ad007e760f8787be/img_14023.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14023.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14023.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/1197e4b9004e4f72ad007e760f8787be/img_14023.jpg?mode=crop&amp;width=640 640w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14023.jpg?mode=crop&amp;width=854 854w, /contentassets/1197e4b9004e4f72ad007e760f8787be/img_14023.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Erik Chorell and Daniel &Ouml;hlund.</p><span class="bildPhotografer"><span class="photo">Image</span>Anja Hansen Knutsson</span></div></div><p>&nbsp;</p>/en/news/network-to-strengthen-collaboration-in-cancer-research_12146945//en/news/rethinking-arctic-security-in-a-time-of-tension-and-thaw_12145019/On 18 September, researchers, policymakers, and experts gathered in Oslo for the Arctic Security Conference 2025 to address one central question: how to manage polarisation and fragmentation in the Arctic. The programme spanned climate change, geopolitical tensions, indigenous knowledge, and hybrid threats, underlining the urgent need for cooperation and research to inform decisions at every level of society.Wed, 15 Oct 2025 15:44:36 +0200<h2 id="info0" data-magellan-target="info0">Young researchers set the tone</h2><p>The day before the main conference, early-career researchers organised and led a series of workshops that set the stage for the discussions to follow. Although these sessions were officially separate, they felt very much like a first day of the conference &ndash; full of energy, exchange, and engagement &ndash; attracting a large and attentive audience. Their sessions covered a broad range of topics, demonstrating how the next generation of Arctic experts is already shaping the debate and paving the way for the more senior voices who took the floor the following day. One urgent issue was the rise of hybrid threats, with participants emphasising that only strong democratic institutions, social cohesion, and trust can prevent such dangers from undermining societies.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="4ac5d820-031b-4e81-a9a1-3b520cd042eb" data-contentname="BILD Paul">{}</div><p>&ldquo;It was inspiring to see how early-career researchers were not only participating but actively driving the conversation forward. Their initiative gave the event an energy that carried into the entire conference,&rdquo; says Paul Schmidt, doctoral student at the Department of Political Science and part of the Arctic Graduate School at Ume&aring; University. His reflections highlight the value of international arenas like this for connecting researchers across borders and disciplines.</p><h2 id="info1" data-magellan-target="info1">Politics in focus</h2><p>The official conference day opened to a packed hall, underscoring the high stakes and widespread interest in Arctic security. Norway&rsquo;s Minister of Foreign Affairs Espen Barth Eide, Saami Council representative Gunn-Britt Retter, Norwegian MP Ine Eriksen S&oslash;reide, and Michael Sfraga, former U.S. Arctic Ambassador-at-Large, all brought perspectives on the state of affairs in the region. The panel painted a nuanced picture of both cooperation and conflict. Particularly notable was Sfraga&rsquo;s clear statement that the United States would never attempt to purchase or annex Greenland but would respect borders and the rule of law &ndash; a message that drew attention as much for its clarity as for its symbolism.</p><p class="quote-center">Security and the environment are interconnected, and both demand stronger research and cooperation.</p><h2 id="info2" data-magellan-target="info2">Democracy and defence</h2><p>Later in the day, Norway&rsquo;s Chief of Defence, General Erik Kristoffersen, offered a keynote that resonated strongly with the audience. He underlined that while nations must be vigilant, it is neither possible nor desirable to defend against every conceivable threat. Above all, he stressed that democracy must remain central: &ldquo;No one wants to live in a country where the chief of defence and the chief of police run everyday life. We want to live in a democracy.&rdquo; His remarks echoed the earlier call for resilience rooted in strong institutions and civic trust, reminding participants that security in the Arctic is ultimately about the kind of society people want to preserve.</p><h2 id="info3" data-magellan-target="info3">Climate challenges overlooked</h2><p>While much of the discussion centred on geopolitics and defence, several speakers warned about the decline in Arctic climate research. With fewer opportunities for cross-border cooperation, nearly half of the Arctic has become a &ldquo;scientific blind spot.&rdquo; This lack of data undermines the accuracy of models and makes it harder for communities and policymakers to prepare for long-term environmental change. When participants stepped outside into 20-degree September warmth in Oslo, the reality was impossible to ignore: climate change has not paused simply because international attention has shifted.</p><p>&ldquo;We must not lose sight of the climate dimension. Security and the environment are interconnected, and both demand stronger research and cooperation,&rdquo; Paul reflects. His words underline the role that universities such as Ume&aring; can play in bridging science and society, ensuring that Arctic research continues to inform decisions in a rapidly changing world.</p>/en/news/rethinking-arctic-security-in-a-time-of-tension-and-thaw_12145019//en/news/the-nordic-cryonet-symposium_12145845/Cryo electron microscopy (cryoEM) is an important technique for biomedical researchers to study the structure and function of macromolecular complexes in isolation and inside cells. CryoNET is a Nordic network that aims to promote collaboration and knowledge sharing across national borders. A main goal is to help establish state-of-the-art cryoEM as a pillar of Nordic life science research. Thu, 16 Oct 2025 17:44:01 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/63266b27920d42269ebc761e07636e3c/img_6445.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/63266b27920d42269ebc761e07636e3c/img_6445.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/63266b27920d42269ebc761e07636e3c/img_6445.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/63266b27920d42269ebc761e07636e3c/img_6445.jpg?mode=crop&amp;width=640 640w, /contentassets/63266b27920d42269ebc761e07636e3c/img_6445.jpg?mode=crop&amp;width=854 854w, /contentassets/63266b27920d42269ebc761e07636e3c/img_6445.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Group photo of the participants of the cryoNET Symposium 2025</p><span class="bildPhotografer"><span class="photo">Image</span>Ainhoa Querejeta</span></div></div><p>The symposium, which took place on the 1st to the 2nd of October at Ume&aring; University, brought together 140 at all career stages - from master&rsquo;s students to professors. Over these two days, invited speakers, selected talks by participants, poster and networking sessions highlighted the latest discoveries in the field.</p><p>What stood out most was the atmosphere: a shared enthusiasm for meeting in person and strengthening the community. As Rooshanie Ejaz, a student supported by the Novo Nordisk Foundation, noted:</p><p class="quote-center">Since lab work can often be quite independent, events like these are a great opportunity to build connections and feel part of a vibrant community</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/63266b27920d42269ebc761e07636e3c/processed-46b7c7dd-4bca-4d1c-955a-7a8d27fbf6d8.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/63266b27920d42269ebc761e07636e3c/processed-46b7c7dd-4bca-4d1c-955a-7a8d27fbf6d8.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/63266b27920d42269ebc761e07636e3c/processed-46b7c7dd-4bca-4d1c-955a-7a8d27fbf6d8.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/63266b27920d42269ebc761e07636e3c/processed-46b7c7dd-4bca-4d1c-955a-7a8d27fbf6d8.jpg?mode=crop&amp;width=640 640w, /contentassets/63266b27920d42269ebc761e07636e3c/processed-46b7c7dd-4bca-4d1c-955a-7a8d27fbf6d8.jpg?mode=crop&amp;width=854 854w, /contentassets/63266b27920d42269ebc761e07636e3c/processed-46b7c7dd-4bca-4d1c-955a-7a8d27fbf6d8.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Sunanda Chhetri, Irina Gutche, Laura Belot and Lorene Gonnin enjoing the poster session at the cryoNET Symposium.</p><span class="bildPhotografer"><span class="photo">Image</span>Sara Sandin</span></div></div><p>Bernt Eric Uhlin, professor at Ume&aring; University who has been involved with cryoNET since its inception, gave a thoughtful reflection:</p><p class="quote-center">I am now retired, but why should I give up my passion?</p><p>His remarks captured the core spirit of the event, driven by genuine passion for research and collaboration. Whether during the talks or informal coffee breaks, that enthusiasm was clear.</p><p>The hall was filled with thoughtful discussions and meaningful exchanges between peers, mentors, and collaborators. A key highlight was the poster session, where PhD students and Postdocs presented their work. While all contributions were impressive, the organisation team is pleased to congratulate our award winners:</p><ul><li><strong>Adriana Chrenkov&aacute;</strong> &ndash; Understanding sucrose transport in plants</li><li><strong>Bianca Korse</strong> &ndash; Structural basis of GRAF1-mediated membrane tubulation</li><li><strong>Liya Mukhamedova</strong> &ndash; Initial stages of enteroviral infections</li></ul><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="d0851952-2fd1-4c40-ae85-86107fd7179e" data-contentname="cryoNET2025_1">{}</div><p>As with any event, the symposium concluded, leaving a strong sense of progress and optimism for what lies ahead. In 2026, the cryoNET symposium will take place in Copenhagen. The cryoNet committee in Ume&aring; extends our sincere thanks to Aarhus University, the University of Copenhagen, Stockholm University, and Ume&aring; University, as well as to our generous sponsors: the Novo Nordisk Foundation, Knut and Alice Wallenberg Foundation, Wenner-Gren Foundation, Thermo Fisher, UCMR, and MIMS.</p>/en/news/the-nordic-cryonet-symposium_12145845//en/news/molecular-bodyguard-helps-infections-persist_12145023/Researchers at Umeå University have identified a key molecular player that helps bacteria survive the hostile environment inside the body. Their study reveals how the protein RfaH acts as a protective shield for bacterial genes — and points to new strategies for fighting persistent infections. Thu, 16 Oct 2025 12:14:25 +0200<p>&ldquo;The human body is a very stressful place for bacteria,&rdquo; says Kemal Avican research group leader at Department of Molecular Biology and Icelab at Ume&aring; University and leader of the study. &ldquo;During infection, the immune system attacks, nutrients are scarce, and microbes are exposed to bile salts, acids and heat. We looked at how RfaH helps bacteria deal with that stress by turning on the right survival genes at the right time.&rdquo;</p><p>Persistent bacterial infections pose a major challenge in medicine: bacteria can linger in the body long after acute symptoms fade, evading immune defenses and surviving antibiotic treatment. In diseases like tuberculosis, this leads to relapse and makes treatment difficult.</p><h3>Keeps critical genes switched on</h3><p>Using <em>Yersinia pseudotuberculosis</em> as a model bacterium that infects the gut, Kemal Avican and his team showed that RfaH is essential for bacterial persistence.</p><p>RfaH acts like a molecular bodyguard, ensuring transcription&mdash;the step where DNA is copied into a messenger molecule that guides protein production&mdash;runs to completion.</p><p>&ldquo;The protein hops onto the transcription machinery and helps it stay on track so the full set of genes is read to the end. This makes RfaH an anti-terminator &ndash; it prevents the termination of transcription&rdquo;, explains Kemal Avican.</p><p>&ldquo;When we removed RfaH, the bacteria's ability to establish long-term infection dropped dramatically!&rdquo; he adds.</p><h3>Surviving the stress of a hostile environment</h3><p>The researchers found that RfaH production ramps up precisely when bacteria need it most&mdash;in late growth stages and when conditions turn hostile.</p><p>In mouse experiments, the difference was stark: nearly all animals became infected with normal bacteria, but only about one in five became infected when bacteria lacked RfaH. This translated to much higher survival rates among the mice.</p><p>Many bacterial genes are arranged in long stretches called operons. Without RfaH, the cellular machinery that reads these genes can stall or stop prematurely. RfaH prevents this, ensuring bacteria can produce surface structures, secrete toxins, and resist stress from the body's defenses.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/d5012fe72b7f48cb9a0fabe43f3f6fbb/yersinia_pseudotuberculosis_drfah_salt_kemal_avican.png?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d5012fe72b7f48cb9a0fabe43f3f6fbb/yersinia_pseudotuberculosis_drfah_salt_kemal_avican.png?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d5012fe72b7f48cb9a0fabe43f3f6fbb/yersinia_pseudotuberculosis_drfah_salt_kemal_avican.png?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d5012fe72b7f48cb9a0fabe43f3f6fbb/yersinia_pseudotuberculosis_drfah_salt_kemal_avican.png?mode=crop&amp;width=640 640w, /contentassets/d5012fe72b7f48cb9a0fabe43f3f6fbb/yersinia_pseudotuberculosis_drfah_salt_kemal_avican.png?mode=crop&amp;width=854 854w, /contentassets/d5012fe72b7f48cb9a0fabe43f3f6fbb/yersinia_pseudotuberculosis_drfah_salt_kemal_avican.png?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Atomic force microscopy images of Yersinia pseudotuberculosis cells that lack the RfaH protein growing under high salt condition. As a result of not having RfaH, the bacteria have faulty surfaces which cause them to clump together in a stressful, high-salt environment.</p><span class="bildPhotografer"><span class="photo">Image</span>Kemal Avican</span></div></div><p>&nbsp;</p><h3>Insights for future antimicrobial therapies</h3><p>The research revealed that RfaH controls the production of a key component of the surface of bacteria - the O-antigen. Without RfaH, this outer coat becomes defective. But RfaH's influence extends further, activating many &ldquo;downstream&rdquo; genes involved in attachment, movement, and nutrient transport.</p><p>RfaH itself is present in many bacteria, including harmless members of the microbiota. That is why genes influenced by RfAH through activation or signaling - downstream genes - could provide promising new selective targets to stop persistent infections, the researchers say. &nbsp;&nbsp;</p><p>&ldquo;This antimicrobial approach could disarm pathogenic bacteria without disturbing the beneficial ones&rdquo;, says Joram Kiriga Waititu, postdoctoral fellow at Department of Molecular Biology, and first author of the study.</p><p>While <em>Yersinia pseudotuberculosis</em> usually causes an infection in humans that can heal on its own, it serves as a valuable model for gut bacteria that can cause long-term or recurrent disease, such as <em>Escherichia coli</em>, <em>Salmonella</em> and <em>Helicobacter</em>. In this way, the findings could pave the way for new strategies to tackle hard-to-treat gut infections.</p><p>&nbsp;</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="e5e74599-5e42-43a1-8e3d-5a0dec6acbf5" data-contentname="About the study">{}</div>/en/news/molecular-bodyguard-helps-infections-persist_12145023//en/news/new-discovery--bacterial-bubbles-hitchhike-to-reach-the-cell-surface_12145601/Researchers at Umeå University have discovered that the microscopic “bubbles” released by bacteria in our body do not just drift around randomly. Instead, they use the thin protrusions of cells as a transport route to quickly and efficiently reach their target with their contents.Fri, 10 Oct 2025 14:41:18 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/anna_arnqvist_lab_2700_230223_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/anna_arnqvist_lab_2700_230223_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/anna_arnqvist_lab_2700_230223_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/anna_arnqvist_lab_2700_230223_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/anna_arnqvist_lab_2700_230223_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/anna_arnqvist_lab_2700_230223_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Anna Arnqvist is professor at the Department of Medical Biochemistry and Biophysics at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">increases the understanding of how bacteria and cells interact</p><p>&ldquo;This is a mechanism that increases the understanding of how bacteria and cells interact and, by extension, how we understand and fight infections,&rdquo; says Anna Arnqvist, professor at the Department of Medical Biochemistry and Biophysics at Ume&aring; University, who led the study.</p><h2 id="info0" data-magellan-target="info0">Drones with delivery</h2><p>All living cells can release nano-sized fluid-filled structures that resemble &ldquo;bubbles&rdquo;, so-called vesicles. Bacteria also release such vesicles, and despite their small size, they can carry everything from toxins to proteins and DNA that affects how the receiving host cell reacts.</p><div class="mediaflowwrapper bildlink halfwidthsquareleft"><div class="bildImage"><picture><source srcset="/contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/zia_32.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/zia_32.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/zia_32.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/zia_32.jpg?mode=crop&amp;width=640 640w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/zia_32.jpg?mode=crop&amp;width=854 854w, /contentassets/c7dbfe4dff834c15a3ecaf17da2c1d5b/zia_32.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Zia Ur Rehman, a postdoctoral fellow in Anna Arnqvist's group when the study was conducted. He is now a researcher at Kohat University in Pakistan</p><span class="bildPhotografer"><span class="photo">Image</span>private</span></div></div><p>&ldquo;The vesicles act as messengers between each other and to cells, much like tiny drones that deliver their content,&rdquo; explains Zia Ur Rehman, first author. He was postdoctoral fellow at the Department of Medichal Biochemistry and Biophysics at Ume&aring; University when the study was carried out.</p><p>While previous research has focused on a better understanding of how cells take up vesicles and what effects they cause, the question of how the vesicles reach the surface of the cell body where the uptake occurs has remained unanswered.</p><h2 id="info1" data-magellan-target="info1">Not moving randomly</h2><p>The new study shows that vesicles near host cells do not just drift around randomly. Instead, they hitchhike on thin, hair-like protrusions on the cell surface, called filopodia. Filopodia are rich in actin proteins and play important roles in cell movement, contraction and sensing of the environment. Anna Arnqvist and her colleagues discovered that vesicles utilize filopodia either by "surfing" along them, much like sliding down a railing, or by being actively pulled inward when the filopodia contract.</p><p>This mode of transport efficiently captures vesicles from the surrounding environment and moves them from the outer edge of the cell to the cell body, where they can internalize and thereby deliver their contents to the host cell.</p><p>Using advanced high-resolution microscopy techniques, the team was able to observe vesicles interacting with filopodia in real time and even measure their speed as they surfed forward or were pulled inward.</p><p>&ldquo;The speed when they surfed forward was an average of 1 nanometer per second. When they were pulled inward, it was faster, an average of 30 nanometers per second, which means it moved about its own length in one to two seconds,&rdquo; says Zia Ur Rehman.</p><h2 id="info2" data-magellan-target="info2">Universal strategy in bacteria</h2><p>&ldquo;Importantly, we saw that the vesicles use the same transport mechanism regardless of which bacterium the vesicles came from, or which tissue the recipient cells belonged to. This suggests that this is a universal strategy that bacteria use,&rdquo; says Anna Arnqvist.</p><p>Because vesicles mimic the surface of their parent bacteria and carry a wide range of molecules, they can affect host cells in many ways. In addition to delivering harmful substances, the vesicles can act as "decoys" to protect bacteria from attack by the immune system.</p><h2 id="info3" data-magellan-target="info3">Preventing and treating infections</h2><p>Since bacterial vesicles already play a key role in infection biology medicine, for example as delivery systems for drugs or vaccines, this study provides important new knowledge about the very first contact with the host cell.</p><p>&ldquo;Our long-term goal with the research is to understand how bacterial vesicles hijack host cells and translate this knowledge into new methods that can prevent or treat infections,&rdquo; says Anna Arnqvist.</p><p>The study has been published in the Journal of Extracellular Vesicles. It has been funded by the Swedish Cancer Society. The analyses were carried out at the Biochemical Imaging Centre Ume&aring; (BICU) and Ume&aring; Centre for Electron Microcopy (UCEM) at Ume&aring; University.</p>/en/news/new-discovery--bacterial-bubbles-hitchhike-to-reach-the-cell-surface_12145601//en/news/abisko-stay-strengthens-research-on-digital-statehood_12143605/For Dr. Michel Rouleau-Dick, three days in Abisko meant more than access to scientific resources—it was also his first encounter with the Arctic landscape, which will shape his research and his life in the North.Tue, 07 Oct 2025 15:58:59 +0200<h2 id="info0" data-magellan-target="info0">Advancing research on digital statehood</h2><p>From 22 to 25 September, Dr. Michel Rouleau-Dick, postdoctoral fellow at the Centre for Transdisciplinary AI and newly appointed Arctic Six Fellow, spent three days at the Abisko Scientific Research Station to develop his research on digital statehood and multi-layered sovereignty. During the visit, he took advantage of the station&rsquo;s extensive library resources, which provided unique materials to enhance and refine his project.</p><h2 id="info1" data-magellan-target="info1">Connecting with the Arctic environment</h2><p>This stay above the Arctic Circle also allowed Dr. Rouleau-Dick with the chance to familiarise himself with the region, as he only recently moved to the North earlier this year. Besides the scientific work, the Arctic landscape itself became a source of inspiration. An enthusiastic amateur photographer, he explored the area and captured the dramatic seasonal change&mdash;from vibrant birch forests in yellow and orange to the snow-covered peaks that surround the station.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="a3226d7c-8c15-4377-9234-a633bb90aeb0" data-contentname="BILD TOP">{}</div><p class="quote-center">Spending time in Abisko has provided me with not only access to exceptional scientific resources but also a deeper connection to the Arctic environment.</p><p>Reflecting on his experience, Dr. Rouleau-Dick noted:</p><p>"Spending time in Abisko has provided me with not only access to exceptional scientific resources but also a deeper connection to the Arctic environment. Experiencing the landscape firsthand adds a new dimension to my research and reinforces my commitment to exploring the complexities of sovereignty in this region."</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="087ddb4c-72d6-4b34-bea9-57b2c2b2d2ec" data-contentname="BILD Abisko">{}</div><h2 id="info2" data-magellan-target="info2">Engaging with ongoing research</h2><p>During his visit, Dr. Rouleau-Dick also attended a lecture by Keith Larson, Director of the Arctic Centre, who shared insights from his long-term research on permafrost thaw. This project, which involves collaborations with high school students in collecting soil samples, demonstrates how Arctic research combines advanced science with local participation.</p><h2 id="info3" data-magellan-target="info3">Looking ahead</h2><p>Returning from Abisko, Dr. Rouleau-Dick brings not only valuable academic insights but also a personal connection to the Arctic environment that will influence his future work. His time at the research station marks a significant step in anchoring his project in the region's realities, blending scholarly investigation with the firsthand experience of the North.</p>/en/news/abisko-stay-strengthens-research-on-digital-statehood_12143605//en/news/when-listeria-bacteria-go-to-fine-dining_12144793/Jörgen Johansson, professor of molecular biology at Umeå University, has studied the Listeria bacteria for 25 years. He is following the outbreak at a top restaurant in Stockholm this week with great interest. We ask him five curious questions:Fri, 03 Oct 2025 11:01:18 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/ee5557ec51cb4204948951ba39c5df2a/dag1_mg_07083.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/dag1_mg_07083.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/dag1_mg_07083.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ee5557ec51cb4204948951ba39c5df2a/dag1_mg_07083.jpg?mode=crop&amp;width=640 640w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/dag1_mg_07083.jpg?mode=crop&amp;width=854 854w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/dag1_mg_07083.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Listeria can grow on agar plates at incredibly low temperatures.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Eva-Maria Diehl</span></div></div><p class="quote-center">For a healthy individual, it takes an incredible number of bacteria &ndash; several billion! &ndash; to get really sick</p><h2 id="info0" data-magellan-target="info0">How serious is the current outbreak in Stockholm, and what are you following particularly closely in its development?</h2><p>&ldquo;The outbreak is serious because it has affected so many healthy people in a short period of time. Normally, people who have some form of weakened immune system are affected, such as pregnant women, the elderly and cancer patients. It is also remarkable that it has happened so quickly, from some of those involved, getting the infection to becoming seriously ill."</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/ee5557ec51cb4204948951ba39c5df2a/jorgen_johansson_bild.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/jorgen_johansson_bild.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/jorgen_johansson_bild.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ee5557ec51cb4204948951ba39c5df2a/jorgen_johansson_bild.jpg?mode=crop&amp;width=640 640w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/jorgen_johansson_bild.jpg?mode=crop&amp;width=854 854w, /contentassets/ee5557ec51cb4204948951ba39c5df2a/jorgen_johansson_bild.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>J&ouml;rgen Johansson is professor at the Department of Molecular Biology at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>privat</span></div></div><h2 id="info1" data-magellan-target="info1">You have been researching the listeria bacteria for over two decades &ndash; what makes it so fascinating from a scientific perspective?</h2><p>&ldquo;Listeria is a bit like Dr. Jekyll and Mr. Hyde, as it can live in the soil and multiply without any problems. Sometimes, however, it can enter the food chain, usually through dairy production or in fishery products, and then become an extremely aggressive and "successful" pathogen that can have a mortality rate of up to 30 percent.&rdquo;</p><h2 id="info2" data-magellan-target="info2">What do we know today about how Listeria manages to enter the human body and cause disease?</h2><p>&ldquo;Listeria is probably one of the bacteria that we know best about how it causes disease and how it interacts with the human cell. The bacterium enters the body by eating food contaminated with Listeria and enters the intestinal epithelial layer.&rdquo;</p><p>&ldquo;For a healthy individual, it takes an incredible number of bacteria &ndash; several billion! &ndash; to get really sick. In those cases, the bacteria make their way from the epithelial cells into the bloodstream where they usually spread to the liver and spleen and multiply. In a healthy individual, the immune system takes care of the bacteria, but if you have a weakened immune system, the bacteria can spread into the blood and cause sepsis or get into the brain and cause meningitis. In pregnant women, the bacteria can enter through the amniotic sac to the fetus. The later stages of the infection have a mortality rate of up to 30 percent.&rdquo;</p><h2 id="info3" data-magellan-target="info3">Is there something about Listeria in particular that makes it extra difficult to control in food handling?</h2><p>&ldquo;Listeria can grow at incredibly low temperatures. In my lab, for example, we have grown the bacteria on agar plates that we have placed on ice. Even if you buy a food with few Listeria bacteria, its ability to grow at low temperatures means that after a week or so you can have enormous amounts of bacteria in the food. In addition, it can withstand very high salt concentrations. I usually use Paris as an example where I was a postdoctoral fellow at the Pasteur Institute. Just a few hundred meters away, on certain days you can buy cheese at a food market that is made from unpasteurized cheese. Even if there are few bacteria when you buy it, there can be an incredible number of bacteria if you take it home and eat it after a few weeks.&rdquo;</p><h2 id="info4" data-magellan-target="info4">What about Listeria and antibiotic resistance?</h2><p>&ldquo;Listeria is still (mostly) susceptible to antibiotics. However, it can be good to be prepared for the fact that it will at some point become antibiotic resistant, which is true for all pathogenic bacteria.&rdquo;</p>/en/news/when-listeria-bacteria-go-to-fine-dining_12144793//en/news/we-must-protect-both-security-and-freedom_12144314/How can society respond to a growing terrorist threat without undermining democracy? This question is at the heart of Susanna Bellander's doctoral thesis at Umeå University. "We must stop viewing security and freedom as a zero-sum game. In times of unrest, we need to protect both, simultaneously," says Susanna Bellander, doctoral student at Unit for Police Work. Tue, 30 Sep 2025 13:51:36 +0200<p>Susanna Bellander has been a police officer for 15 years and has worked as an investigator of serious crimes and intelligence operations, as well as with terrorism and counter-terrorism, both operationally and strategically. In her research, she has combined document analysis, interviews with police employees in 2022 and 2025, and a national survey study following the terrorist attack in Stockholm in 2017.</p><p>The results show that security measures are often prioritised at the expense of preventive efforts and democracy-building work. According to Susanna Bellander, there is a clear imbalance, with reactive measures being given better conditions for implementation than democracy-building efforts.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/5b247777fa044554a1e677c137cc9e5e/susanna_bellander2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/5b247777fa044554a1e677c137cc9e5e/susanna_bellander2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/5b247777fa044554a1e677c137cc9e5e/susanna_bellander2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/5b247777fa044554a1e677c137cc9e5e/susanna_bellander2.jpg?mode=crop&amp;width=640 640w, /contentassets/5b247777fa044554a1e677c137cc9e5e/susanna_bellander2.jpg?mode=crop&amp;width=854 854w, /contentassets/5b247777fa044554a1e677c137cc9e5e/susanna_bellander2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Susanna Bellander, affiliated as doctoral student at Unit of Police Work. Photo: Sophia Nilsson S&ouml;dert&ouml;rns h&ouml;gskola.</p></div></div><p>"As a police officer, I have seen the need for strong measures in critical situations. As a researcher, I have learned that long-term security requires something more &ndash; a constant awareness of what we risk losing if democracy is compromised in the name of protection," says Susanna Bellander.</p><h3>Vulnerable members of society are hit harder</h3><p>Research also shows that people with a low quality of life, or a weak sense of belonging to Swedish society, are hit harder by fear and reduced trust in the wake of terrorist attacks. This points to the need for inclusive strategies that strengthen the resilience of society as a whole &ndash; not just protect against threats. The thesis argues that effective counter-terrorism must be proportionate, responsible and integrated &ndash; with a focus on both protection and rights.</p><p>Susanna Bellander has defended her thesis at the Faculty of Medicine, Department of Epidemiology and Global Health, which she believes is obvious:</p><p>"Terrorism has a profound impact on people's health &ndash; from direct victims to emergency services personnel, witnesses and society as a whole. Counterterrorism also has extensive health aspects that are important to study."</p>/en/news/we-must-protect-both-security-and-freedom_12144314//en/news/anne-bridges-virology-and-cardiology-as-new-myocarditis-research-emerges_12142115/Myocarditis is a serious inflammation of the heart muscle that can hit young, healthy people hard—and without warning. In the worst cases, it can lead to heart failure or sudden cardiac death. Researcher Anne Tuiskunen Bäck is working to close key knowledge gaps in diagnostics, risk assessment, and follow-up of patients.Mon, 29 Sep 2025 12:33:02 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/c00ba5c48dc341d3a9ec62440fdb461c/anne_och_amina2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/anne_och_amina2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/anne_och_amina2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c00ba5c48dc341d3a9ec62440fdb461c/anne_och_amina2.jpg?mode=crop&amp;width=640 640w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/anne_och_amina2.jpg?mode=crop&amp;width=854 854w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/anne_och_amina2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Researcher Anne Tuiskunen B&auml;ck and her PhD Amina Hayat.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p class="quote-center">it is very important to obtain new knowledge</p><p>&ldquo;It is very important to obtain new knowledge, so that we can more easily make the correct diagnosis and find risk groups. Most people with myocarditis recover on their own, but some patients develop heart complications. If we can identify these patients early, we could implement preventive measures,&rdquo; says Anne Tuiskunen B&auml;ck, a specialist in cardiology at Norrland University Hospital and a researcher at Ume&aring; University.</p><h2 id="info0" data-magellan-target="info0">Viruses most common cause</h2><p>You often hear that you should avoid exercise when you have a cold &ndash; and there is a good reason: the risk of myocarditis. In the Western world, myocarditis is most often caused by viruses, but bacteria, fungi, parasites, side effects of certain cancer drugs or autoimmune diseases can also be behind it. In the disease, the immune system overreacts and attacks the heart muscle, which can impair the heart's ability to pump blood around the body.</p><p>&ldquo;No specific treatments exist, and in most cases, the disease is mild and transient. We usually let go of patients completely when the myocarditis appears to have healed and all tests have normalized. We urge them to avoid physical activity for a couple of months, which can be difficult, especially for younger people, to follow,&rdquo; says Anne Tuiskunen B&auml;ck.</p><p>However, myocarditis can cause long-term complications and, in some cases, become chronic if the inflammation does not heal completely. Over time, the heart loses its elasticity and enlarges, as the heart wall thins when heart muscle cells are replaced by scar tissue. In the most severe cases, this can lead to terminal heart failure, where a heart transplant becomes necessary to survive. Today, there is a lack of knowledge about how to identify early on which patients are at risk of being affected.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/c00ba5c48dc341d3a9ec62440fdb461c/hjartbild_14.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/hjartbild_14.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/hjartbild_14.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c00ba5c48dc341d3a9ec62440fdb461c/hjartbild_14.jpg?mode=crop&amp;width=640 640w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/hjartbild_14.jpg?mode=crop&amp;width=854 854w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/hjartbild_14.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Patients who come to the hospital experience symptoms such as unexplained chest pain, shortness of breath and palpitations.</p><span class="bildPhotografer"><span class="photo">Image</span>John&eacute;r bildbyr&aring;</span></div></div><h2 id="info1" data-magellan-target="info1">Lack of research</h2><p>Anne Tuiskunen B&auml;ck got the idea for her research project two years ago when her clinic director asked her to look through the clinical management plan for myocarditis patients, which is based on the European Society of Cardiology guidelines.</p><p>&ldquo;I was surprised; the guidelines were from 2013! Unlike the guidelines for myocardial infarction, which are updated every five years. The lack of updated guidelines is due to the absence of large clinical studies on myocarditis,&rdquo; says Anne Tuiskunen B&auml;ck.</p><p>In the scientific literature, Anne saw a clear lack of research on how infections affect myocarditis. She also reacted to the lack of communication between virology and cardiology &ndash; two fields that would benefit from collaborating more. That is where the interest was sparked.</p><p>&ldquo;I got involved in how we could improve the routines for long-term follow-up, to identify patients at risk of developing severe cardiac complications and also to look for better tools for diagnosing myocarditis,&rdquo; says Anne.</p><h2 id="info2" data-magellan-target="info2">Follow-up for 25 years</h2><p>Last year, Anne Tuiskunen B&auml;ck began the extensive work of preparing the clinical study &ndash; a process that requires careful planning and extensive administration. Since the study involves data from humans, approval is required from the Swedish Ethics Review Authority, an authority for all clinical research in Sweden. Anne eventually received permission to follow newly diagnosed patients until the year 2050 and previous cases of myocarditis in V&auml;sterbotten since 2009.</p><p>The study is now operating at a high level of activity. The newly diagnosed patients (the acute patient group) submit repeated samples during the days they are hospitalized and then at return visits. The other patient group who has had myocarditis previously submits a blood sample via their local health care centre.</p><p>&ldquo;We will follow each patient for a really long time through medical records regarding their heart health and compare with what we see in their samples to find new diagnostic and risk markers.&rdquo;</p><p>Anne Tuiskunen B&auml;ck has recently been awarded 500,000 kronor from the Norrl&auml;ndska Hj&auml;rtfonden for the research project, an addition that gives the work a new boost. She has recruited Amina Hayat, a specialist in cardiology, as a doctoral student. Amina is responsible, among other things, for contacting new participants in the study. In the Autumn, the research group will be further strengthened when two postdoctoral fellows join to work on the project.</p><p>&ldquo;The turnout of participants is overwhelming. One 20-year-old even said that it felt like a privilege to be part of the study, that makes it extra fun!&rdquo;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/c00ba5c48dc341d3a9ec62440fdb461c/biomedicinsk-analytiker_7295-250513-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/biomedicinsk-analytiker_7295-250513-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/biomedicinsk-analytiker_7295-250513-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c00ba5c48dc341d3a9ec62440fdb461c/biomedicinsk-analytiker_7295-250513-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/biomedicinsk-analytiker_7295-250513-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/c00ba5c48dc341d3a9ec62440fdb461c/biomedicinsk-analytiker_7295-250513-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>The patients being followed are asked to provide blood samples. <span class="photo" style="color: #666666; font-size: 0.66667rem; text-wrap-mode: nowrap;">Image</span><span style="color: #666666; font-size: 0.66667rem; text-wrap-mode: nowrap;">Mattias Pettersson</span></p></div></div><h2 id="info3" data-magellan-target="info3">New biomarkers for diagnosis</h2><p>It is difficult to diagnose suspected myocarditis. The doctor performs a physical examination and looks at the patient's symptoms, takes blood samples, an ECG, a cardiac ultrasound and performs an MRI scan of the heart. Early biopsy &ndash; a tissue sample from the heart &ndash; is the most reliable way to make a diagnosis but is also fraught with several limitations and uncertainties.</p><p>&ldquo;For this reason, we do it extremely rarely. If the patient is not terminally ill with their heart disease, there is very little benefit in retrieving a biopsy from the heart. That is the reasoning.&rdquo;</p><p>As a result, the diagnosis is often based on a probability assessment rather than a definitive conclusion. The fact that many cases probably also go under the radar is another reason for the lack of reliable statistics on how many people are affected by myocarditis in Sweden each year.</p><p>The second part of the project focuses on finding new biomarkers for diagnosing myocarditis. Anne Tuiskunen B&auml;ck is investigating whether a blood test can replace tissue tests. She and her colleagues analyse lab samples from the patients, including using metagenomics to find out which virus is involved, and also map the patients' genome to see if genetic factors increase the risk. In collaboration with other research groups, they will study the immune response and metabolomics of the patients at a later stage.</p><h2 id="info4" data-magellan-target="info4">Cardiology and virology in combination</h2><p>This is a typical example of a translational project, which means that basic research solves questions raised in the clinic. In this way, Anne Tuiskunen B&auml;ck uses both her knowledge in virology and her clinical competence as a medical doctor. The research is also interdisciplinary and spans virology, cardiology and genetics.</p><p>The study is extensive. It involves several clinics, many colleagues and patients of all ages, from infants to the elderly. There are also discussions about scaling up the study to other hospitals in Sweden.</p><p>Cardiology is a dynamic and research-intensive field that naturally interacts with virology, notes Anne Tuiskunen B&auml;ck.</p><p>&ldquo;It is both exciting and fun to combine two fields. Having one foot in virology and one in cardiology works great &ndash; and feels innovative.&rdquo;</p>/en/news/anne-bridges-virology-and-cardiology-as-new-myocarditis-research-emerges_12142115//en/news/when-trees-become-co-actors_12142895/A Western diet, rich in fat and poor in fibre, can weaken the gut protective mucosa and increase the risk of infection and inflammation. Now, Umeå researchers have identified a milk-derived molecule that can significantly strengthen the function of the intestinal mucosa and pave the way for new dietary strategies.Thu, 25 Sep 2025 14:08:59 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/901353848d8741eba0f0469b1fa4ad09/4_img_3433_kopiera3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/901353848d8741eba0f0469b1fa4ad09/4_img_3433_kopiera3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/901353848d8741eba0f0469b1fa4ad09/4_img_3433_kopiera3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/901353848d8741eba0f0469b1fa4ad09/4_img_3433_kopiera3.jpg?mode=crop&amp;width=640 640w, /contentassets/901353848d8741eba0f0469b1fa4ad09/4_img_3433_kopiera3.jpg?mode=crop&amp;width=854 854w, /contentassets/901353848d8741eba0f0469b1fa4ad09/4_img_3433_kopiera3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Researcher Bj&ouml;rn Schr&ouml;der and postdoctoral fellow Supapit Wongkuna have identified a milk-based molecule that can significantly strengthen the function of the gut mucosa.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p class="quote-center">the molecule can act as as a decoy substrate for mucus-degrading bacteria</p><p>&ldquo;Our study shows that the milk-derived molecule can act as as a decoy substrate for mucus-degrading bacteria, which helps to protect the host's mucus barrier even in the fibre-deficient conditions, says researcher Bj&ouml;rn Schr&ouml;der, Department of Molecular Biology at Ume&aring; University, who has led the study.</p><h2 id="info0" data-magellan-target="info0">Positive effects on the gut</h2><p>The molecule in question, casein glycomacropeptide (CGMP), is a protein with sugar molecules that occurs naturally in cheese whey. In studies on mice fed on a "Western diet", Bj&ouml;rn Schr&ouml;der and his team were able to show that CGMP has several positive effects on the gut. It stimulated the production of mucus, made the gut wall less permeable and favoured the growth of beneficial bacteria &ndash; especially Bifidobacterium.</p><p>The effects depended on how much sugar was attached to the molecule, a modification called sialylation. The researchers also saw that CGMP increased the amount of small fatty acids in the gut, especially propionate. This fatty acid is known to strengthen the gut protective barrier and contribute to a healthy mucosa.</p><p>&ldquo;This is a clear example of how something we eat can positively affect the interaction between the body and gut bacteria,&rdquo; says Supapit Wongkuna, postdoctoral fellow at the Department of Molecular Biology at Ume&aring; University, and first author of the study.</p><h2 id="info1" data-magellan-target="info1">Crucial collaboration with industry</h2><p>The study was conducted in collaboration with Arla Foods Ingredients in Denmark, a global player in dairy-based ingredients. The collaboration was crucial for the researchers to have access to tailor-made CGMP fractions with varying levels of sialylation.</p><p>For Arla, the collaboration not only means a contribution to research, but also the opportunity to further develop its ingredients based on scientific results.</p><p>&ldquo;We are proud to be able to support research that investigates the health-promoting potential of proteins in whey. This study shows that CGMP has value far beyond its traditional uses,&rdquo; says Ann Bj&oslash;rnshave, project manager at Arla Foods Ingredients.</p><h2 id="info2" data-magellan-target="info2">Prebiotics for gut health</h2><p>The research highlights the possibility of reusing dairy compounds as a prebiotic food supplement.</p><p>&ldquo;We see a very promising opportunity to not only counteract the negative effects of a Western diet, but also actively promote gut health and well-being&rdquo;, says Bj&ouml;rn Schr&ouml;der</p><p>The results are published in the scientific journal Food Research International.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/901353848d8741eba0f0469b1fa4ad09/2_img_3492_besk2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/901353848d8741eba0f0469b1fa4ad09/2_img_3492_besk2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/901353848d8741eba0f0469b1fa4ad09/2_img_3492_besk2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/901353848d8741eba0f0469b1fa4ad09/2_img_3492_besk2.jpg?mode=crop&amp;width=640 640w, /contentassets/901353848d8741eba0f0469b1fa4ad09/2_img_3492_besk2.jpg?mode=crop&amp;width=854 854w, /contentassets/901353848d8741eba0f0469b1fa4ad09/2_img_3492_besk2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Supapit Wongkuna and Bj&ouml;rn Schr&ouml;der hope for a future new prebiotic.</p><span class="bildPhotografer"><span class="photo">Image</span>[Ingrid S&ouml;derbergh]</span></div></div>/en/news/milk-derived-molecule-strengthens-gut-health-even-with-unhealthy-diet_12142933//en/news/arctic-and-sami-research-in-focus-as-university-of-northern-british-columbia-visited-umea-university_12139837/Dr. Paula Wood-Adams, Vice President for Research and Innovation at the University of Northern British Columbia (UNBC), visited Umeå University on 10 September to learn more about current Arctic and Sámi research and to explore potential areas for collaboration.Thu, 18 Sep 2025 13:28:44 +0200<p class="quote-center">The Arctic Centre aims to facilitate meetings [&hellip;] and promote more sustainable and interconnected Arctic research.</p><h2 id="info0" data-magellan-target="info0">Arctic research in focus</h2><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="158ae3ec-c05b-4031-a3b5-34f4f41d1727" data-contentname="BILD UNBC SO">{}</div><p>Throughout the day, Arctic Centre-associated researchers presented projects ranging from the impacts of climate change on ecosystems to health systems in sparsely populated areas, as well as issues related to tourism and security. These insights provided a valuable basis for discussing how international partnerships can strengthen knowledge development for the benefit of remote and Arctic communities.</p><p>"The Arctic Centre aims to facilitate meetings like this, where representatives from other universities can connect with our researchers, find inspiration, and establish the foundation for future collaboration. The visit from UNBC highlights the importance of cross-border dialogue and knowledge exchange, utilising existing platforms such as UArctic to promote more sustainable and interconnected Arctic research," says Simon Oja, Deputy Director of the Arctic Centre at Ume&aring; University.</p><h2 id="info1" data-magellan-target="info1">S&aacute;mi and Indigenous research deepens understanding&nbsp;</h2><p>The V&aacute;rdduo &ndash; Centre for S&aacute;mi Research &ndash; presented its activities and highlighted the importance of Indigenous knowledge in Arctic research. Topics of language, identity, and sustainable community development and cultural revitalisation were discussed, alongside new research that offers a deeper understanding of the historical and contemporary circumstances of S&aacute;mi communities. These perspectives collectively emphasise the vital role of S&aacute;mi research in developing more inclusive and socially relevant Arctic knowledge.</p><p class="quote-center">S&aacute;mi research is a crucial aspect of Ume&aring; University&rsquo;s Arctic profile.</p><p>"S&aacute;mi research is a crucial aspect of Ume&aring; University&rsquo;s Arctic profile. By incorporating Indigenous perspectives, we enhance the research and its societal relevance. International collaborations, such as the one with UNBC, create opportunities for valuable comparisons and mutual learning between Indigenous peoples in different regions of the world," says Kristina Sehlin MacNeil, Deputy Director of V&aacute;rdduo &ndash; Centre for S&aacute;mi Research at Ume&aring; University.</p><h2 id="info2" data-magellan-target="info2">UArctic as a key to collaboration</h2><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="4095e446-bd9a-4f45-aab2-fefec893f470" data-contentname="BILD UNBC PWA">{}</div><p>Discussions included the University of the Arctic (UArctic), an international network of almost 200 member institutions, as a key platform for future collaboration. Through UArctic, researchers at Ume&aring; University and UNBC can build on existing partnerships through thematic networks and the North2North mobility program, while also creating new initiatives in education and research.<br>The visit showcased the diverse research at Ume&aring; University through the Arctic Centre, V&aacute;rdduo &ndash; Centre for S&aacute;mi Research, and others. The presentations provided UNBC&rsquo;s representative with insights into the various perspectives shaping today&rsquo;s Arctic research landscape. The programme concluded with a meeting involving Deputy Vice-Chancellor Patrik Danielsson, Vice-Chancellor&rsquo;s Adviser Thomas Olofsson, and Helena Gradin, Assistant Head of Division at the International Office.</p>/en/news/arctic-and-sami-research-in-focus-as-university-of-northern-british-columbia-visited-umea-university_12139837//en/news/carlos-wins-european-best-poster-prize-in-great-competition_12139856/Winning a poster award at an academic conference validates your research, showcases communication skills, and boosts future academic prospects. Carlos Hernandez Ortego, doctoral student at Umeå University, returned from Europe’s biggest conference in microbiology winning a prize among 1200 posters. We ask 5 curious questions how he managed to achieve this.Fri, 12 Sep 2025 16:45:21 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/9f1f8a8f82ea4304aaeadcb42187d6b1/carlos_besk.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/9f1f8a8f82ea4304aaeadcb42187d6b1/carlos_besk.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/9f1f8a8f82ea4304aaeadcb42187d6b1/carlos_besk.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/9f1f8a8f82ea4304aaeadcb42187d6b1/carlos_besk.jpg?mode=crop&amp;width=640 640w, /contentassets/9f1f8a8f82ea4304aaeadcb42187d6b1/carlos_besk.jpg?mode=crop&amp;width=854 854w, /contentassets/9f1f8a8f82ea4304aaeadcb42187d6b1/carlos_besk.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>The FEMS MICRO 2025 poster prize was awarded to Carlos Hern&aacute;ndez-Ortego, PhD at the Department of Molecular Biology at Ume&aring; University, by the FEMS journal microLife. Pictured left, Dr Clare Taylor presenting the award.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Liza Holiarchuk</span></div></div><p class="quote-center">I had never won a poster prize before</p><h2 id="info0" data-magellan-target="info0">How does it feel?</h2><p>&ldquo;When they first announced the winners in the morning of the last day via email I did not believe my eyes, but I was happy! I did see a sticker on my poster from one of the FEMS journals when I went to remove my poster, apparently, they are interested in publishing our data. This was a good indication, but I still did not expect to get a prize. There were more than 1200 posters, and I had never won a poster prize before, so I thought the chances would be minimal.&rdquo;</p><p>&ldquo;They gave seven prices; one awarded for each of the FEMS different scientific journals. Mine was FEMS microLife.&rdquo;</p><h2 id="info1" data-magellan-target="info1">What was your poster about?</h2><p>&ldquo;In my poster I tried to summarise my PhD project that I have been working on for the last four years. It is about our discovery of how intestinal bacteria can degrade extracellular ATP, a powerful proinflammatory molecule. We discovered the enzymes responsible for the eATP degradation pathway, and we characterised exactly how they degrade eATP to hypoxanthine. We also showed the implications using mutants and cell cultures. Currently we are also expanding to in vivo mouse models."</p><p>"I think people enjoyed the story because it is well structured and an (almost) completed story. People can easily see the gap in the current knowledge about the topic, and how we filled it with our data. It is also a rather basic research topic, focused on basic knowledge of bacterial physiology, which can attract people from all different fields, in contrast to more specific, more applied kind of science. Our data has potential implications in health, natural environment or industry. Importantly, we have a lot of data on the topic, so most of the questions and concerns of the jury could be addressed.&ldquo;</p><h2 id="info2" data-magellan-target="info2">How have you worked to visualize and communicate your research on the poster?</h2><p>&ldquo;I made my poster during the course <em>Visualize your Science</em>, a renowned science communication course in Sweden. They are quite successful at helping people generate high-quality posters. The course was very helpful in providing me feedback and advice. In general, I would say that the best way to go when creating a poster is to ask for feedback from a lot of different people. They will always have some useful input on what is unclear or not looking good."</p><p>"Since my project has a lot of data, the decision of what to include and what to leave out on the poster was a big challenge. I tried minimizing the amount of &ldquo;noise&rdquo;, keeping things simple, not saturating the poster with data. When you spend half a year to generate a figure, you of course want to add it, but maybe it is detrimental for the whole flow or understanding of the poster. To be able to <em>kill your darlings</em> is important.&rdquo;</p><h2 id="info3" data-magellan-target="info3">What do you think stood out in your poster?</h2><p>&ldquo;Most posters nowadays have beautiful layout and nice colours. Young researchers are good at those things.&nbsp; For me, I had to learn design by force, attending courses and looking for examples. I think the winning point was actually my presentation of the poster. Presenting has always felt natural to me. I think the way I explain the data, very simplified and trying to avoid overcomplicated experiments or terms made people engaged and appreciating the poster a lot more. Additionally, not learning what you are going to say by heart and improvise instead, helps to keep things very casual, so people are more relaxed and feel more encouraged to ask questions."</p><p>"I did talk to<em> a lot</em> of people during the poster presentation, and it looked like most of them were interested.&rdquo;</p><h2 id="info4" data-magellan-target="info4">What was the biggest benefit for you with presenting a poster about your research?</h2><p>&ldquo;I got to know some research teams that work on similar things as my group at Ume&aring; University and we had interesting discussions. I also exchange contact information with them; in case we want to do a collaborative work together. I had long discussions with PIs and journal editors who were interested. To summarise, it was a great opportunity to make new contacts and find new possible collaborators."</p>/en/news/carlos-wins-european-best-poster-prize-in-great-competition_12139856//en/news/intimate-partner-violence-services-fall-short-for-women-with-disabilities_12139505/Women with disabilities who are exposed to intimate partner violence are doubly affected – both by abuse and by the inadequacy of society's support system. This is shown in a new thesis at Umeå University with recommendations for structural changes.Thu, 11 Sep 2025 11:25:49 +0200<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/67a664f6227c4458941f4d410d46daeb/anyango_catrine_2523_210908_mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/67a664f6227c4458941f4d410d46daeb/anyango_catrine_2523_210908_mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/67a664f6227c4458941f4d410d46daeb/anyango_catrine_2523_210908_mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/67a664f6227c4458941f4d410d46daeb/anyango_catrine_2523_210908_mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/67a664f6227c4458941f4d410d46daeb/anyango_catrine_2523_210908_mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/67a664f6227c4458941f4d410d46daeb/anyango_catrine_2523_210908_mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Cartrine Anyango, doctoral student at the Department of Epidemiology and Global Health. <span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Mattias Pettersson</span></p></div></div><p>"Even if there is support, in practice it is not available to everyone. Coordination, inclusion and humanity are needed to build a 'bridge' from violence to safety, justice and dignity," says Cartrine Anyango.</p><p class="quote-left">a bridge from violence to safety</p><p>In her doctoral thesis in public health, Cartrine Anyango has interviewed eleven women with disabilities who have suffered from violence in close relationships, interviewed 18 professionals in support institutions, police, social services, health care and women's shelters and conducted a survey with 1,151 professionals in those institutions.</p><p>The interviewed women described how they had been exposed to several types of violence, both physical and psychological, sexual, digital and financial. It was also about actions directly linked to their disability, such as degrading comments or that help was withheld. It was not only a partner who was responsible for the violence, it could also come from family members, colleagues or assistants.</p><p>Psychological violence was particularly difficult, something that the women felt was often not taken seriously and which could continue even after a relationship ended, for example in the case of shared custody or financial dependence. The women felt unseen and misunderstood when they sought help for abuse.</p><p>Many of the providers stated that they had met women with disabilities who had been subjected to violence. But more than half did not indicate whether they routinely ask women with disabilities about violence. Where &nbsp;disability specific guidelines existed, they were often not followed.</p><p>"Despite the fact that Sweden is a relatively equal welfare country, society's support system can inadvertently exclude this group if their complex and doubly vulnerable situation is not taken into account," says Cartrine Anyango.</p><p>The thesis concludes that structural changes are needed. Psychological violence must be taken seriously, accessibility to support must be ensured, training of those working in support systems needs to take place and be designed in consultation with women who have experienced different types of violence.</p><p><em>Cartrine Anyango grew up in Nakuru, Kenya. She holds a bachelor&rsquo;s degree in Sociology from Maseno university in Kisumu, Kenya and a master&rsquo;s degree in public health from Ume&aring; University.</em></p>/en/news/intimate-partner-violence-services-fall-short-for-women-with-disabilities_12139505//en/news/jan-researches-the-role-of-bacteria-in-periodontal-disease_12138880/Periodontitis is a common but often overlooked disease. Jan Oscarsson at Umeå University is researching how this can be detected early and treated effectively – using cell and molecular biology methods. We ask him five curious questions.Wed, 10 Sep 2025 08:10:21 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/37d082f09b2b43c182e1f61df4efa3b5/jan_pa_labb3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/jan_pa_labb3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/jan_pa_labb3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/37d082f09b2b43c182e1f61df4efa3b5/jan_pa_labb3.jpg?mode=crop&amp;width=640 640w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/jan_pa_labb3.jpg?mode=crop&amp;width=854 854w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/jan_pa_labb3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Jan Oscarsson is a researcher at the Department of Odonthology at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p class="quote-center">These bacteria gradually break down the tissues that hold the teeth in place</p><h2 id="info0" data-magellan-target="info0">What is periodontal disease and what causes the disease?</h2><p>&ldquo;Periodontitis, or gum disease, is a chronic inflammation of the mouth that is initially caused by bacteria. These bacteria gradually break down the tissues that hold the teeth in place. Due to this inflammation, our own osteoclasts ultimately cause the breakdown of jawbone. The disease is widespread worldwide, especially among the elderly, and one of the biggest risk factors is poor oral hygiene.&rdquo;</p><p>&ldquo;When bacteria accumulate around the teeth, the risk of the gums becoming inflamed increases. Over time, an environment is created that is both oxygen-free and rich in proteins &ndash; perfect conditions for certain bacteria in the oral flora to grow and worsen the condition.&rdquo;</p><h2 id="info1" data-magellan-target="info1">What is the research focus in your group?</h2><p>&ldquo;We are studying how bacteria linked to periodontitis can trigger inflammatory processes in the mouth. The focus is both on how the bacteria interact with each other and on identifying genetic markers in particularly aggressive bacterial strains &ndash; something that could improve the possibilities for early diagnosis in the future.&rdquo;</p><p>&ldquo;As model organisms, we use, among others, <em>Aggregatibacter actinomycetemcomitans</em>, a bacterium that is often found in aggressive forms of periodontitis in younger people. We are also investigating <em>Filifactor alocis</em>, a relatively newly discovered possible pathogen in the oral cavity.&rdquo;</p><h2 id="info2" data-magellan-target="info2">What is the dream goal of the research?</h2><p>&ldquo;One of our goals is to find reliable markers that make it possible to identify young people who carry particularly aggressive bacterial strains with a simple saliva sample &ndash; and thus run an increased risk of developing periodontitis at an early stage.&rdquo;</p><p>&ldquo;Another track in the research is about understanding the mechanisms that bacteria use to trigger inflammation. By mapping these processes, we hope to find ways to block them &ndash; without having to kill the bacteria, which is the case with antibiotic treatment.&rdquo;</p><h2 id="info3" data-magellan-target="info3">Tell us about new knowledge you have developed!</h2><p>&ldquo;In a study among young people in V&auml;sterbotten, we found signs that saliva samples may be sufficient to analyse bacteria linked to periodontitis &ndash; a finding that was presented in Mark Lindholm&rsquo;s doctoral thesis. In collaboration with researchers at Karolinska Institutet, we have also identified a previously unknown toxin and possible virulence factor in the bacterium <em>Filifactor alocis</em>. In a broader research collaboration, which also includes colleagues from the Department of Molecular Biology, we have shown that<em> Aggregatibacter actinomycetemcomitans</em> &ndash; a bacterium linked to aggressive forms of periodontitis &ndash; can be killed by its closest relative <em>Aggregatibacter aphrophilus</em> via a so-called type VI secretion system. Since <em>A. aphrophilus</em>, that is also found in the mouth, is not associated with the disease, the question arises: could it contribute to better oral health?&rdquo;</p><h2 id="info4" data-magellan-target="info4">Tell us a little about your background!</h2><p>&ldquo;I grew up in Br&aring;n outside of V&auml;nn&auml;s and completed my undergraduate education at Ume&aring; University, where I also received my PhD in molecular biology in 1999. After a postdoctoral period at Karolinska Institutet, I have been active in odontology at Ume&aring; University for almost two decades.&rdquo;</p><p>&ldquo;My interest in bacterial&ndash;host interactions developed towards the end of my undergraduate education, if I remember correctly. I was lucky enough to delve into the subject as a doctoral student under the supervision of Professor Bernt Eric Uhlin &ndash; and it has remained a central focus of my research ever since.&rdquo;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/37d082f09b2b43c182e1f61df4efa3b5/filifactor_alocis_-_kolonier_pa_blodagarplatta2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/filifactor_alocis_-_kolonier_pa_blodagarplatta2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/filifactor_alocis_-_kolonier_pa_blodagarplatta2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/37d082f09b2b43c182e1f61df4efa3b5/filifactor_alocis_-_kolonier_pa_blodagarplatta2.jpg?mode=crop&amp;width=640 640w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/filifactor_alocis_-_kolonier_pa_blodagarplatta2.jpg?mode=crop&amp;width=854 854w, /contentassets/37d082f09b2b43c182e1f61df4efa3b5/filifactor_alocis_-_kolonier_pa_blodagarplatta2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p><em>Filifactor alocis</em> may be an oral pathogen, but it looks kind and "hearty" when cultivated.</p><span class="bildPhotografer"><span class="photo">Image</span>Jan Oscarsson lab</span></div></div>/en/news/jan-researches-the-role-of-bacteria-in-periodontal-disease_12138880//en/news/global-climate-issues-through-an-arctic-lens_12131710/The visit of Dr. Abdulla Al Mandous, the President of the World Meteorological Organization (WMO), to Umeå on 15 August underscores the global significance of the Arctic Centre. Through long-term strategic initiatives, Umeå University’s Arctic research engages directly with international organisations tackling climate change. The visit reaffirms the university’s role in polar science and shows that WMO regard the Arctic as vital to future climate solutions.Thu, 21 Aug 2025 11:35:55 +0200<p class="quote-center">When the world&rsquo;s leading organisations in climate and meteorology choose to visit Ume&aring; University, it shows that we are more than a strong research environment &ndash; we are a natural partner in the effort for building a sustainable Arctic</p><p>The Arctic plays a pivotal role as the Earth&rsquo;s cooling system, and knowledge connects it far beyond its borders. That WMO President Dr. Abdulla Al Mandous, who also serves as Director General of the United Arab Emirates&rsquo; National Centre of Meteorology, chose to visit the Arctic Centre in Ume&aring; highlights the international relevance and appeal of the university&rsquo;s research and position in the Arctic.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="c4711aa5-3dfe-4db4-8bff-6ef9b96c1b61" data-contentname="PIC WMO">{}</div><h2 id="info0" data-magellan-target="info0">Arctic research in breadth and depth</h2><p>The Deputy Vice-Chancellor for Research, Thomas Olofsson, welcomed the delegation and introduced Ume&aring; University and the Arctic Centre. The programme continued with presentations from researchers showcasing the breadth of Arctic science at Ume&aring;: permafrost hydrology, space weather, ecosystem modelling, and indigenous livelihoods. Key national and European organisations, including the S&aacute;mi Council, the Swedish Polar Research Secretariat, and the European Polar Board, presented other important perspectives.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="f4ed22d7-01d6-4560-94b4-984894013317" data-contentname="PIC WMO audience">{}</div><h2 id="info1" data-magellan-target="info1">International dialogue for a sustainable Arctic</h2><p>The discussions highlighted the need for stronger international collaboration in preparing for major initiatives such as the International Polar Year 2032&ndash;33 and the Emirates Polar Research Programme launch&mdash;a clear signal of the country&rsquo;s ambition to become an active partner in international polar science.</p><p>&ldquo;When the world&rsquo;s leading organisations in climate and meteorology choose to visit Ume&aring; University, it shows that we are more than a strong research environment &ndash; we are a natural partner in the effort for building a sustainable Arctic,&rdquo; says Keith Larson, Director of the Arctic Centre.</p><p>He also emphasises the importance of visits like this:</p><p>&ldquo;By creating meeting places where research connects with society and decision-makers, we can drive forward knowledge that makes a difference. Our ambition is to support societally relevant research and be the primary contact point for those seeking to contribute to a positive Arctic future.&rdquo;</p><p>The visit underlines the global weight of the Arctic issues discussed in Ume&aring; and the university&rsquo;s role in bringing together researchers, decision-makers, and societal actors. Through such encounters, new knowledge gains momentum and becomes a catalyst for change &ndash; in the Arctic and beyond.</p>/en/news/global-climate-issues-through-an-arctic-lens_12131710//en/news/gonorrhoea-is-spreading-and-outsmarting-antibiotics_12131315/The sexually transmitted disease gonorrhoea have increased in the past ten years. No one knows exactly why gonorrhoea is spreading—but experts suspect a mix of better testing and changing sexual habits. At the same time, we face reduced treatment options due to antimicrobial resistance.Wed, 20 Aug 2025 14:41:01 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/cccca061546d43e9bedd877894559fab/tomas_gustafsson.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/cccca061546d43e9bedd877894559fab/tomas_gustafsson.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/cccca061546d43e9bedd877894559fab/tomas_gustafsson.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/cccca061546d43e9bedd877894559fab/tomas_gustafsson.jpg?mode=crop&amp;width=640 640w, /contentassets/cccca061546d43e9bedd877894559fab/tomas_gustafsson.jpg?mode=crop&amp;width=854 854w, /contentassets/cccca061546d43e9bedd877894559fab/tomas_gustafsson.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Tomas Gustafsson is infectious disease physician at Sunderby Hospital and researcher at the Department of Clinical Microbiology at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>Frida jakobsson</span></div></div><p class="quote-center">resistance is increasing against the current first line treatment ceftriaxone, which is very troublesome</p><p>&ldquo;Over the years, the bacteria that cause gonorrhoea has developed resistance to antibiotic after antibiotic and resistance is increasing against the current first line treatment ceftriaxone, which is very troublesome&rdquo;, says Tomas Gustafsson, infectious disease physician at Sunderby Hospital and researcher at the Department of Clinical Microbiology at Ume&aring; University.</p><p>Gonorrhoea is caused by the bacterium n<em>eisseria gonorrhoeae</em> (gonococci). It spreads through sexual contact, and it is the second most common sexually transmitted disease (STD). The incubation period is short &ndash; from a couple of days to a few weeks.&nbsp; &nbsp;</p><h2 id="info0" data-magellan-target="info0">No symptoms to infertility</h2><p>The most common symptoms of gonorrhoea are burning or discomfort when urinating and discharge from the urethra, vagina or rectum but can also give throat symptoms. However, many&mdash;especially women&mdash;may have no symptoms, which makes it easy to spread unknowingly.</p><p>&ldquo;The disease is quite contagious. The best way to avoid gonorrhoea is to use a condom which also gives protection against other STDs and HIV, but also to get tested if you have symptoms and participate in contact tracing&rdquo; says Tomas Gustafsson.</p><p>Gonorrhoea is rarely fatal, but if left untreated it can give rise to endometritis, pelvic inflammatory disease (PID), prostatitis and sometimes septic arthritis.</p><p>&ldquo;If gonorrhoea is not treated, it can even lead to infertility in women because the infection can cause lasting damage to the reproductive organs&rdquo;, says Tomas Gustafsson.</p><h2 id="info1" data-magellan-target="info1">Reduced treatment options&nbsp;</h2><p>Gonorrhoea has developed resistance to&nbsp;nearly all antibiotics&nbsp;historically used to treat it, and in recent years antibiotic resistance has increased rapidly.</p><p>Tomas Gustafsson splits his time between treating patients as an infectious disease physician and conducting research at Ume&aring; University. This dual role gives him a unique perspective on the growing challenge of antibiotic resistance.</p><p>&ldquo;I see the consequences of resistant infections firsthand in the clinic,&rdquo; he says. &ldquo;That experience is what pushed me to explore new treatment options in the lab.&rdquo;</p><p>While working with an antibiotic candidate which originally focused on other bacteria, he decided to test it against gonococci. Since then, the focus has mostly shifted towards development of methods to facilitate the drug-development process against gonococci, which are often much more challenging to work with than other bacteria.</p><p>&ldquo;We are trying to patch up some holes in the drug development pipeline to prevent it from running dry.&rdquo;</p><p><em><strong>What is the dream goal with your research?</strong></em></p><p>&ldquo;I guess I share it with most researchers involved in antibiotic development&hellip; to see an antibiotic candidate you have worked on, enter the clinic and be used to cure patients. That would be great!&rdquo;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/cccca061546d43e9bedd877894559fab/2017-04-13_n._gonorrhoeae_vs_aur_img_56052.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/cccca061546d43e9bedd877894559fab/2017-04-13_n._gonorrhoeae_vs_aur_img_56052.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/cccca061546d43e9bedd877894559fab/2017-04-13_n._gonorrhoeae_vs_aur_img_56052.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/cccca061546d43e9bedd877894559fab/2017-04-13_n._gonorrhoeae_vs_aur_img_56052.jpg?mode=crop&amp;width=640 640w, /contentassets/cccca061546d43e9bedd877894559fab/2017-04-13_n._gonorrhoeae_vs_aur_img_56052.jpg?mode=crop&amp;width=854 854w, /contentassets/cccca061546d43e9bedd877894559fab/2017-04-13_n._gonorrhoeae_vs_aur_img_56052.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Disc diffusion test with an investigational compounds with activity against gonococci.</p><span class="bildPhotografer"><span class="photo">Image</span>Tomas Gustafsson</span></div></div>/en/news/gonorrhoea-is-spreading-and-outsmarting-antibiotics_12131315//en/news/who-warns-of-chikungunya-virus-outbreak--5-questions-to-virus-researcher_12129990/This summer, the World Health Organization, WHO, has appealed to prevent a repeat of an epidemic of the chikungunya virus, that swept the world twenty years ago. Let us learn more by asking Lars-Anders Carlson, Associate Professor at Umeå University, five questions.Wed, 20 Aug 2025 08:10:01 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/fdd37b07281b4c3f8119c1cf517b2092/carlsson_lars-anders_8369-241022-mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/fdd37b07281b4c3f8119c1cf517b2092/carlsson_lars-anders_8369-241022-mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/fdd37b07281b4c3f8119c1cf517b2092/carlsson_lars-anders_8369-241022-mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/fdd37b07281b4c3f8119c1cf517b2092/carlsson_lars-anders_8369-241022-mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/fdd37b07281b4c3f8119c1cf517b2092/carlsson_lars-anders_8369-241022-mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/fdd37b07281b4c3f8119c1cf517b2092/carlsson_lars-anders_8369-241022-mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Lars-Anders Carlson's group at Ume&aring; University is doing research on the chikungunya virus.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">Luckily, the mosquitos we have in Sweden do not carry the virus</p><p>The cause for concern is new outbreaks reported in the Americas, Africa, Asia, and Europe (France and Italy). A major outbreak is underway in China, especially in the southern part. The most common symptoms of chikungunya virus infection are fever and muscle and joint pain. Chikungunya virus is spread to humans by infected mosquitoes and cannot be spread directly from person to person.</p><p>The infection is caused by a virus belonging to the alphavirus group. It creates &ldquo;factories&rdquo; on the cell surface where its genes are copied when the virus infects a cell. Lars-Anders Carlson's research group wants to understand how these viral factories work, to ultimately help in the efforts to design new antiviral strategies.</p><h2 id="info0" data-magellan-target="info0">Is the chikungunya virus very contagious and how does the virus spread?</h2><p>&ldquo;Yes, the virus is contagious, but only if you get bitten by an infected mosquito. Luckily, the mosquitos we have in Sweden do not carry the virus!&rdquo;</p><p>&ldquo;The viruses are spread through bites by mosquitos of the genus <em>Aedes</em>. Some twenty years ago, it seemed like Chikungunya virus was primarily spread by <em>Aedes aegypti</em>, a tropical mosquito. But in 2006, a massive outbreak took place on the island La R&eacute;union, and scientists could show that the virus, with a minimal mutation, had adapted itself to a new mosquito species, <em>Aedes albopictus</em>. This mosquito, which is known as the Asian tiger mosquito, is more widely spread, which allowed chikungunya virus to also spread more widely, for example to Southern Europe.&rdquo;</p><h2 id="info1" data-magellan-target="info1">Is the chikungunya fever dangerous?</h2><p>&ldquo;Most infections are probably mild, but this is hard to know exactly since many infections probably go undiagnosed. But infections can become more severe. The most devastating consequence is probably severe joint pain which can last for several months. There are also rare reports of chikungunya-caused encephalitis.&rdquo;</p><h2 id="info2" data-magellan-target="info2">Is there a cure or vaccine?</h2><p>&ldquo;As of very recently (2024) there is actually a vaccine, called Ixchiq. It is based on Swedish research from Karolinska Institutet. It is very exciting to see some progress on this. Unfortunately, there is now a temporary restriction on giving this vaccine to people older than 65 due to some side effects observed, so we will see how it develops.&rdquo;</p><h2 id="info3" data-magellan-target="info3">Should we be afraid that chikungunya virus reaches Sweden?</h2><p>&ldquo;That is not my expertise, but my understanding is that it probably will not come here any time soon. However, the <em>Aedes</em> mosquitos are slowly moving up from southern to middle Europe, and only this year I saw that they may expect chikungunya infections in southern Germany.&rdquo;</p><p>&ldquo;A related virus called Sindbis virus can sometimes be spread by Nordic mosquitos to cause what in Swedish is called &ldquo;<em>Ockelbosjukan</em>&rdquo;, which resembles a milder chikungunya fever. The Norwegians have a fun name for this &ndash; they call it <em>b&aelig;rplukkersyken</em>, the berry-pickers disease.&rdquo;</p><h2 id="info4" data-magellan-target="info4">Why are you doing research about this virus and what is the dream goal?</h2><p>&ldquo;I am interested in some very fundamental aspects of the virus factories that the virus creates to copy its genes. This machinery is fascinating to me! We are using electron microscopy to create detailed tree-dimensional images of the virus factories and use these images to gradually understand how the factories work. Eventually this might allow us to see how the virus copies its genes at the resolution of individual atoms. We are not quite there yet, so some work remains. Eventually, I think we can get a complete understanding of how they work!&rdquo;</p>/en/news/who-warns-of-chikungunya-virus-outbreak--5-questions-to-virus-researcher_12129990//en/news/alzheimers-like-disease-in-patients-with-parkinsons_12116038/One in ten patients diagnosed with Parkinson's disease may have another neurological disease that is more similar to Alzheimer's than Parkinson's. This is shown by a new Swedish study that is based on samples that have been taken from patients in Umeå, Sweden.Tue, 01 Jul 2025 10:37:15 +0200<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/75469515c45c4d7a8256e964c810d6ea/david_backstrom_120922_spn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/75469515c45c4d7a8256e964c810d6ea/david_backstrom_120922_spn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/75469515c45c4d7a8256e964c810d6ea/david_backstrom_120922_spn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/75469515c45c4d7a8256e964c810d6ea/david_backstrom_120922_spn2.jpg?mode=crop&amp;width=640 640w, /contentassets/75469515c45c4d7a8256e964c810d6ea/david_backstrom_120922_spn2.jpg?mode=crop&amp;width=854 854w, /contentassets/75469515c45c4d7a8256e964c810d6ea/david_backstrom_120922_spn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>David B&auml;ckstr&ouml;m, neurologist and researcher at Department of Clinical Sciences, Ume&aring; University<span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Samuel Petterson, Fri Tanke publishing house</span></p></div></div><p>"This is an important result that can change our understanding of the course of the disease and, in the long run, affect the treatment of some patients diagnosed with Parkinson's," says David B&auml;ckstr&ouml;m, neurologist, senior lecturer at Ume&aring; University and one of the study's lead authors.</p><p class="quote-left">can change our understanding</p><p>The researchers have performed a so-called &alpha;-synuclein seed amplification assay (&alpha;Syn-SAA) of cerebrospinal fluid in 140 patients at Norrland University Hospital who had been diagnosed with Parkinson's disease and similar diseases, as well as in 30 healthy people in a control group.</p><p>The protein &alpha;-synuclein is usually linked to Parkinson's disease. Surprisingly, the sampling showed that about ten percent of the Parkinson's patients examined lacked aggregation of this protein, which is otherwise considered a marker for Parkinson's.</p><p>When the researchers examined these &alpha;-synuclein-negative patients more closely, they found that they often had typical markers in the cerebrospinal fluid of Alzheimer's disease, such as amyloid and tau proteins. These patients also showed slightly poorer cognitive ability and balance than normal for Parkinson's patients.</p><p>It seems to be something of an intermediate form of Parkinson's and Alzheimer's that the researchers have now found. It has previously been clinically observed that some patients with Alzheimer's have also shown symptoms similar to Parkinson's. What is new that the researchers can now show is that the similarity is so great that many of these patients have instead been diagnosed with Parkinson's, and that these patients have a specific profile of biomarkers. This may affect how diagnosis and treatment are made in the future.</p><p>"One possible development is that these patients can be treated with drugs used for Alzheimer's. It is at least a track to research further and something that could be tested in drug studies," says David B&auml;ckstr&ouml;m.</p><p>The research has been carried out in collaboration between researchers in Ume&aring;, Gothenburg, Sweden, and San Diego in the United States. The study is published in the scientific journal Alzheimer's &amp; Dementia.</p>/en/news/alzheimers-like-disease-in-patients-with-parkinsons_12116038//en/news/doctors-struggle-with-empathy-in-a-high-pressure-work-environment_12103472/Empathy is often seen as a natural and essential part of the patient encounter – but reality tends to look quite different. In a new doctoral thesis from Umeå University, doctors describe how not only time pressure, but also the structure of medical education and the culture of the workplace, can make it difficult to live up to the ideal.Mon, 02 Jun 2025 09:00:04 +0200<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"></div><div class="bildText"><p>Johanna Von Knorring.</p><span class="bildPhotografer"><span class="photo">Image</span>Hans Karlsson</span></div></div><p>In her thesis, Johanna von Knorring interviewed medical students, practicing doctors, and patients about how they experience and understand empathy in healthcare. The results show that empathy is relational and constantly changing &ndash; and that it is influenced by far more than an individual doctor&rsquo;s will or personality.</p><p>Participants in the study describe empathy as difficult to define, yet a natural part of a good healthcare encounter. It involves being present, listening actively and meeting the patient as a whole person &ndash; not just as a diagnosis. For patients, an empathetic approach can help create safety, trust and greater involvement in their own care.</p><p class="quote-center">There is a clash between what you&rsquo;ve been taught to strive for and what you&rsquo;re actually able to do in your daily work.</p><p>Although empathy is considered an ideal, the study highlights how difficult it can be to achieve in everyday practice. Medical students say that empathy is given attention in the early stages of their education, but once they enter the clinical environment, they face a reality shaped by time constraints, documentation demands and a strong focus on technical and medical efficiency &ndash; all of which make it harder to remain empathetically present.</p><p>&ldquo;There is a clash between what you&rsquo;ve been taught to strive for and what you&rsquo;re actually able to do in your daily work,&rdquo; says Johanna von Knorring, doctoral student at the Department of Clinical Sciences and the Industrial Doctoral School at Ume&aring; University.</p><h2 id="info0" data-magellan-target="info0">Limited space for reflection</h2><p>Experienced doctors also describe how their empathy is negatively affected by the work environment, organisational conditions and a workplace culture that often prioritises efficiency over relational care. Many hope to serve as role models for younger colleagues &ndash; but find that there is limited space for reflection and discussion on patient interaction. At the same time, they emphasise that empathy does not disappear, but that it requires ongoing effort and support to be maintained.</p><p>Patients in the study show great understanding of the challenges faced by healthcare professionals but still call for a more person-centered approach &ndash; to be seen, heard and taken seriously. For them, empathy is not a bonus but a fundamental part of quality care.</p><h2 id="info1" data-magellan-target="info1">Shared responsibility</h2><p>In summary, the thesis shows that empathy does not simply emerge in the encounter between two individuals. It is shaped by the design of medical education, workplace cultures and the values embedded in the healthcare system.</p><p>&ldquo;We need to understand empathy as something shaped and reshaped by its context. Creating better conditions for doctors to maintain and develop their empathy is a shared responsibility &ndash; one that rests with individuals, educational institutions and healthcare organisations,&rdquo; says Johanna von Knorring.</p><p><em>Johanna von Knorring&rsquo;s doctoral project has been funded by the Industrial Doctoral School at Ume&aring; University and Region V&auml;sterbotten. She is also a specialist trainee in oncology and teaches at the medical programme.</em></p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="76ffbd5d-99cb-4b75-b578-63d94a7ce6c7" data-contentname="About the public defence">{}</div><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="74b92039-6a80-4930-ba4f-6ad48cdf6752" data-contentname="Fakta Företagsforskarskolan ENG (standard)">{}</div>/en/news/doctors-struggle-with-empathy-in-a-high-pressure-work-environment_12103472//en/news/vice-chancellor-blogs-on-the-universitys-role-in-conflicts_12103628/The Royal Swedish Academy of Sciences has decided to award the Florman Prize to Changchun Chen at Umeå University. The prize sum is 135,000 SEK.Tue, 27 May 2025 13:50:05 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/fd2e73ededa343cea0faed59e51690b6/changchun_chen_23.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/fd2e73ededa343cea0faed59e51690b6/changchun_chen_23.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/fd2e73ededa343cea0faed59e51690b6/changchun_chen_23.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/fd2e73ededa343cea0faed59e51690b6/changchun_chen_23.jpg?mode=crop&amp;width=640 640w, /contentassets/fd2e73ededa343cea0faed59e51690b6/changchun_chen_23.jpg?mode=crop&amp;width=854 854w, /contentassets/fd2e73ededa343cea0faed59e51690b6/changchun_chen_23.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Changchun Chen is associate professor at Department of molecular biology at Ume&aring; University</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p class="quote-center">For me it is a signal of encouragement to keep going</p><p>&ldquo;I feel great! It was totally a surprise since there are so many excellent young scientists at Ume&aring; University and in Sweden who are doing really great research", says Changchun Cheng, associate professor at the Department of molecular biology at Ume&aring; University. &ldquo;For me it is a signal of encouragement to keep going&rdquo;.</p><p>The jury&rsquo;s motivation is &ldquo;&hellip; for having elucidated neural processes that regulate physiological and behavioural adaptations for survival under extreme living conditions using the nematode <em>C. elegans</em> as a model&rdquo;.</p><p>Changchun Chen is a molecular biologist into basic research and has worked at Ume&aring; University since the beginning of 2018. Using <em>C. elegans</em> as the primary model, he and his group focus on uncovering novel and conserved mechanisms that drive behavioural and physiological responses to stress conditions. This includes hypoxia-induced eating disorders, the remarkable tolerance of certain animals to complete oxygen deprivation, and the neuronal and immune responses to bacterial pathogens.</p><p>&ldquo;The reason why I use <em>C. elegans</em> as model system in my experiments is that it is one of the simplest animals with a nervous system, yet it is genetically very powerful, with a rich set of tools available for research&rdquo;, says Changchun Chen.</p><p>Importantly, many genes and cellular processes are highly conserved between <em>C. elegans</em> and humans, which allows researchers to gain molecular insights that can often be translated to more complex systems. Some well-known examples are programmed cell death, RNAi, and microRNAs.</p><p>Before coming to Ume&aring; University, Changchun Chen studied preventive medicine at Shanghai Medical College, followed by a doctoral thesis in yeast genetics at Ume&aring; University under the supervision of Professor Anders Bystr&ouml;m, and completed by postdoctoral training at Cambridge UK, studying neural control of aggregation behaviour in <em>C. elegans</em>.</p><p>The prize ceremony will take place on 27 November in Stockholm.</p>/en/news/prestigious-award-to-umea-molecular-biologist_12102961//en/news/fernstroms-prize-to-schroder_12102276/The 2025 Eric K Fernström Prize for Young, Particularly Promising and Successful Researchers is awarded to Associate Professor Björn Schröder at the Department of Molecular Biology, Umeå University, for his significant scientific contributions in the research field of host-microbiome interactions.Thu, 03 Jul 2025 16:58:49 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/ccad9eb7c2b84795b8c8076f6bc895a2/schroder_bjorn_5343_190405_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ccad9eb7c2b84795b8c8076f6bc895a2/schroder_bjorn_5343_190405_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ccad9eb7c2b84795b8c8076f6bc895a2/schroder_bjorn_5343_190405_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ccad9eb7c2b84795b8c8076f6bc895a2/schroder_bjorn_5343_190405_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/ccad9eb7c2b84795b8c8076f6bc895a2/schroder_bjorn_5343_190405_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/ccad9eb7c2b84795b8c8076f6bc895a2/schroder_bjorn_5343_190405_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Bj&ouml;rn Schr&ouml;der, Department of Molecular Biology and The Laboratory for Molecular Infection Medicine Sweden. MIMS.&nbsp;<span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Mattias Pettersson</span></p></div></div><p>In its citation, the prize committee at the Faculty of Medicine writes:</p><p>"Bj&ouml;rn Schr&ouml;der's research in the field has focused in particular on the molecular mechanisms through which diet affects the gut via the microbiome. His research group has been able to convincingly show that Western diets disrupt the mucus barrier in the colon through specific microbial and diet-related factors, an influence that increases susceptibility to inflammation. Schr&ouml;der's work has provided important insights into how diet-related changes in the microbiome impair gut health at the molecular level, and how these changes affect gut barrier functions and immune function."</p><p>The Eric K. Fernstr&ouml;m Shipowner Prize for young, particularly promising and successful researchers is given each year to young researchers at each of the six medical faculties in Sweden. In Ume&aring;, the prize winner is appointed by a special committee at the Faculty of Medicine.</p><p>The prize is awarded at Ume&aring; University's annual ceremony in October. The prize money is SEK 100,000. The prize winner will also receive a special diploma at a ceremony in Lund.</p>/en/news/fernstroms-prize-to-schroder_12102276//en/news/maternal-health-and-cardiology-in-focus-for-new-honorary-doctors-of-medicine_12102356/A professor of gynaecology and obstetrics from Indonesia and a cardiologist from Scotland will be awarded honorary doctorates by the Faculty of Medicine at Umeå University, Sweden, in 2025.Wed, 28 May 2025 10:24:03 +0200<div class="mediaflowwrapper bildlink halfwidthsquareleft"><div class="bildImage"><picture><source srcset="/contentassets/fc211c4284c34b059d4728290f99407e/mohammad_hakimi3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/fc211c4284c34b059d4728290f99407e/mohammad_hakimi3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/fc211c4284c34b059d4728290f99407e/mohammad_hakimi3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/fc211c4284c34b059d4728290f99407e/mohammad_hakimi3.jpg?mode=crop&amp;width=640 640w, /contentassets/fc211c4284c34b059d4728290f99407e/mohammad_hakimi3.jpg?mode=crop&amp;width=854 854w, /contentassets/fc211c4284c34b059d4728290f99407e/mohammad_hakimi3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Mohammad Hakimi, medical honorary doctor 2025.<span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Wisaksono Adhi, InaHealth, FK-KMK UGM</span></p></div></div><p>Mohammad Hakimi is a professor of Obstetrics and Gynaecology at Universitas Gadjah Mada, Indonesia. His work spans a wide range of areas with a focus on maternal and child health, nutrition, and public health equity. He has increased the understanding of obstetric care, micronutrient deficiencies, non-communicable diseases, and the health consequences of domestic violence. His academic output includes over 300 publications, alongside educational materials and books that have informed public health policy and practice.</p><p>For over three decades, Professor Hakimi has been a central figure in the longstanding collaboration between Universitas Gadjah Mada and the research and education in epidemiology and global health at Ume&aring; University. He has served as a guest researcher and mentor in Ume&aring;, and many of his former students now hold professorships in both Indonesia and Sweden, strengthening bilateral academic ties. This collaboration has resulted in more than 150 joint publications and 15 completed PhD projects.</p><p>"Mohammad Hakimi is a highly respected person in maternal and public health. His research and collaboration with Ume&aring; University has really made a difference both in Southeast Asia and for us," says Patrik Danielson, Dean of the Faculty of Medicine at Ume&aring; University.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/fc211c4284c34b059d4728290f99407e/bhf_-_prof_nick_mills_20252.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/fc211c4284c34b059d4728290f99407e/bhf_-_prof_nick_mills_20252.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/fc211c4284c34b059d4728290f99407e/bhf_-_prof_nick_mills_20252.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/fc211c4284c34b059d4728290f99407e/bhf_-_prof_nick_mills_20252.jpg?mode=crop&amp;width=640 640w, /contentassets/fc211c4284c34b059d4728290f99407e/bhf_-_prof_nick_mills_20252.jpg?mode=crop&amp;width=854 854w, /contentassets/fc211c4284c34b059d4728290f99407e/bhf_-_prof_nick_mills_20252.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Nicholas Mills, honorary doctor 2025.&nbsp;<span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Stewart Attwood</span></p></div></div><p>Nicholas Mills is an internationally renowned and well-qualified professor of cardiology at the University of Edinburgh, Scotland with approximately 450 publications of his own. During his time as a doctoral student, he spent several occasions in Ume&aring;, where he introduced venous occlusion plethysmography to study the cardiovascular effects of acute exposure to various air pollutants, primarily diesel exhaust.</p><p>Professor Mills has contributed to a well-functioning exchange of doctoral students between Ume&aring; and Edinburgh. He has acted as a mentor for researchers and doctoral students in Ume&aring;, which has resulted in five doctoral dissertations and about thirty scientific articles in prestigious journals. In addition, three doctoral students from Edinburgh have completed parts of their doctoral studies in Ume&aring;.</p><p>"Nick Mills' research methodology has been of great importance for studies of the importance of air pollution for cardiovascular disease, research that has become increasingly relevant and where Ume&aring; is now well advanced. It feels very good that we can now tie him more closely to us,&rdquo; says Patrik Danielson.</p><p>The honorary doctors will be conferred at Ume&aring; University's annual ceremony in October.</p>/en/news/maternal-health-and-cardiology-in-focus-for-new-honorary-doctors-of-medicine_12102356//en/news/a-blend-of-science-fun-and-nature-scenery-when-postdocs-meet_12100359/In mid-May, the postdoctoral fellows in the ’Excellence by Choice’ programme at Umeå university gathered for a lunch-to-lunch retreat in Kronlund in Vindeln. The scope of the meeting was to get to know each other, get new insights, and share experiences as an interdisciplinary postdoctoral fellow.Thu, 18 Sep 2025 09:20:01 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/postdoc_retreat.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/postdoc_retreat.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/postdoc_retreat.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/postdoc_retreat.jpg?mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/postdoc_retreat.jpg?mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/postdoc_retreat.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>In the front: Gabriel Torrens Ribot, Fredrik Almqvist, Joram Kiriga Waititu, and Suvam Roy. In the back: Samuel Agyei Nyantakyi, T&uacute;lio Yoshinaga, Antonio Blasquez, Jagadish Mangu, Harshit Malhotra, Dhruv Agrawal, Baptiste Bogard, Ben Johns, and Marta Bally.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p class="quote-center">It was inspiring to see how different areas of expertise can complement each other</p><p>&ldquo;The highlight of the retreat was realizing just how diverse and dynamic the research within our community truly is," says Joram Kiriga Waititu, postdoc in Kemal Avican, Johan Henriksson and Maria F&auml;llman labs at the Department of Molecular Biology at Ume&aring; University.</p><p>He continues:</p><p>"It was inspiring to see how different areas of expertise can complement each other, and it reinforced the idea that meaningful collaboration has the potential to drive real science breakthroughs.&rdquo;&nbsp;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/img_0381.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/img_0381.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/img_0381.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/img_0381.jpg?mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/img_0381.jpg?mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/img_0381.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Kronlund kursg&aring;rd is a nature lodge that specialises in offering a quiet, beautiful and relaxing atmosphere.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p>It was an enthusiastic group of eleven postdoctoral fellows who arrived in a minibus at Kronlund kursg&aring;rd.</p><p>&ldquo;The venue was super nice! I like peaceful places in the middle of nature like Kronlund. I hope to get back here another time&rdquo;, says T&uacute;lio Yoshinaga, postdoc in Constantin Urban lab at the Department of Clinical Microbiology at Ume&aring; University, Lo Persson&rsquo;s group at the Swedish University of Agricultural Sciences, and Henrik Jeute at the Ume&aring; County administrative board.</p><p>The uniqueness with the &lsquo;Excellence by Choice' postdoctoral programme in life science is that it aims to cross traditional discipline boundaries. Thus, each postdoc has created and lead a collaborative project under the supervision of at least two principal investigators with different areas of expertise.</p><p>The first &lsquo;EC&rsquo; postdoc started in 2022, and the number has summed up to 15 after four international calls. Some postdocs are in the initial stages and some are ready to take the next step in the career, all with different experiences and subjects.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/konferens_2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/konferens_2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/konferens_2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/konferens_2.jpg?mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/konferens_2.jpg?mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/konferens_2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Harshit Malhotra is one of the newest postdoc on board and he explained his research to come.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p>At the retreat everyone presented their project and how they have evolved. The subjects showed a fantastic variety in the field of life science: chemo-optogenetic tools to control cellular processes in bacteria, search for potential drug against the parasite <em>Cryptospodirium</em>, new method to prevent fungi disease in salmonids, the role of protein complexes in regulation of growth and development in plants, the regulation of the host cell epitranscriptome in salmonella infection &ndash; to mention a few.</p><p>For sure, a few postdocs could discover potential areas for new collaboration.</p><p>Through games and other activities, the postdocs spend some relaxing time in the afternoon and evening with valuable conversations about life in general and of course about research.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/game_2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/game_2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/game_2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/game_2.jpg?mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/game_2.jpg?mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/game_2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>An exciting pentathlon took place in the afternoon with a lot of laughter.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div><p>In a final session before going home the next day, UCMR directors Fredrik Almqvist and Marta Bally led a group discussion on future career steps. What opportunities are there after a postdoc? What are my needs in career support? Ho can I navigate to pursue my career in academia or industry?</p><p>It might be important to position yourself for a competitive academic or professional future. The postdocs found this session urgent and were engaged.</p><p>&ldquo;I learned that I should focus on becoming more independent already after my first postdoc position, says Suvam Roy, postdoc in Eric Libby lab at the Department of Mathematics and Mathematical Statistics, and Peter Lind lab at the Department of Molecular Biology at Ume&aring; University.</p><p>&ldquo;This topic is very important for us, and it could have had an even more prominent place in the schedule to ensure everyone has the time and space to share experiences, ask questions, and explore different career paths more deeply,&rdquo; says Joram Kiriga Waititu.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/grill_12.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/grill_12.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/grill_12.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/0c8e91438d7447c184166dd34c02c6c1/grill_12.jpg?mode=crop&amp;width=640 640w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/grill_12.jpg?mode=crop&amp;width=854 854w, /contentassets/0c8e91438d7447c184166dd34c02c6c1/grill_12.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Perhaps it is right there at the edge of the forest by the Vindel River, with a cup of coffee in hand and a new colleague by your side, that the next major scientific breakthrough begins to take shape.</p><span class="bildPhotografer"><span class="photo">Image</span>Ingrid S&ouml;derbergh</span></div></div>/en/news/a-blend-of-science-fun-and-nature-scenery-when-postdocs-meet_12100359//en/news/dna-patterns-provide-key-insights-in-the-diagnosis-of-childhood-leukemia_12080856/The University Board has, on the recommendation of Vice-Chancellor Tora Holmberg, appointed Patrik Danielson as the new Pro-Vice-Chancellor and Vice-Chancellor's deputy for the period 1 July 2025 – 30 June 2031. "Patrik has a solid and long experience as a manager and leader at the university. He has also worked successfully on collaboration, which is crucial for conducting research and education of good quality," says Tora Holmberg.Sat, 24 May 2025 12:06:03 +0200<p>The work of producing proposals for the Pro-Vice-Chancellor has been a thorough process. Tora Holmberg took the opportunity to enlist the help of the same recruitment committee that the University Board put together for the recruitment of a new Vice-Chancellor. In this way, the process and the dialogue already established between the Consultative Assembly and the Recruitment Committee could ensure good management.</p><p>The Consultative Assembly, led by Chair Richard Bindler, met Patrik Danielson on 12 March to ask questions and unanimously decided to support the proposal for a new Pro-Vice-Chancellor.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/303e206266c9425c8485934eade164e8/danielson_patrik_05062024_hkn-3_32.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/303e206266c9425c8485934eade164e8/danielson_patrik_05062024_hkn-3_32.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/303e206266c9425c8485934eade164e8/danielson_patrik_05062024_hkn-3_32.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/303e206266c9425c8485934eade164e8/danielson_patrik_05062024_hkn-3_32.jpg?mode=crop&amp;width=640 640w, /contentassets/303e206266c9425c8485934eade164e8/danielson_patrik_05062024_hkn-3_32.jpg?mode=crop&amp;width=854 854w, /contentassets/303e206266c9425c8485934eade164e8/danielson_patrik_05062024_hkn-3_32.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Patrik Danielsson, Pro-Vice-Chancellor, Ume&aring; University</p><span class="bildPhotografer"><span class="photo">Image</span>Hans Karlsson</span></div></div><p>Patrik Danielson is Professor of Anatomy, Senior Consultant in Ophthalmology and since 2017 Dean of the Faculty of Medicine at Ume&aring; University.</p><p>"Patrik's disciplinary background also complements my role in a good way. I am very pleased with this recruitment and look forward to a good collaboration that will provide the best conditions for Ume&aring; University," says Tora Holmberg.</p>/en/news/patrik-danielson-appointed-new-pro-vice-chancellor-at-umea-university_12099772//en/news/diabetesmedicin-ger-hopp-om-ny-behandling-mot-prostatacancer_12097228/A drug used to treat type 2 diabetes may also be effective in slowing the progression of prostate cancer. This is shown by an international study in which researchers at Umeå University, Sweden, have participated. The researchers have found that drugs that regulate a particular protein have a key role in reducing prostate cancer recurrence among diabetic patients.Thu, 22 May 2025 11:00:20 +0200<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/c07ae8d4ff37449fb4b39748de18c3bf/lukas_kenner2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c07ae8d4ff37449fb4b39748de18c3bf/lukas_kenner2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c07ae8d4ff37449fb4b39748de18c3bf/lukas_kenner2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c07ae8d4ff37449fb4b39748de18c3bf/lukas_kenner2.jpg?mode=crop&amp;width=640 640w, /contentassets/c07ae8d4ff37449fb4b39748de18c3bf/lukas_kenner2.jpg?mode=crop&amp;width=854 854w, /contentassets/c07ae8d4ff37449fb4b39748de18c3bf/lukas_kenner2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Lukas Kenner, visiting professor at Department of Molecular Biology, Ume&aring; University.<span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Medizinische Universit&auml;t Wien</span></p></div></div><p>"This is a significant discovery. For the first time, we have clinical observations showing that prostate cancer patients with diabetes who received drugs targeting the protein remained relapse-free during the period we followed them," says Lukas Kenner, visiting professor at Ume&aring; University and one of the study's lead authors.</p><p class="quote-left">a significant discovery</p><p>The protein that the researchers have studied is called PPARy, peroxisome proliferator-activated receptor gamma. In diabetes research, PPARy has been extensively studied in view of the protein's role in metabolic processes and insulin sensitivity.</p><p>What the research team, led by Professor Kenner, has now shown is that patients who were treated for prostate cancer and who also had diabetes, who were treated with drugs that regulate the PPARy protein, managed without recurrence of prostate cancer. In studies of cell cultures, researchers also observed that the drug in question, pioglitazone, not only inhibits the growth of prostate cancer cells but also drives a metabolic reprogramming of the cancer cells, weakening their ability to grow.</p><p>"The findings are very promising, but further clinical studies are needed to both confirm the results and to investigate whether the treatment can also be used in patients with prostate cancer who do not have diabetes," says Lukas Kenner.</p><p>The research has been conducted as a combination of studies on cells and mice as well as a retrospective study of 69 prostate cancer patients with type 2 diabetes that was followed by the Medical University of Innsbruck in 2014&ndash;2023.</p><p>In certain types of cancer, PPAR&gamma; can contribute to tumour growth or metabolic changes. The drug, pioglitazone, is a so-called agonist that binds to a PPARy receptor and activates it. Thereby it modulates the signalling pathway and aims to counteract tumour-promoting effects by changing the cellular metabolism but may also reduce inflammation.</p><p>The research group behind the study includes researchers in Austria, the Czech Republic, Germany, the United Kingdom, and Sweden. The study is published in the scientific journal Molecular Cancer.</p><p>Prostate cancer is the most common cancer-related cause of death among men in Sweden, with over 2,000 deaths per year, almost 400&nbsp;000 deaths worldwide. Prostate cancer is usually treated with hormone therapy, radiation, or surgery. However, the risk of relapse is relatively high.</p>/en/news/diabetesmedicin-ger-hopp-om-ny-behandling-mot-prostatacancer_12097228//en/news/new-discovery-explains-why-men-more-are-more-affected-from-severe-covid-19_12094879/Researchers at Umeå University have found another piece of the puzzle that explains why there are differences in immune responses in women and men when they get sick with COVID-19. This discovery has implications for treatment strategies for severe COVID-19. The study is published in the scientific journal European Journal of Immunology.Tue, 20 May 2025 14:18:38 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7173-250509-mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7173-250509-mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7173-250509-mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7173-250509-mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7173-250509-mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7173-250509-mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Johan Normark och Constantin Urban, Institutionen f&ouml;r klinisk mikrobiologi vid Ume&aring; universitet.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">men are three times more likely to need intensive care</p><p>&ldquo;Although the total number of cases of diagnosed COVID-19 is similar for men and women, men are three times more likely to need intensive care. Our study contributes to understanding how this sex-related difference in severe COVID-19 arises&rdquo;, says Johan Normark, infectious disease physician and senior lecturer at the Department of Clinical Microbiology at Ume&aring; University and one of the researchers behind the studies.</p><h2 id="info0" data-magellan-target="info0">Non-existent to severe symptoms</h2><p>COVID-19 is a respiratory infection caused by the SARS-CoV-2 virus. The disease was first detected during the coronavirus outbreak in Wuhan, China, in December 2019. The rapid, global spread led to the COVID-19 pandemic.</p><p>At least a third of those infected do not experience any symptoms. Of those who do, 80 percent experience mild symptoms and 20 percent experience severe symptoms that may require hospitalization and oxygen support. A small proportion of these becomes critically ill and requires intensive care.</p><p>Severe COVID-19 infections are characterized by an exaggerated and hyperinflammatory reaction of the immune system, especially in the lungs. The severe response can lead to tissue damage and, in the worst case, death. Part of the immune response to COVID-19 is the recruitment and activation of special white blood cells, called neutrophils. Their recruitment and activation occur primarily through the secretion of immune system signaling molecules, called cytokines.</p><p>The underlying mechanisms of why men are at risk of becoming more seriously ill with COVID-19 are not fully known.</p><h2 id="info1" data-magellan-target="info1">Physicians and researchers collaborate</h2><p>To explore this, a translational project led by Professor Constantin Urban was started, where several research groups from Ume&aring; University collaborated with partners at the university hospitals in Ume&aring; and &Ouml;rebro. Translational research aims to take what is learned in basic research and apply it to the development of solutions to medical problems.</p><p>In the study, blood samples from over 200 Swedish patients with COVID-19 were analyzed. Using the samples, doctoral student Remigius Gr&ouml;ning mapped a comprehensive cytokine profile and doctoral student Emelie Backman quantified molecules that indicate neutrophil activation.</p><h2 id="info2" data-magellan-target="info2">Excessive activation of the immune system in men</h2><p>The results showed that in the samples from patients with severe COVID-19 and needing medical care, there were higher values ​​of cytokines that recruit and activate neutrophils. In addition, there were higher values ​​of neutrophil activation markers.</p><p>&ldquo;We saw that the increase in the inflammatory cytokine IL-18 was sex-dependent and that the activation of neutrophils was sex-dependent. This was our most interesting finding! On average, both the amount of this cytokine and neutrophil activation markers were higher in blood plasma from men with severe COVID-19 compared to blood plasma from women of the same category&rdquo;, says Constantin Urban. Excessive recruitment and activation of neutrophils can have fatal consequences and can lead to serious and life-threatening disease.</p><p>According to the researchers, the result is important because other studies are underway that aim to treat symptoms of severe COVID-19 by suppressing neutrophil activation and thus reducing tissue damage in the patients' lungs.</p><p>&ldquo;In order to further develop this treatment strategy, it is therefore tremendously important to precisely map the difference that occurs in neutrophil responses in men and women with severe COVID-19&rdquo;, says Constantin Urban.</p><h2 id="info3" data-magellan-target="info3">The immune system against viruses is complex</h2><p>The study also highlights the complexity of the interactions that characterize the immune system's response to viral infections and how these interactions can affect the severity of the disease. Neutrophils have previously been studied most in bacterial infections, but this study shows that they also play an important role in more severe viral infections.</p><p>In future studies, the research team intends to further delineate the molecular mechanisms behind the discovered sex-related differences in the COVID-19 response and to verify the results of the current study with larger patient groups.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7231-250509-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7231-250509-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7231-250509-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7231-250509-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7231-250509-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/667ad23d8cc2487dbb15c8f190f96dc2/johan-o-constantine-ucmr-7231-250509-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>The researchers Johan Normark and Constantin Urban plan to verify the results of the current study with larger patient groups.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div>/en/news/new-discovery-explains-why-men-more-are-more-affected-from-severe-covid-19_12094879//en/news/everyone-is-coughing-right-now_12092195/There is a lot of coughing at the moment and many people think that more people than usual are at home with cold symptoms, but is that really the case and if so, why? Niklas Arnberg is a Professor at Department of Clinical Microbiology at Umeå University and he is trying to answer the questions that are circulating in many workplaces and schools around Sweden right now.Mon, 19 May 2025 08:12:16 +0200<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/94a7089ab30f47f1b5e04f8d43fb4950/arnberg_niklas_6157_190815_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/94a7089ab30f47f1b5e04f8d43fb4950/arnberg_niklas_6157_190815_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/94a7089ab30f47f1b5e04f8d43fb4950/arnberg_niklas_6157_190815_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/94a7089ab30f47f1b5e04f8d43fb4950/arnberg_niklas_6157_190815_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/94a7089ab30f47f1b5e04f8d43fb4950/arnberg_niklas_6157_190815_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/94a7089ab30f47f1b5e04f8d43fb4950/arnberg_niklas_6157_190815_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Niklas Arnberg is a Professor at Department of Clinical Microbiology at Ume&aring; University. Photo: Mattias Pettersson.</p></div></div><h3>Right now, many people seem to have a cold and cough, is that the case and if so, what is actually circulating?</h3><p>"It's a combination of several different viruses. We're seeing a lot of the classic cold viruses, like rhinoviruses and enteroviruses, which usually cause runny noses, but also coughs and even pneumonia. But we also see influenza, parainfluenza viruses, common coronaviruses, although not so much COVID-19, as well as some RSV and metapneumoviruses. In other words, there are a lot of viruses contributing to more people coughing and sniffling than we usually see at this time of year."</p><h3>Is it unusual to have so many different viruses circulating at the same time?</h3><p>"Yes, it's actually a bit surprising that there are so many different viruses so late in the year. Usually, by this time, several of them have decreased significantly. One possible explanation is that we are still feeling some pandemic effect. The restrictions during the pandemic affected our exposure to viruses, which in turn has affected the immunity of the population. This has affected the epidemiological patterns and we don't seem to be back in balance yet. Every year is different, but since the pandemic we have seen an unusual amount of disruption in these patterns."</p><h3>Can we do anything to avoid all viruses?</h3><p>"Vulnerable groups in the population should be vaccinated according to the recommendations, but others can also be vaccinated against certain pathogens. Otherwise, the classic advice is to avoid large crowds, wash your hands often and those who are susceptible to infection can also use a face mask."</p><h3>Are we seeing an end to the viruses now?</h3><p>"It should calm down soon, we normally have less virus activity in summer, on the other hand we haven't had a clear peak of COVID-19 this winter, so there could be more during the summer. But most likely the worst should be over soon as it gets warmer and we spend more time outside."</p><p>&nbsp;</p>/en/news/everyone-is-coughing-right-now_12092195//en/news/discovery-opens-up-for-new-ways-to-treat-chlamydia_12091019/Researchers at Umeå University, Sweden, and Michigan State University, USA, have discovered a type of molecule that can kill chlamydia bacteria but spare bacteria that are important for health. The discovery opens the door for further research towards developing new antibiotics against chlamydia, the world's most common bacterial sexually transmitted disease with 130 million cases a year.Thu, 08 May 2025 07:30:56 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/769b6dde828f44409c7ec2b909c26361/barbara-magnus-aakriti-6164-250416-mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/769b6dde828f44409c7ec2b909c26361/barbara-magnus-aakriti-6164-250416-mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/769b6dde828f44409c7ec2b909c26361/barbara-magnus-aakriti-6164-250416-mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/769b6dde828f44409c7ec2b909c26361/barbara-magnus-aakriti-6164-250416-mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/769b6dde828f44409c7ec2b909c26361/barbara-magnus-aakriti-6164-250416-mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/769b6dde828f44409c7ec2b909c26361/barbara-magnus-aakriti-6164-250416-mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Magnus &Ouml;lander, postdoc in the Sixtlab, sharing exciting findings from an antibiotic discovery project with labhead Barbara Sixt and colleague Aakriti Singh. <br><span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Mattias Pettersson</span></p></div></div><p>"No one should have to live with chlamydia. But the problem is that the treatments we have today do not distinguish between dangerous and friendly bacteria. A growing problem is also that more and more bacteria are becoming resistant to today's broad-acting antibiotics," says the study's lead author Barbara Sixt, associate professor at the Department of Molecular Biology at Ume&aring; University, Sweden.</p><p>The bacterium that causes chlamydia, <em>Chlamydia trachomatis</em>, has very special properties. Just like viruses, it invades cells in the human body, which it then reshapes so that they give the bacterium a home where it can grow and multiply.</p><p>"We thought it could be possible to find a way to outsmart the bacterium's lifestyle by interfering with its special properties and its interactions with human cells," says the study's first author Magnus &Ouml;lander, former postdoc at Ume&aring; University.</p><p>The researchers searched through large collections of chemical molecules to find molecules that can eradicate the growth of the chlamydia bacterium in human cells in laboratory cultures. More than 60 possible anti-chlamydia molecules were identified. It was a matter of finding molecules that could selectively kill the chlamydia bacterium but at the same time be harmless to human cells and to beneficial bacteria that the body needs to stay healthy. After further refined studies, the researchers were able to identify a particularly potent molecule.</p><p>The molecule in question was found to be able to inhibit the bacterium's ability to produce fatty acids, which are necessary for its growth.</p><p>"There is still a long way to go before we have a new treatment, but this finding may prove very important in developing new antibiotics that are both effective but at the same time gentle on the body&rdquo;, says Barbara Sixt.</p><p>The research was carried out in collaboration with Andr&eacute; Mateus and Bj&ouml;rn Schr&ouml;der at Ume&aring; University, Sweden, and Jeremy Lohman at Michigan State University, United States of America.</p><p>Chlamydia often causes mild symptoms but if left untreated can cause long-term damage to the reproductive organs, especially in women. This can cause chronic pain and infertility and can have consequences for pregnancy and childbirth. Chlamydia may also contribute to the onset of cancer of the cervix and ovaries. Every year, about 25,000 people in Sweden are diagnosed with chlamydia, 130 million worldwide.</p><p>The study is published in the scientific journal PLoS Biology.</p>/en/news/discovery-opens-up-for-new-ways-to-treat-chlamydia_12091019//en/news/umea-university-ready-for-european-collaboration_12090356/Ceremony for excellent and merited teachers, ceremony for new doctors and jubilee doctors, banquet and installation of the new Vice-Chancellor Tora Holmberg. It’s time for Spring Graduation at Umeå University. Wed, 30 Apr 2025 11:24:40 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/varpromotionen-gruppbild_2024_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/varpromotionen-gruppbild_2024_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/varpromotionen-gruppbild_2024_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/varpromotionen-gruppbild_2024_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/varpromotionen-gruppbild_2024_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/varpromotionen-gruppbild_2024_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Picture from last years Spring Graduation ceremony.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>On Thursday 15 May, the ceremony for the University's excellent and merited teachers will take place. It is an occasion to celebrate and recognise those who have been appointed from autumn 2023 to autumn 2024, a total of 34 teachers will participate. During the ceremony, each teacher will be presented with a pin and thanked by representatives of the university management, students and the teaching staff.&nbsp; &nbsp;</p><p>&ldquo;Teachers are one of the cornerstones of the university's activities. Therefore, it feels good to recognise them on one of the university's most festive occasions. We hope for a good turnout,&rdquo; says Cathrine Norberg, Deputy Vice-Chancellor for education on the first- and second-cycle level at Ume&aring; University, and the person representing Ume&aring; University at the ceremony. &nbsp;</p><p>The ceremony for excellent and merited teachers will be held in Ljusg&aring;rden on Campus Ume&aring; 12.30&ndash;13.15. All interested parties are welcome.&nbsp;</p><h2 id="info0" data-magellan-target="info0">Recognising researchers</h2><p>On Saturday 17 May, it is time for the Spring Graduation ceremony in Aula Nordica in Universum on Campus Ume&aring;. Researchers at Ume&aring; University will be honoured. During this year's ceremony, 86 new doctors and 18 jubilee doctors will be conferred, 7 of the jubilee doctors will be present, the rest will be conferred absent. Jubilee doctors are people who received their doctorate 50 years ago.&nbsp; &nbsp;</p><p>During the ceremony, the doctoral insignia are handed out &ndash; the doctoral hat or laurel wreath, doctoral ring and diploma.&nbsp; &nbsp;</p><p>&ldquo;We are so proud of the breadth of socially important and innovative research conducted at Ume&aring; University. This is really something to recognise and celebrate,&rdquo; says Peter Sk&ouml;ld, Master of Ceremonies at Ume&aring; University.&nbsp; &nbsp;</p><h2 id="info1" data-magellan-target="info1">New Vice-chancellor is installed</h2><p>The academic ceremonies are very traditional. However, one tradition that doesn't happen every year is the installation of a Vice-chancellor &ndash; but this year it's time. On 1 April, Tora Holmberg started her position as Vice-chancellor at Ume&aring; University. During the Spring Graduation, the former Vice-chancellor, Hans Adolfsson, will place the gold Vice-chancellor chain around her neck. The chain is a sign of the dignity of the office. &nbsp;</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/holmberg-tora-5543-250403-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/holmberg-tora-5543-250403-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/holmberg-tora-5543-250403-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/holmberg-tora-5543-250403-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/holmberg-tora-5543-250403-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/77f6e502362f4c5bac60b6b73b9bcdc3/holmberg-tora-5543-250403-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Tora Holmberg is new Vice-chancellor since 1 April.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">It feels great to be able to wear the mighty Vice-chancellor chain and be part of one of the university's most important ceremonies.</p><p>Tora Holmberg becomes the ninth Vice-chancellor to be installed in the university's 60-year history.&nbsp; &nbsp;</p><p>&ldquo;It feels great to be able to wear the mighty Vice-chancellor chain and be part of one of the university's most important ceremonies. I have only had a short time to get to know Ume&aring; University. This ceremonial act will be an important step in my role as Vice-chancellor,&rsquo; says Tora Holmberg.&nbsp;</p><p>The ceremony will take place in Aula Nordica in Universum at Ume&aring; University on Saturday 17 May at 16.00. The entire ceremony is open to the public, and will last 1.5-2 hours. It is possible to watch a live webcast of the ceremony. A banquet for invited guests will follow.&nbsp;</p><p><a title="live.ͯ����Ƶ" href="/live">Watch the live broadcast at ͯ����Ƶ/live.&nbsp;</a></p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="f7aeaf74-affc-4407-8cf3-a5613c2a1464" data-contentname="Facts abour vice-chancellor chain">{}</div>/en/news/vice-chancellor-tora-holmberg-is-installed-at-the-spring-graduation_12087725//en/news/new-cells-in-connective-tissue-open-up-strategy-against-pancreatic-cancer_12081322/Researchers at Umeå University, Sweden, have discovered a previously unknown type of connective tissue cells that surround cancer cells in pancreatic tumors. The newly discovered cells counteract tumor development and may therefore be a target for research into new treatments for pancreatic cancer, which is one of the deadliest forms of cancer.Wed, 23 Apr 2025 09:21:12 +0200<p>We are still a long way from treatment, but this may show a viable path for further research," says Daniel &Ouml;hlund, associate professor at Ume&aring; University and who has ledleader of the current study.</p><p>Pancreatic cancer is one of the cancers with the worst prognosis for survival. This is partly because it is often detected late, and partly because it responds poorly to traditional treatments with chemotherapy.</p><p>Researchers at Ume&aring; University have investigated the connective tissue cells that surround the cancer cells in pancreatic cancer. These cells, called cancer-associated fibroblasts (CAF,), play an important role in how the cancer develops. Several types of CAF stimulate the growth of cancer cells and contribute to the cancer cells being resistant to current chemotherapy treatments. They thus make, making the cancer more aggressive and more difficult to treat.</p><p>What the Ume&aring; researchers have found is a previously unknown subgroup of CAF that has opposite properties. This group can instead hold back the cancer and open the way for the body's own immune cells to attack the cancer cells. However, this newly discovered group, called ifCAF &ndash; interferon response cancer-associated fibroblasts, (ifCAF), is in the minority among different CAF around the cancer cells.</p><p>"The opening we see is whether it would be possible to stimulate the formation of this newly discovered and kinder cell type around the cancer cells at the expense of the connective tissue cells that make the cancer aggressive," says Daniel &Ouml;hlund.</p><p>The researchers at Ume&aring; University are now proceeding to study potential drug substances that can promote the formation of ifCAF cells so that they increase in number and thus slow down the development of the disease. If successful, it could become a target for the development of future drugs. <br>About half a million people worldwide are diagnosed with pancreatic cancer every year<br>The study is published in the scientific journal Cancer Research.</p><p>About half a million people worldwide are diagnosed with pancreatic cancer every year.</p><p>The study is published in the scientific journal Cancer Research.</p>/en/news/new-cells-in-connective-tissue-open-up-strategy-against-pancreatic-cancer_12081322//en/news/ny-sidadiscovery-of-bacterias-defence-against-viruses-becomes-a-piece-of-the-puzzle-against-resistance_12074262/Antibiotic resistance is a global health challenge that could overtake cancer mortality within a few decades. In a new study, researchers at Umeå University show that the emergence of resistance can be understood in the mechanism of how bacteria build up defences against being infected by viruses. It is about genes in the bacterium that interfere with the attacking virus's ability to multiply. Thu, 10 Apr 2025 13:59:23 +0200<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/8a6ef1107f724148a32ea01eefcdcbf5/mir-sanchis_ignacio_3778_190320_mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/8a6ef1107f724148a32ea01eefcdcbf5/mir-sanchis_ignacio_3778_190320_mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/8a6ef1107f724148a32ea01eefcdcbf5/mir-sanchis_ignacio_3778_190320_mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/8a6ef1107f724148a32ea01eefcdcbf5/mir-sanchis_ignacio_3778_190320_mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/8a6ef1107f724148a32ea01eefcdcbf5/mir-sanchis_ignacio_3778_190320_mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/8a6ef1107f724148a32ea01eefcdcbf5/mir-sanchis_ignacio_3778_190320_mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ignacio Mir-Sanchis, Assistant Professor and lead author of the study. <br><span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Mattias Pettersson</span></p></div></div><p>"A key to antibiotic resistance might be the use of viruses to kill bacteria, however, the systems that bacteria employ to defence themselves against viruses are unknown. Understanding these systems opens up for research into how we can break down the defence so that serious infection disease can be treated in the future," says Ignacio Mir-Sanchis, Assistant Professor at Ume&aring; University and the study's lead author.</p><p>The Ume&aring; researchers have studied the bacterium Staphylococcus aureus, which is a common but potentially fatal bacterium in cases such as septic shock and pneumonia. A subgroup of S. aureus has become multi-resistant to antibiotic treatment and thus poses a major danger to public health. In some countries, a quarter of S. aureus is now multi-resistant, in Sweden only one percent.</p><p>However, the bacteria themselves are vulnerable to infection by a type of virus called bacteriophages, or just phages. Throughout evolution, bacteria and phages have undergone an arms race in which phages infect bacteria, which in turn develop mechanisms to resist the attacks. Much of this defence is encoded in the part of the bacteria's genome that can easily be transferred between bacteria, the so-called mobilome. Such a transfer can mean that otherwise harmless bacteria can turn into lethal. This is because the mobilome often carries genes that are responsible for the production of toxins, i.e. toxic substances, and for resistance to antibiotics.</p><p>The research group has been able to identify a specific set of genes in S. aureus mobilome that confer immunity against infection with phages. This finding was possible thanks to Ume&aring; University's cryoelectron microscope. These genes interfere with the ability of phages to spread and multiply. This happens because a key protein expressed by one of the genes forms a structure around an important protein encoded by the phage's genome, thereby blocking the phage's ability to copy its DNA and thus unable to infect more bacteria.</p><p>"The discovery of this mechanism could be a door opener to understand several aspects of bacterial pathogenesis. On the one hand, we now understand better how resistant bacteria defend themselves against viruses. On the other hand, because these set of genes also encode for toxins and antibiotic resistance genes, it may therefore turn out that this is an important piece of the puzzle in the fight against antibiotic resistance," says Ignacio Mir-Sanchis.</p><p>The study is published in the scientific journal Nature Communications.</p>/en/news/ny-sidadiscovery-of-bacterias-defence-against-viruses-becomes-a-piece-of-the-puzzle-against-resistance_12074262//en/news/hello-magnus-what-is-up_12073051/Marie Peter's doctoral studies focus on identifying and characterizing various cellular proteins that play an important role in flavivirus infections. Now the goal is close as she will defend her thesis at Umeå University on 28 March.Thu, 20 Mar 2025 14:27:32 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/c951a21c64fe4f9289f9af61d5009122/marie_peters3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/c951a21c64fe4f9289f9af61d5009122/marie_peters3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/c951a21c64fe4f9289f9af61d5009122/marie_peters3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/c951a21c64fe4f9289f9af61d5009122/marie_peters3.jpg?mode=crop&amp;width=640 640w, /contentassets/c951a21c64fe4f9289f9af61d5009122/marie_peters3.jpg?mode=crop&amp;width=854 854w, /contentassets/c951a21c64fe4f9289f9af61d5009122/marie_peters3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Marie Peters is is a PhD student at the Department of Clinical Microbiology at Ume&aring; university.</p><span class="bildPhotografer"><span class="photo">Image</span>Emma Honkala</span></div></div><p class="quote-center">my excitement may have been heard in most of the department</p><h3>How does it feel?</h3><p>&ldquo;It was an incredible feeling to have the printed version of my thesis, as so many years have gone into this work. I excitedly waited by the door to receive the delivery and my excitement may have been heard in most of the department!&rdquo;</p><h3>What has been rewarding in being a PhD?</h3><p>&ldquo;The nicest thing about being a PhD student was to be able to follow a project the whole way from beginning to end and being able to perform new experiments depending on the different findings. I also think this was a great experience thanks to the support of my main supervisor Anna &Ouml;verby and co-supervisors Richard Lundmark and Emma Nilsson. They guided me through the process and invested a lot on time on helping me get to where I am. As a PhD I also had the opportunity to go to different international conferences, including American Society for Virology in Columbus, Ohio, and also European congress in virology in Gdansk, Poland, that were very fun and allowed me to connect with different people in my field.</p><h3>What have you been struggling with?</h3><p>&ldquo;A challenge has been the struggle of doing experiments, as only approximately 50 percent of the experiments were actually successful, which can sometimes be very frustrating . As a fun example I have managed to completely evaporate an agarose gel on accident trying to optimize an assay.&rdquo;</p><h3>What do you plan to do after your dissertation?</h3><p>&ldquo;When I have defended my Doctoral thesis, I have the great plan of taking a vacation in which I will watch reality TV shows to give my brain a break from all the thinking and hard work!&rdquo;</p><p>&ldquo;Thereafter, I will continue in Anna &Ouml;verby&rsquo;s Lab for a couple of months to finish some of the projects I am part of. More long term, I am planning on staying in academia and pursuing a postdoc, where I will hopefully be able to apply the knowledge I have gained during my PhD.</p><h3>What is the research about and your main result?</h3><p>&ldquo;Like all viruses, orthoflaviviruses have their own proteins, but they also hijack proteins from host cells to survive and multiply. While some of these proteins have been identified, many remain unknown. For this reason, the focus of my PhD thesis was to identify and characterize some of these proteins to in the future be able to use this knowledge for the development of antivirals (as little or no antivirals are available against most orthoflaviviruses).&rdquo;</p><p>&ldquo;I worked a lot with understanding the role of Nucleoporins (NUPs) in orthoflavivirus infection. They are a really cool group of proteins that in cells build up the nuclear pore complex that is involved in the transport of RNA and proteins across the nuclear envelope. While their cellular functions are well characterized, their role in orthoflavivirus infection is understudied. With the work I present in my thesis I show that these proteins are indeed important in infection in particular for the replication and translation stages of the viral life cycle.&rdquo;</p><p><a href="~/link/ec90d35857b945838ff4d0c8d67edb7f.aspx" target="_blank" rel="noopener">Read about Marie Peter's dissertation event</a></p>/en/news/hello-there-marie--success-and-challenges-on-the-path-to-becoming-a-virus-doctor_12064247//en/news/network-for-clinical-researchers-in-the-northern-healthcare-region_12057316/In the summer of 2024, a unique case of TBE infection was discovered in Västerbotten. A smaller study confirmed that there was virus in ticks on a limited part of Holmön island. Now the study is being expanded to investigate the occurrence of infection and virus in the county. Tue, 11 Mar 2025 10:30:54 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/880c36be88de4d1793768ea779d0cb46/fasting_jens_rydell_johner4.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/880c36be88de4d1793768ea779d0cb46/fasting_jens_rydell_johner4.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/880c36be88de4d1793768ea779d0cb46/fasting_jens_rydell_johner4.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/880c36be88de4d1793768ea779d0cb46/fasting_jens_rydell_johner4.jpg?mode=crop&amp;width=640 640w, /contentassets/880c36be88de4d1793768ea779d0cb46/fasting_jens_rydell_johner4.jpg?mode=crop&amp;width=854 854w, /contentassets/880c36be88de4d1793768ea779d0cb46/fasting_jens_rydell_johner4.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ticks can carry the TBE virus.</p><span class="bildPhotografer"><span class="photo">Image</span>Jens Rydell, John&eacute;r bildbyr&aring; AB</span></div></div><p class="quote-center">It is difficult to draw any major conclusions from the first study, as it is such a small data set</p><p>&ldquo;It is very exciting and also important to find out the situation in V&auml;sterbotten&rdquo;, says Anna &Ouml;verby Wernstedt, professor at the Department of Clinical Microbiology at Ume&aring; University.</p><p>In 2024, just under 400 cases of tick-borne encephalitis, TBE, were diagnosed in Sweden. In V&auml;sterbotten County, the disease is uncommon, 0&ndash;2 cases have been detected annually in the last ten years, and all are considered to have been infected in another county. The summer of 2024 was the first time that Region V&auml;sterbotten treated a person who was considered to have been infected in the county.</p><p>Anna &Ouml;verby Wernstedt has TBE as her main area of ​​research. Within a couple of weeks of the case in V&auml;sterbotten becoming known, she and her research team travelled to the island of Holm&ouml;n just outside Ume&aring;, where the person is suspected of having been bitten by a tick.</p><p>&ldquo;We learned about the case in August and in September we were on the island to collect ticks to examine. We thought it was important to look more closely at this and we needed to do it as quickly as possible to be able to get hold of some ticks, as the ticks lie down and sleep&rdquo;, she says.</p><p>The research team has conducted similar studies in southern Sweden, but not in V&auml;sterbotten County as there have been no cases before.</p><p>The current study was conducted in a small, limited area on Holm&ouml;n. Analyses show that there was virus in the ticks, but at very low levels. The study will be expanded during the summer of 2025.</p><p>&ldquo;It is difficult to draw any major conclusions from the first study, as it is such a small data set. In the new study, the collection of ticks will be expanded to more locations on Holm&ouml;n, but also to other islands in V&auml;sterbotten County, such as Norrbysk&auml;r. We will also seek ethical permission to study whether people have been exposed&rdquo;, says Anna &Ouml;verby Wernstedt.</p><h3>Different symptoms of the infection</h3><p>Most people who become infected with TBE do not have any symptoms at all, about a third get milder flu-like symptoms that go away within a week. However, some get more serious symptoms such as encephalitis with high fever, severe headache, confusion and possibly convulsions and paralysis.</p><p>&ldquo;There are very mild strains in Germany that only cause diarrhea and no neurological problems, while there are strains in Russia that cause a mortality rate of 20 percent. The European variant has a mortality rate of 0.5 percent of those who are diagnosed. But only a fraction become ill and hospitalized&rdquo;, says Anna &Ouml;verby Wernstedt.</p><p>Through the study that is being conducted, the researchers can characterize the virus that the ticks in V&auml;sterbotten County carry. Results are expected in a year.</p><p>&ldquo;By then we have collected ticks and analysed the samples that we have received, and hopefully blood samples from the people who move around on these islands. Then we can have a better picture of the situation&rdquo;.</p><p><strong>How should people act based on what we know today?</strong></p><p>&ldquo;At the moment we know very little. I cannot go out and say that everyone should get vaccinated when there has only been one case and we do not know if this strain is pathogenic and dangerous. We know too little, which is why we are doing this study&rdquo;.</p><p><strong>How did the virus come to V&auml;sterbotten County?</strong></p><p>&ldquo;We can only speculate. There is TBE in the Vasa region in Finland and it could have come with birds, that is the logical thing to assume, but we have no evidence right now. Humans are not affected by the spread of TBE, we usually say that humans are a dead-end host &ldquo;,says Anna &Ouml;verby Wernstedt.</p>/en/news/tbe-detected-in-vasterbotten-county--new-study-examines-virus-spread_12036628//en/news/join-the-one-ocean-expedition_12058479/Master’s or PhD students from Umeå University can apply to participate on a course about Arctic Future Pathfinders. The course take place over a month long voyage upon the ship S/S Statsraad Lehmkuhl across the north-west passage. Take this opportunity for an experience of a lifetime!Wed, 12 Mar 2025 10:53:45 +0100<div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="ac449520-8d6f-4814-a8aa-db568cca6b7f" data-contentname="One Ocean summary">{}</div><p>&nbsp;</p><p>As a Master&rsquo;s or PhD student from Ume&aring; University, you can apply to participate in the course &ldquo;<strong>Arctic Future Pathfinders &ndash; A journey through the Northwest Passage</strong>&rdquo;, which is part of the One Ocean Expedition. The expedition is based on the ship S/S Statsraad Lehmkuhl, which will take the participants through the north-west passage. Choose Group 1 or 2, depending on when and where you want to go. Take this opportunity for an experience of a lifetime!</p><p><strong>Group 1:</strong><br>Embark in Nuuk, Greenland and depart in Cambridge Bay, Canada. <br>The voyage is between 5 and 29 August 2025.</p><p><strong>Group 2:</strong><br>Embark in Cambridge Bay, Canada and depart in Whittier, Alaska.<br>The voyage is between 2 September and 4 October 2025.</p><h2 id="info0" data-magellan-target="info0">Sailing route</h2><p>Group 1:<br>05.08.2025 Departure from Nuuk, Greenland<br>13.08.2025 Arrival in Pond, Greenland<br>22.08.2025 Arrival in Gjoa Haven, Canada<br>29.08.2025 Arrival in Cambridge Bay, Canada<br>Flight from Cambridge Bay to Yellowknife<br>Flight from Yellowknife to Sweden</p><p>Group 2:<br>Flight from Yellowknife to Cambridge Bay, Canada<br>02.09.25 Departure Cambridge Bay, Canada<br>20.09.2025 Arrival in Nome, Alaska USA<br>04.10.2025 Arrival in Whittier, Alaska USA<br>Flight from Whittier to Sweden</p><h2 id="info1" data-magellan-target="info1">Application deadline</h2><p><strong>7 April, 2025</strong></p><p>Deadline to nominate to UiT is 15 April, and The Arctic Six will send in the suggestions from all four universities together on 11 April.</p><h2 id="info2" data-magellan-target="info2">Application</h2><p><a href="https://forms.office.com/e/Ti0wL8VDzB">Fill in the applcation form here</a></p><h2 id="info3" data-magellan-target="info3">About the course</h2><p>The course &ldquo;Arctic Future Pathfinders &ndash; A journey through the Northwest Passage&rdquo; is a 10 ECTS course for master&rsquo;s and PhD students. It is linked to Norway&rsquo;s Arctic Ocean 2050 initiative and the upcoming International Polar Year in 2032/33, aiming to train students and young academics to become essential Arctic researchers. It focuses on inter- and transdisciplinary collaboration competences and anticipatory skills.<br><a href="https://en.uit.no/one-ocean/masters-course">Read more here</a></p><h2 id="info4" data-magellan-target="info4">Background</h2><p>The One Ocean Expedition is a voyage organised by UiT &ndash; the Arctic University of Norway, which is one of universities within the Arctic Six collaboration. The Arctic Six has been tasked to nominate four participants from the other Arctic Six universities, one from Ume&aring; University, Lule&aring; University of Technology, University of Oulu, and University of Lapland (Nord university has a separate call).</p><p>Expedition costs and the charter flights to and from Yellowknife will be covered by UiT external funds. Travels to and from Sweden must be covered by the home department or the student.</p><h2 id="info5" data-magellan-target="info5">More information</h2><p>For further information about the course and expedition, see <a href="https://en.uit.no/one-ocean">the UiT website</a>.</p><p>You can also follow the ship and see the sailing route on <a href="https://www.oneoceanexpedition.com/">the One Ocean website</a>.</p>/en/news/join-the-one-ocean-expedition_12058479//en/news/canadas-new-arctic-foreign-policy-presented-at-umea-university_12054032/Umeå University recently hosted the Canadian Ambassador to Sweden, Jason LaTorre, for a presentation on Canada’s newly launched Arctic Foreign Policy (AFP). The event held on 6 February 2025 gathered Arctic researchers, university leadership, and representatives from multiple research centres to discuss shared challenges and explore collaboration opportunities between Canada and Sweden.Mon, 24 Feb 2025 17:00:59 +0100<div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="170b7808-b7bc-4661-ac80-a5188f2182fc" data-contentname="BILD CA/SW">{}</div><h2 id="info0" data-magellan-target="info0">A shared vision for the Arctic</h2><p>Canada&rsquo;s new AFP prioritises sustainable development, partnerships with Indigenous communities, and strengthened international cooperation to address the impacts of climate change. Given Ume&aring; University&rsquo;s strong profile in Arctic research and its active role in global Arctic networks such as the European Polar Board (EPB), The Arctic Six, and the University of the Arctic (UArctic), the institution was a natural choice for the Ambassador&rsquo;s visit.</p><p>&ldquo;Canada&rsquo;s new Arctic Foreign Policy aligns closely with challenges across the Arctic, including Sweden. International collaboration is essential to tackling shared priorities, from climate resilience and security to sustainable community development,&rdquo; says Keith Larson, Director of the Arctic Centre at Ume&aring; University.</p><h2 id="info1" data-magellan-target="info1">Strengthening Swedish-Canadian collaboration</h2><p>The event brought together a diverse group of researchers and policymakers, including Peter Sk&ouml;ld, Advisor on Arctic issues at Ume&aring; University, and Maria Grigoratou, Executive Secretary for the EPB, who has been based at the university since January.</p><p class="quote-center">The Ambassador&rsquo;s visit highlights the importance of international partnerships.</p><p>Ambassador LaTorre&rsquo;s presentation emphasised the potential for deepened cooperation between Canada and Sweden in Arctic research, education, and policy development. Discussions also addressed the shared responsibilities of Arctic nations in tackling urgent issues such as climate change, biodiversity loss, and the sustainable development of Arctic communities.</p><p>&ldquo;The Ambassador&rsquo;s visit highlights the importance of international partnerships. His presentation opens up new opportunities for collaboration between Ume&aring; University and Canadian institutions, allowing us to advance research and develop solutions to the challenges facing the Arctic,&rdquo; says Peter Sk&ouml;ld.</p><h2 id="info2" data-magellan-target="info2">Ume&aring; University&rsquo;s role in global Arctic policy</h2><p>The visit reaffirmed Ume&aring; University&rsquo;s position as a key player in Arctic research and policy discussions. As Sweden&rsquo;s Arctic University, Ume&aring; remains committed to fostering international dialogue and strengthening partnerships that contribute to sustainable development in the Arctic region.</p><p>With the challenges in the Arctic requiring urgent attention, events like these serve as catalysts for meaningful cooperation. As Canada and Sweden continue to champion sustainability and Indigenous engagement in the Arctic, their collaboration is set to play a vital role in shaping the region&rsquo;s future.</p>/en/news/canadas-new-arctic-foreign-policy-presented-at-umea-university_12054032//en/news/scilifelab-site-umea-celebrates-16-new-group-leaders_12053865/Medical doctors in infectious disease clinics were significantly more likely to be infected with the SARS-CoV2 virus than doctors with less patient contact. This is shown in a new study at Umeå University. One in five doctors working in infectious disease clinics were infected during the first and second waves of the pandemic in 2020.Mon, 24 Feb 2025 10:32:50 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/163bb02b3a234f43af0ef19cdc0f4246/fors_conolly_anne-marie_9878_220405_hkn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/163bb02b3a234f43af0ef19cdc0f4246/fors_conolly_anne-marie_9878_220405_hkn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/163bb02b3a234f43af0ef19cdc0f4246/fors_conolly_anne-marie_9878_220405_hkn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/163bb02b3a234f43af0ef19cdc0f4246/fors_conolly_anne-marie_9878_220405_hkn2.jpg?mode=crop&amp;width=640 640w, /contentassets/163bb02b3a234f43af0ef19cdc0f4246/fors_conolly_anne-marie_9878_220405_hkn2.jpg?mode=crop&amp;width=854 854w, /contentassets/163bb02b3a234f43af0ef19cdc0f4246/fors_conolly_anne-marie_9878_220405_hkn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Anne-Marie Fors Connolly, medical doctor and associate professor at Ume&aring; University</p><span class="bildPhotografer"><span class="photo">Image</span>Hans Karlsson</span></div></div><p class="quote-center">an important contribution to improving future pandemic management</p><p>&ldquo;The results highlight the importance of effective protective procedures and vaccination programmes for healthcare personnel during future pandemics. Our findings indicate that occupational exposure is an important risk factor for infection, says Anne-Marie Fors Connolly, medical doctor and associate professor at Ume&aring; University and the study's senior author.</p><p>In a national study led by Ume&aring; University, researchers have examined the risk of different clinical specialties among doctors testing positive for SARS-CoV-2, which caused COVID-19, during the pandemic. The study shows that infectious disease doctors, that is, those who worked in infectious disease clinics, were at the highest risk in 2020. This was especially the case during the first and second waves of the pandemic.</p><p>After infectious disease doctors, geriatric medicine and emergency medicine doctors were at the highest risk of infection compared to doctors with no to little patient contact. Among doctors who worked in infectious disease clinics, one in five, 20.2 percent, were infected in 2020. Among doctors with little patient contact, fewer than one in ten, 8.7 percent, were infected.</p><p>Vaccination clearly reduced the risk of testing positive for SARS-CoV-2. The study shows that vaccination programmes for high-risk groups in healthcare are crucial for protecting personnel.</p><p>&ldquo;Our result is an important contribution to improving future pandemic management and protective measures for healthcare personnel,&rdquo; says Anne-Marie Fors Connolly.</p><p>The study included data from over 35,000 publicly employed doctors in Sweden between February 2020 and March 2022. Researchers analysed the association between clinical specialty and the risk of testing positive for SARS-CoV-2.</p><p>The study was published in the scientific journal Scandinavian Journal of Public Health.</p><p><em>The study was conducted using data from Swedish national registries and the Swedish Municipalities and data from Swedish healthcare (Regionen). It was funded by Region V&auml;sterbotten ALF-fonden, MIMS, Kempefonden, Hj&auml;rt-Lungfonden and Petrus and Augusta Hedlunds Stiftelse.</em></p>/en/news/infectious-disease-specialists-most-exposed-during-the-pandemic_12051521//en/news/new-knowledge-about-cell-division-with-data-driven-techniques_12047410/Research from Umeå University paves the way for a quantitative data analysis method to study the cell division process in individual cells. The improved resolution will promote advanced cell analysis in the human body, especially in cases of incorrect cell division such as in the context of cancer.Wed, 28 May 2025 14:28:01 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5549-250130-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5549-250130-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5549-250130-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5549-250130-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5549-250130-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5549-250130-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Can we better distill biological knowledge about the cell out of large data sets? This question is a driving force in Johan Henriksson's research.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">The aim is to discover new unexpected biological patterns</p><p>&ldquo;We did not get the results we expected! But the study fortunately gave us a better understanding of the genome and how it can be measured when sequencing using transposons, a type of genetically modified mobile gene sequence. The transposons behave differently during cell division and this can be used, among other things, to follow the cell division process&rdquo;, says Johan Henriksson, research fellow at the Department of Molecular Biology at Ume&aring; University.</p><p>Every organ in the body is built from a large number of different cells, each of which performs different functions. Therefore, it is important to be able to study the cells individually. Even in the early stages of biological science, this was possible using microscopy, but it was limited to studying a maximum of five or ten genes at a time.</p><p>Advanced single-cell methods began to be used in the 2010s and have revolutionized the ability to efficiently count a large number of information-bearing molecules in the cell. The method relies on sequencing to study all (over 20,000) genes in a single cell. Nowadays, it is also possible to study millions of cells, one at a time, and this generates an enormous amount of data.</p><p>Studies of single cells do not need to be based on a hypothesis because no prior selection of genes is needed. This is called a &ldquo;data-driven&rdquo; approach, in that the collected data rather than a hypothesis guides the research direction and results.</p><p>&ldquo;The aim is to discover new unexpected biological patterns, which can lead to new research questions&rdquo;, says Johan Henriksson,</p><p>However, this comes with two major problems: We are now simply drowning in data and the technology is expensive. This was an important driving force for the research project that Johan Henriksson and his group started. Questions they asked themselves were: If the method is so expensive, how can it be used in a better way? What else can we tell from the data that we had not thought of before?</p><p>One theory was that it would be possible to measure the length of telomeres &ndash; DNA structures that form the ends of our chromosomes and protect them. Every time a cell divides, the telomeres become shorter. When they become too short, the cell can no longer divide; it becomes inactive or the genome is damaged, which can transform it into a cancer cell.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5561-250130-mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5561-250130-mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5561-250130-mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5561-250130-mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5561-250130-mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5561-250130-mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Johan Henriksson discusses an experiment with postdoctoral fellows Iryna Yakovenko and Jyoti Verma.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>However, the project did not go as planned. The initial analysis of the data looked promising, but the more data that was analyzed, the more contradictions were noticed.</p><p>&ldquo;After an intensive hunt for data from other labs, which can now be easily downloaded and compared, our team became desperate. Instead, we began to focus on investigating which other biological factors could affect the telomere length measurement&rdquo;, says Johan Henriksson.</p><p>The data analysis forced the researchers to pay close attention to details in previous research on telomeres. For example, the expected sequence of human telomeres &ndash; repeated DNA sequences of TTAGGG &ndash; is also found in other parts of the genome. Furthermore, the telomere is not a perfect repeat of TTAGGG, or a repeat at all. Rather, the telomere model is now so dated and oversimplified that it may actually be counterproductive.</p><p>Advanced sequencing technology has provided new data on the telomere sequence, but it is complex and difficult to interpret. The interpretation is also affected by how the measurement is performed. Johan Henriksson believes that the technique for analyzing genomes from single cells (ATAC-seq) needs to be reevaluated. ATAC-seq uses a type of genetically modified mobile gene sequence, called a transposon, to cut up the DNA into small pieces that can be sequenced.</p><p>&ldquo;Based on some rather complicated experiments, it turned out that the transposon neither duplicates local DNA as previous research suggests, nor does it seem to chop up the telomere as much as other parts of the genome. Measuring telomere length was simply not possible with this approach&rdquo;, says Johan Henriksson.</p><p>In another study, the researchers have already used the measurement method to locate a new, unexplored state in T cells that appears to be interesting for immunotherapy, a type of cancer treatment where the body's own immune system is used to fight cancer.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5589-250130-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5589-250130-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5589-250130-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5589-250130-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5589-250130-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/abbf2c8d69b24e3fa93a6e90505f9ab3/henriksson_johan_5589-250130-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Johan Henriksson lab works interdisciplinary in areas from computer science to molecular biology.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div>/en/news/new-knowledge-about-cell-division-with-data-driven-techniques_12047410//en/news/minute-of-silence-and-flag-at-half-mast-to-honour-the-victims-in-orebro_12047008/Umeå University participates in a national minute of silence to honour the victims of the school shooting in Örebro and flies the flag at half-mast on campus in Umeå.Mon, 10 Feb 2025 16:10:31 +0100<p>"What was not allowed to happen has happened and the whole country mourns with the victims. 4 February 2025 will forever mark a dark day in Swedish history. To honour the victims who never came home to their loved ones, I want to invite everyone across our country to gather for a minute of silence," says Prime Minister Ulf Kristersson on the government website.</p><h2 id="info0" data-magellan-target="info0">Ume&aring; University participates</h2><p>The government is calling for a national minute of silence at 12.00 on Tuesday 11 February.</p><p>The university management at Ume&aring; University calls on all students and staff to participates. Ume&aring; University will also fly a flag at half-mast at the campus pond on Tuesday, also at the request of the government.</p>/en/news/minute-of-silence-and-flag-at-half-mast-to-honour-the-victims-in-orebro_12047008//en/news/icelab-invites-project-project-proposals_12040412/IceLab invites multidisciplinary research teams to propose projects for a shared postdoctoral fellow, funded by Kempestiftelserna. Project proposals can now be submitted, until May 19th. An information pitch will be given February 12th at 12:00 in KBC Glasburen to hear more about the program during the IceLab Lunch Pitch. Mon, 03 Feb 2025 17:16:14 +0100<p>Researchers working in teams of two or more are encouraged to submit innovative multidisciplinary project proposals as part of this funding call. The initiative aims to foster projects that leverage collaboration across different fields and research methods. Funding will be awarded to three projects, each receiving support for a two-year postdoctoral fellowship. These shared postdoctoral fellows, guided by multidisciplinary research teams from Ume&aring; University or the Swedish University of Agricultural Sciences, will help turn innovative ideas into impactful research collaborations.</p><p>The Integrated Science Lab (IceLab) will host the selected fellows, providing an interdisciplinary environment where daily interactions with IceLab researchers fuel collaboration and discovery. IceLab fosters exploration across traditional disciplinary boundaries by integrating theoretical, computational, and empirical approaches. Supervising project teams will become IceLab affiliates and, when relevant, connect to Stress Response Modeling at IceLab, a Swedish Research Council-funded excellence center.</p><h3>Information given during the IceLab Lunch Pitch February 12th</h3><p>IceLab invites you to join an information meeting on the call on February 12th, in KBC Glasburen, during the first IceLab Lunch Pitch of the year (<a href="~/link/4b90cd2071af4935b86dcbeb9d8dd71b.aspx">link to event</a>). Martin Rosvall, Professor at the Department of Physics and director of IceLab, will encourage researchers to submit a project proposal and be available to answer any questions about the call. Register in advance if you are interested in attending.</p><p>The deadline to submit project proposals is May 19th. More information can be found on IceLab's website (<a href="/en/icelab/career-and-education/icelab-multidisciplinary-postdoctoral-programme/">link to information on the call</a>).</p>/en/news/icelab-invites-project-project-proposals_12040412//en/news/2024-mims-clinical-research-fellowships-awarded_12042093/The Laboratory for Molecular Infection Medicine Sweden, MIMS, has announced the awardees of the national Clinical Research Fellowship programme 2024. Vanja Lunberg Wiraeus at Gothenburg University and Anne Tuiskunen Bäck at Umeå University receive fellowships to conduct research on immune defects of newborns and viral pathogenesis during myocarditis, respectively.Fri, 07 Feb 2025 10:28:36 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture></picture></div><div class="bildText"><p>Vanja Lundberg Wiraeus at Gothenburg University is one of the award winners.</p><span class="bildPhotografer"><span class="photo">Image</span> Karolina Th&ouml;rn</span></div></div><p>Vanja Lundberg Wiraeus is an immunologist at Gothenburg University and a paediatric resident at Queen Silvia Children&rsquo;s Hospital in Gothenburg, where she has been involved in treating patients with Inborn Errors of Immunity (IEI). &nbsp;</p><p>Following a medical degree and PhD in immunology at Gothenburg University, she focused on setting up a translational workflow to validate genetic findings in children with IEI, a group of immune system disorders that can result in severe infections, autoimmune diseases, inflammation, allergies or even cancer.&nbsp;<br>&nbsp;<br>In her MIMS CRF project, she will work with Emma Haapaniemi at the Centre for Molecular Medicine Norway, University of Oslo, and assess the effectiveness of the CRISPR correction technique as a personalized treatment for patients with IEI.&nbsp;<br>&nbsp;<br>&lsquo;&lsquo;I am honoured to receive the MIMS Clinical Research Fellowship, which will advance our research in gene therapy for patients that suffer from serious defects in their immune system. This project aims to evaluate the efficiency of CRISPR correction technique for various T cell defects," Vanja Lundberg Wiraeus says and continues:</p><p>"The MIMS Clinical Research Fellowship grant will give me the opportunity to continue my clinical practise, to see children with different IEIs and at the same time provide samples for gene correction to the lab of my collaboration partner Emma Haapaniemi. The primary goal of her lab is to develop a platform for gene correction technologies for IEIs, and the corrected cells will then be evaluated in our lab for function and safety. As there is no specific treatment for IEI patients, the development of gene therapy is important for a patient specific therapy with less side effects&rsquo;&rsquo;.&nbsp;<br><br>&lsquo;&lsquo;I congratulate Vanja and excited to work on this project with her. Collaborating with Oslo University Hospital and Queen Silvia Children&rsquo;s Hospital in Gothenburg allows us to gather a sufficient number of patients, which is crucial for studying rare diseases. Our goal is to make this gene correction technique clinically available to the patients. It is great that their hospital has advanced therapy medicinal products (ATMP) designated for children, which is perfect for our work on corrected stem cells," says Emma Haapaniemi, Group Leader, MD PhD, Oslo University Hospital.&nbsp;</p><p>She continues:<br>&nbsp;&nbsp;<br>"We are at a similar career stage, and Vanja&rsquo;s clinical expertise combined with my research expertise brings complementary strengths to this project. I believe that our synergy will lead to significant benefits for patients. This collaboration marks the beginning of a larger, long-term effort, and we are excited about the potential impact.&rsquo;&rsquo;&nbsp;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/072719da6dec42a48d8018119d99e72b/anne-tuiskunen-lab_9770-240828-mpn.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/072719da6dec42a48d8018119d99e72b/anne-tuiskunen-lab_9770-240828-mpn.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/072719da6dec42a48d8018119d99e72b/anne-tuiskunen-lab_9770-240828-mpn.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/072719da6dec42a48d8018119d99e72b/anne-tuiskunen-lab_9770-240828-mpn.jpg?mode=crop&amp;width=640 640w, /contentassets/072719da6dec42a48d8018119d99e72b/anne-tuiskunen-lab_9770-240828-mpn.jpg?mode=crop&amp;width=854 854w, /contentassets/072719da6dec42a48d8018119d99e72b/anne-tuiskunen-lab_9770-240828-mpn.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Anne Tuiskunen at Ume&aring; University and Region V&auml;sterbotten is&nbsp;one of the award winners.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>Anne Tuiskunen B&auml;ck is a cardiology resident and her research centers on clinical virology and metagenomics. She completed her PhD in medicine on the Dengue virus at the Karolinska Institute and the French Forces Institute of Tropical Medicine (IMTSSA). Her current research focuses on the genetic characterization of virus isolates from patients to better understand the role of viruses in disease progression, adopting a strongly translational, bench-to-bedside perspective. In her MIMS CRF project, she will particularly investigate the genetic diversity and pathogenesis of <em>Nephropathia Epidemica</em> (&ldquo;sorkfeber&rdquo; in Swedish), caused by the Puumala virus, and viral myocarditis, inflammation of the heart muscle.&nbsp;<br>&nbsp;<br>She will work with former MIMS Clinical Research Fellow Anne-Marie Fors Connolly to incorporate an epidemiological dimension into these studies.&nbsp; Additionally, she shares an interest in metagenomics with MIMS Investigator Laura Caroll at Ume&aring; University, with whom she is engaged in ongoing discussions to explore synergies and potential collaboration.&nbsp;<br>&nbsp;<br>&lsquo;&lsquo;I am deeply grateful for the MIMS fellowship, which strengthens my ability to pursue interdisciplinary and translational research at the intersection of cardiology and virology. One of my key projects investigates the genetic evolution of the Puumala virus in Sweden over time and space, aiming to better understand its virulence and links to human transmission, ultimately contributing to enhanced public health strategies. Another project focuses on viral myocarditis, a common cause of sudden cardiac death in young individuals, with the goal of improving diagnostics and risk prediction using biomarkers and genetic analysis," Anne Tuiskunen B&auml;ck says.&nbsp;</p><p>She continues:&nbsp;<br>&nbsp;&nbsp;&nbsp;<br>"The collaborative environment at MIMS aligns naturally with my research, and I look forward to exploring synergies with colleagues such as Anne-Marie Fors Connolly and Laura Carroll&rsquo;&rsquo;. <br><br>"I am delighted that Anne Tuiskunen B&auml;ck received the MIMS CRF. As a former MIMS CRF, it has been extremely helpful to my career and research network to participate in the MIMS and EMBL network, and I believe that Anne will have a similar positive and beneficial experience," Anne-Marie Fors Connolly, Associate Professor, MD PhD, former MIMS CRF, Ume&aring; University, says.</p><p>"I look forward to continuing my collaboration with Anne Tuiskunen B&auml;ck, from the established ongoing collaboration focusing on Puumala virus epidemiology; to the newly started collaborative initiative focusing on the risk of myocarditis following SARS-CoV-2 infection. Addressing these questions is critical for improving surveillance strategies and understanding the genetic drivers of PUUV outbreaks, and for improving diagnosis and treatment of myocarditis complications following infections."&nbsp;<br>&nbsp;<br>"I'm really excited about collaborating with Anne, particularly on some metagenomics-related projects, where we can combine our expertise in virology and bacterial bioinformatics. Viral metagenomics is a particularly hot topic right now, and Anne's subject matter expertise will be essential for these projects," says Laura Carroll, Associate Professor, PhD, MIMS Investigator, Ume&aring; University.<br>&nbsp;<br>MIMS Clinical Research Fellowships provide guaranteed research time and fund the fellow&rsquo;s research up to a total value of 3.2 million SEK.&nbsp;&nbsp;<br>&nbsp;<br>&ldquo;We are happy to welcome two new clinical fellows to the MIMS community. Their projects bridge basic and clinical research in two important areas of medicine, which is the aim of our program. They also illustrate how opportunities arise from international collaboration in molecular medicine, which is at the core of our partnership with the European Molecular Biology Laboratory, EMBL, and its Nordic Partnership,&rsquo;&rsquo; says Oliver Billker, Director of MIMS, Ume&aring; University.</p><p><em>MIMS receives funding from the Swedish Research Council, the Knut and Alice Wallenberg Foundation, the Kempe Foundations and Ume&aring; University to foster the next generation of outstanding researchers in infection medicine. It is the Swedish node in the EMBL network, to which it is connected through the Nordic EMBL Partnership for Molecular Medicine.&nbsp;</em></p>/en/news/2024-mims-clinical-research-fellowships-awarded_12042093//en/news/ukrainian-researchers-visited-umea-for-collaboration-and-inspiration_12041064/Ryo Morimoto unpacks many moving boxes from Germany and sets up snail aquariums while establishing his new laboratory at Umeå University. “I believe I might be the first researcher to introduce snails as an experimental system in Umeå,” he says enthusiastic with a smile.Thu, 09 Jan 2025 14:49:11 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0882-250107-mpn.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0882-250107-mpn.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0882-250107-mpn.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0882-250107-mpn.jpg?mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0882-250107-mpn.jpg?mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0882-250107-mpn.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ryo Morimoto collects snails from the aquarium. His passion lies in basic science, with a focus on unravelling the pathophysiology of various human diseases, which may also have implications for clinical medicine.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">having my own lab for the first time opens exciting opportunities</p><p>Snails offer a simplified perspective on the complexities of human immunity, making them a valuable model for understanding fundamental immune mechanisms. This approach allows him to carve out his own distinct research niche to pursue his scientific interest as a principle investigator.</p><p>&ldquo;There is fascinating evolutionary science to explore here in Ume&aring;, and having my own lab for the first time opens exciting opportunities,&rdquo; says Ryo Morimoto, research fellow in the Department of Molecular Biology and Group Leader at the Laboratory for Molecular Infection Medicine Sweden, MIMS, at Ume&aring; University.</p><h2 id="info0" data-magellan-target="info0">Investigates evolution of immunity</h2><p>Ryo Morimoto investigates the evolution of the human adaptive immune system using a unique lens &ndash; non-conventional model organisms. Adaptive immunity is a cornerstone of vertebrate self-defence against pathogens. It emerged relatively recently on the evolutionary timescale, around 500 million years ago, coinciding with the emergence of vertebrates.</p><p>The human immune system has evolved to become highly sophisticated, yet its foundation is built on ancient features. Over time, it has developed intricate fine-tuning mechanisms to minimize the risks associated with adaptive immunity while maximizing its effectiveness. However, this refinement often obscures the ancient core features of adaptive immunity.</p><p>Ryo Morimoto&rsquo;s current project focuses on a family of enzymes that serve as critical evolutionary building blocks shaping adaptive immunity.</p><p>&ldquo;We employ a multidisciplinary approach that combines <em>in vitro</em> biochemistry of these enzymes, single-cell omics, advanced imaging, computational genomics, and <em>in vivo</em> techniques. Our goal is to uncover the fine-tuned mechanisms regulating physiological genome editing within the immune system,&rdquo; says Ryo Morimoto.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0963-250107-mpn.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0963-250107-mpn.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0963-250107-mpn.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0963-250107-mpn.jpg?mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0963-250107-mpn.jpg?mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0963-250107-mpn.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ryo Morimoto is establishing his new lab at Ume&aring; University and is currently looking for a postdoc and a PHD student.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><h2 id="info1" data-magellan-target="info1">Passion for molecular biology</h2><p>Ryo Morimoto was born and raised in Japan. His passion for molecular biology was sparked during his middle school years.</p><p>&ldquo;I still remember being 14 or 15 years old, sitting in a science class instantly captivated when our teacher introduced the biochemistry and molecular biology behind cellular respiration,&rdquo; he recalls.</p><p>Over time, his curiosity expanded to encompass a broad range of life sciences, eventually leading him to enrol in medical school at the University of Tokyo. The university&rsquo;s strong research focus resonated deeply with Ryo. Early in his studies, he approached professor Takao Shimizu to request a spot in the lab so he could conduct experiments.</p><p>&ldquo;That is how I spent my mornings, evenings, and weekends &ndash; immersed in the lab outside of medical classes! The only time I was not in the lab was when I was hiking in the Japanese mountains. Research became my hobby,&rdquo; he says with a smile.</p><p>After graduating from medical school in 2011, Ryo completed two years of clinical residency in teaching hospitals, gaining experience across various fields of medicine. He found clinical work deeply rewarding and enjoyed being a physician. However, the cases that stayed with him most were those where modern medicine offered little help &ndash; patients for whom no specific treatment existed or where even a correct diagnosis was elusive.</p><p>&ldquo;It was both serious and frustrating for me. I wanted to do something for these people, to contribute long term by understanding the pathophysiology of diseases through basic science,&rdquo; Ryo reflects.</p><h2 id="info2" data-magellan-target="info2">Choosing between two careers</h2><p>Ryo realized that while he could make a difference as a medical doctor, his true passion lay in exploring the molecular and biochemical mechanisms underlying diseases. This led him to pursue a PhD in biochemistry at the University of Tokyo. His doctoral research delved into lipidomics, with a focus on phospholipid metabolism and inflammatory lipid mediators.</p><p>&ldquo;I was curious about understanding the regulatory mechanisms that drive diversity in biological processes and towards the end of my PhD, I began exploring ways to apply this interest to more<em> in vivo</em> model systems,&rdquo; Ryo says.</p><p>At a multidisciplinary conference in Berlin, he attended a talk by professor Thomas Boehm, who would later become his postdoctoral supervisor. The presentation described the alternative adaptive immunity found in jawless vertebrates.</p><p>&ldquo;It was love at first sight. I was completely captivated by the idea.&rdquo;</p><p>Supported by a prestigious JSPS overseas fellowship, he could move to Freiburg in Germany, to join the Max Planck Institute of Immunobiology and Epigenetics as a postdoctoral fellow,</p><p>&ldquo;Not only did I enter a new scientific field, but it was also my first time living outside of Tokyo!&rdquo; he says.</p><h2 id="info3" data-magellan-target="info3">Uses unusual model organisms</h2><p>Over the following seven years, Ryo focused on studying the evolutionary trajectory of vertebrate adaptive immunity. His research centred on the diversification of anticipatory antigen receptors in jawless vertebrates, particularly the European brook lamprey. It was essential to compare animal models at different stages of evolution. In addition to lamprey, he also worked with other model organisms, such as sharks, zebrafish, and mice.</p><p>The studies provided critical insights into the implications of alternative adaptive immunity for the human immune system. His most important discovery was providing molecular evidence that an enzyme called cytidine deaminase is responsible for the somatic assembly of lamprey&rsquo;s alternative antigen receptors in their adaptive immunity.</p><p>&ldquo;Interestingly, the enzyme that belongs to the same family plays a central role in humans for antibody class switching and somatic hypermutation, highlighting the deeply rooted evolutionary function of this enzyme family in adaptive immunity,&rdquo; Ryo says.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0898-250107-mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0898-250107-mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0898-250107-mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0898-250107-mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0898-250107-mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0898-250107-mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>One of the unusal model organisms is the Water snail,<em> Biomphalaria glabratais. </em>Its native distribution includes the Caribbean. One snail can lay 14,000 eggs during its whole life span, which is 2 years. Every month a new generation is born and it grows to the size of 1-2 centimeters.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><h2 id="info4" data-magellan-target="info4">Forms own group in Sweden</h2><p>In 2022, Ryo advanced to project leader within the same research group. This shift made him more conscious of his responsibilities as a team leader, transitioning from a focus on bench work to guiding and supporting others.</p><p>Ryo sought for the next step to establish himself as an independent researcher. While searching for opportunities, he came across an interesting advertisement online for a position at the Laboratory for Molecular Infection Medicine Sweden, MIMS, at Ume&aring; University in Northern Sweden.</p><p>Fast forward to today; Ryo has been working in Ume&aring; for more than half a year. He thinks that the quiet environment here allows him to focus well on his research and plan the next steps to let his team grow.</p><p>He is also impressed by the friendly and inclusive culture in Sweden and does not miss the constant buzz and stimulation of a big city like Tokyo.</p><p>&ldquo;I adapted to life in Europe much better than I initially expected. Before leaving Japan, I thought I might return after just a few months or a couple of years. But I find myself still here, well settled in the society!"</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0957-250107-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0957-250107-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0957-250107-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0957-250107-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0957-250107-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/d0221110111b400b9d71054381098400/ryo_morimoto-0957-250107-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ryo Morimoto is taking care of snail's food. Adults in captivity can be fed with lettuce. The young ones are given dried salad in powder form.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><div class="mediaflowwrapper bildlink"><div class="bildText">&nbsp;</div></div>/en/news/the-evolution-of-the-immune-system--love-at-first-sight_12028881//en/news/sweden-invests-in-arctic-and-polar-research_12021317/The Swedish government’s 2025–2028 research bill designates polar research as a strategic national priority, emphasising climate change, geopolitics, and sustainability. The bill underscores Sweden's role in shaping the future of the polar regions. For Umeå University (UMU), Luleå University of Technology (LTU), the Swedish Polar Research Secretariat (SPRS), and the Swedish Centre for the Arctic and Antarctic, this presents a vital opportunity to advance research of societal relevance.Mon, 23 Dec 2024 07:00:08 +0100<h2 id="info0" data-magellan-target="info0">Ume&aring; University and Lule&aring; University of Technology, together with Polar, lead the way in Polar Research</h2><p>The Swedish Centre for the Arctic and Antarctic establishment in December 2024 marks a new chapter in Sweden&rsquo;s dedication to polar research. This collaboration builds on a legacy of pioneering Arctic research by bringing together the expertise of UMU, LTU, and the SPRS. The centre was established as a leading platform for research and education in polar regions. The centre promotes interdisciplinary cooperation and contributes to a sustainable future in the Arctic and Antarctic. Supported by the latest research bill, the Centre is uniquely positioned to address urgent challenges such as climate change, sustainability, and geopolitical dynamics in polar regions.</p><p>&ldquo;This research bill demonstrates the government&rsquo;s recognition of the importance of investing in research that sheds light on the consequences of climate change and geopolitical shifts in polar regions. Building on our history of impactful research and interdisciplinary initiatives, we look forward to playing a key role at the Arctic Centre by contributing knowledge and fostering collaborations that benefit societal development in the Arctic,&rdquo; says Keith Larson, Director of the Arctic Centre at Ume&aring; University.</p><p class="quote-center">Arctic Six is a crucial platform where we can collaborate across national borders to tackle major Arctic issues, from climate change to social sustainability</p><h2 id="info1" data-magellan-target="info1">Arctic Six as a Catalyst for Regional Research</h2><p>Ume&aring; University and LTU are part of Arctic Six, a network of six leading Nordic universities focused on Arctic research. Arctic Six has successfully coordinated large-scale projects on climate resilience and Indigenous community adaptation, creating frameworks that have informed policymaking across the Nordic region. Its ongoing initiatives include innovative collaborations on renewable energy solutions tailored for Arctic conditions. The network is designed to mobilise resources, expertise, and innovation to address the unique challenges of the Arctic region, including climate adaptation and social sustainability.</p><p>&ldquo;Arctic Six is a crucial platform where we can collaborate across national borders to tackle major Arctic issues, from climate change to social sustainability. As Sofie Eriksson, Member of the European Parliament, aptly noted in an EU plenary debate on December 16th, &lsquo;The Arctic Six [&hellip;] where universities have joined forces to create a platform for research and education that makes a real difference. Together with government agencies and local communities, they anchor themselves in the realities of everyday life.&rsquo; This alignment strengthens our ability to create tangible societal benefits through collaboration,&rdquo; says Dag Avango,&nbsp;Director of The Centre for the Arctic and Antarctic at LTU and Director of Arctic Six.</p><h2 id="info2" data-magellan-target="info2">Innovative Infrastructure for Polar Research</h2><p>The research bill includes support for Polar Connect, a fibre-optic cable through the Arctic that will significantly enhance Sweden&rsquo;s digital infrastructure and capacity for climate monitoring. Additionally, the government is preparing to construct a new research icebreaker to secure Sweden&rsquo;s year-round access to the Arctic, ensuring continued advancements in research and strategic interests.</p><p class="quote-center">The proposed investments [are] creating opportunities for deepened collaborations and research focusing on the populated Arctic and its challenges</p><p>"At Ume&aring; University, we recognise the importance of investments in polar infrastructure as a platform for research. At the same time, the proposed investments are broader, creating opportunities for deepened collaborations and research focusing on the populated Arctic and its challenges. This provides a chance to prioritise societal development and sustainability, key areas for contributing to a resilient future for Arctic communities," says Dieter M&uuml;ller, Pro Vice-Chancellor of Ume&aring; University.</p><h2 id="info3" data-magellan-target="info3">Toward a Sustainable Future</h2><p>The Arctic Centre at Ume&aring; University welcomes the government&rsquo;s investments as a critical step in strengthening Sweden&rsquo;s leadership in Arctic research. Strategic collaborations, such as the Swedish Centre for the Arctic and Antarctic and the Arctic Six, empower researchers to tackle the Arctic's pressing challenges and improve the lives of its inhabitants. These collaborations highlight the importance of regional cross-cutting research expertise in shaping our shared global future.</p>/en/news/sweden-invests-in-arctic-and-polar-research_12021317//en/news/new-members-from-umea-university-in-the-swedish-research-councils-scientific-councils_12021283/Fredrik Almqvist, Sofia Lundberg, and Jörgen Johansson from Umeå University have been appointed as new members of the Swedish Research Council's three scientific councils. The mandate period runs from 2025 to 2027.Fri, 20 Dec 2024 10:12:39 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/ad0d005064f043a0b35b3709a8309c1a/vr_kollage3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ad0d005064f043a0b35b3709a8309c1a/vr_kollage3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ad0d005064f043a0b35b3709a8309c1a/vr_kollage3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ad0d005064f043a0b35b3709a8309c1a/vr_kollage3.jpg?mode=crop&amp;width=640 640w, /contentassets/ad0d005064f043a0b35b3709a8309c1a/vr_kollage3.jpg?mode=crop&amp;width=854 854w, /contentassets/ad0d005064f043a0b35b3709a8309c1a/vr_kollage3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Fredrik Almqvist, Sofia Lundberg and J&ouml;rgen Johansson.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>The Swedish Research Council has three scientific councils responsible for allocating research funding, as well as following up and evaluating research within their respective subject areas. The following persons from Ume&aring; University were recently appointed new members:</p><p><strong>Fredrik Almqvist</strong>, Professor at the Department of Chemistry, Council for Natural and Engineering Sciences</p><p><strong>Sofia Lundberg</strong>, Professor at Ume&aring; School of Business, Economics and Statistics, Council for Humanities and Social Sciences</p><p><strong>J&ouml;rgen Johansson</strong>, Professor at the Department of Molecular Biology, Council for Medicine and Health</p><p>At the same time, <strong>Niklas Arnberg</strong>, Professor at the Department of Clinical Microbiology, was re-elected as a member of the Swedish Research Council's board, and <strong>Charlotte H&auml;ger</strong>, Professor at the Department of Community Medicine and Rehabilitation, was re-elected as a member of the Council for Medicine and Health.</p><p><a href="https://www.vr.se/english/just-now/news/news-archive/2024-12-17-new-members-of-the-swedish-research-councils-board-and-scientific-councils-2025-2027.html">Read more on the Swedish Research Council&rsquo;s website</a> (vr.se)</p>/en/news/new-members-from-umea-university-in-the-swedish-research-councils-scientific-councils_12021283//en/news/research-schools-in-the-infection-field--grand-slam-to-umea_12020136/The Swedish Research Council is awarding Umeå University 16 million sek to two national research schools that will contribute to strengthening research competence in Sweden in the field of infection.Wed, 18 Dec 2024 15:45:30 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/32cc574582c7435e90b4f80fea7c5742/gruppbild_forskarskolor3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/32cc574582c7435e90b4f80fea7c5742/gruppbild_forskarskolor3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/32cc574582c7435e90b4f80fea7c5742/gruppbild_forskarskolor3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/32cc574582c7435e90b4f80fea7c5742/gruppbild_forskarskolor3.jpg?mode=crop&amp;width=640 640w, /contentassets/32cc574582c7435e90b4f80fea7c5742/gruppbild_forskarskolor3.jpg?mode=crop&amp;width=854 854w, /contentassets/32cc574582c7435e90b4f80fea7c5742/gruppbild_forskarskolor3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>From left: Louise Lindb&auml;ck, project coordinator, Annasara Lenman, the National Doctoral Programme in Infections and Antimicrobials, NDPIA. Fredrik Almqvist, Director of Ume&aring; Centre for Microbial Research, UCMR, and Marta Bally, Nationella forskarskolan i virusinfektioner och pandemier, NDP-VIP.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><p class="quote-center">it is fantastic that Ume&aring; is getting both schools</p><p>&ldquo;It feels wonderful! Antimicrobial resistance is one of our biggest societal problems and we now have a unique opportunity to address a complex issue from a broad perspective,&rdquo; says Annasara Lenman, associate professor lecturer at the Department of Clinical Microbiology at Ume&aring; University. She coordinated the application for the National Doctoral Programme in Infections and Antimicrobials, NDPIA.</p><p>This research school, which will now receive eight million over four years, builds on Ume&aring; University's long tradition of working with this type of research school. Over 700 doctoral students and postdoctoral fellows have participated in the National Doctoral Programme in Infections and Antibiotics, NDPIA, which was run during the period 2014-2024.</p><p>The second research school that will receive the same amount of funding focuses on viruses and pandemics.</p><p>&ldquo;There has been a long-standing desire from the research community to offer virus-specific education nationally. I am pleased that this school can contribute to meet this,&rdquo; says Marta Bally, associate professor at the Department of Clinical Microbiology at Ume&aring; University. She coordinated the application for the National Research School in Viral Infections and Pandemics, NDP-VIP.</p><h2 id="info0" data-magellan-target="info0">Close collaboration between schools</h2><p>The research schools have two different focuses within infection research &ndash; antimicrobial resistance then viruses and pandemics, but will still have close collaboration. Overall, they have the same foundation to build on and the same goals in mind. This means that many synergies will be possible and will result in a broad and effective course programme.</p><p>Together, the two schools will form an inspiring educational environment where doctoral students and postdoctoral fellows from all over Sweden are offered advanced courses. An important part of the education will be practical workshops in the latest research methods and techniques.</p><p>To promote collaboration and expand the participants' networks, national meetings and conferences are arranged where participants can present their research and exchange ideas with others in the field.</p><h2 id="info1" data-magellan-target="info1">Several universities involved</h2><p>The research schools are run in collaboration with leading universities in Sweden. Through the collaboration, the schools connect research environments that study all aspects of infection biology, from molecular mechanisms to new methods for diagnostics, vaccine development, clinical studies and societal perspectives.</p><p>&ldquo;An interdisciplinary and One Health perspective is crucial for understanding complex problems such as antimicrobial resistance and the emergence of pandemics and for finding new and innovative solutions,&rdquo; says Annasara Lenman.</p><h2 id="info2" data-magellan-target="info2">Ume&aring; strong player</h2><p>Ume&aring; University has invested a lot in infection research in recent years and the field has been one of the priority research areas at the university since 2024 through the Mastering Microbial Infections programme.</p><p>There is a very active community in microbial research within the Ume&aring; Centre of Microbial research, UCMR, which is further strengthened by programmes such as the Wallenberg Centre for Molecular Medicine, WCMM, Data Driven Life Science, DDLS, and Molecular Infection Medicine Sweden, MIMS, which recruit young promising researchers. The schools fit perfectly into this environment.</p><p>UCMR is hosting the new research schools. However, the courses will be held all over Sweden.</p><p>&ldquo;Ume&aring; University is a strong national player in infection research and it is fantastic that Ume&aring; is getting both schools! This means that we can continue to educate a new generation of researchers who can contribute to Sweden being better prepared for future pandemics and infection threats, says Fredrik Almqvist, professor at the Department of Chemistry at Ume&aring; University and director of UCMR.</p><p><a href="https://www.vr.se/english/applying-for-funding/decisions/2024-06-20-doctoral-programme-grant-within-the-infection-area.html" target="_blank" rel="noopener">Read more about the grant</a></p>/en/news/research-schools-in-the-infection-field--grand-slam-to-umea_12020136//en/news/umea-university-joins-european-alliance_12019141/The Deputy Head of Mission at the Swiss Embassy, Vincent Juillerat, visited Umeå University to discuss collaborations on the effects of climate change in the Arctic and the Alps. The focus was on the role of research in sustainable development, the integration of Indigenous knowledge, and global partnerships. The visit strengthens the ties between Switzerland and Sweden, paving the way for future collaborations in research and policy development.Mon, 16 Dec 2024 15:49:31 +0100<h2 id="info0" data-magellan-target="info0">Swiss Embassy Deputy Explores Ume&aring; University&rsquo;s Arctic Research</h2><p>On 9&ndash;10 December, Vincent Juillerat, Deputy Head of Mission at the Swiss Embassy in Stockholm, visited Ume&aring; University to engage with its leading Arctic research units. This visit underscored the shared challenges and opportunities for collaboration between Switzerland and Sweden, particularly in addressing climate change impacts on ecosystems, tourism, and geopolitical dynamics in the Arctic and Alpine regions.</p><h2 id="info1" data-magellan-target="info1">Strengthening Connections Between the Alps and the Arctic</h2><p>Switzerland and Sweden, though geographically distinct, face similar environmental and societal challenges in their Arctic and Alpine regions. These include the impacts of climate change on ecosystems, sustainable tourism, and integrating Indigenous knowledge into policymaking. Pro-Vice-Chancellor Dieter M&uuml;ller welcomed Juillerat, emphasising Ume&aring; University&rsquo;s strategic role in Arctic research and its potential to drive collaborative solutions.</p><p>&ldquo;Arctic research requires global partnerships to succeed. Through dialogue with international actors like the Swiss Embassy, we strengthen the connections needed to address the complex challenges facing the Arctic today,&rdquo; said Dieter M&uuml;ller.</p><p class="quote-center">Arctic research requires global partnerships to succeed</p><p>Juillerat&rsquo;s visit provided a comprehensive overview of Ume&aring; University&rsquo;s contributions to Arctic research, highlighting its leadership in the <strong>Arctic Six</strong> network and its role as the new host of the <strong>European Polar Board</strong>. These initiatives exemplify the university&rsquo;s commitment to linking research, policy, and sustainable development.</p><h2 id="info2" data-magellan-target="info2">From Research Insights to Policy Impact</h2><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/8c7037ef684c456cb8ef770714c729e7/larsson_keith_8437_180110_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/8c7037ef684c456cb8ef770714c729e7/larsson_keith_8437_180110_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/8c7037ef684c456cb8ef770714c729e7/larsson_keith_8437_180110_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/8c7037ef684c456cb8ef770714c729e7/larsson_keith_8437_180110_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/8c7037ef684c456cb8ef770714c729e7/larsson_keith_8437_180110_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/8c7037ef684c456cb8ef770714c729e7/larsson_keith_8437_180110_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Keith Larson, director of the Arctic Centre at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>The program featured a keynote discussion by Keith Larson, Director of the <strong>Arctic Centre</strong>, who highlighted the importance of interdisciplinary approaches to Arctic challenges. Larson&rsquo;s presentation explored how collaborative research can inform policy and drive solutions in the rapidly changing Arctic environment. This discussion set the stage for a broader exchange of ideas between Ume&aring; University researchers and their Swiss counterparts.</p><p>P&auml;r Bystr&ouml;m, Director of the <strong>Climate Impacts Research Centre</strong>, provided a detailed analysis of climate change effects on Arctic ecosystems. He emphasised the interconnected changes in temperature, precipitation, and vegetation, linking these to Arctic lakes' browning and fish communities' shifts. Bystr&ouml;m also stressed the increasing importance of winter research in understanding these dynamics.</p><h2 id="info3" data-magellan-target="info3">Indigenous Perspectives in Arctic Research</h2><p>A significant focus of the visit was integrating Indigenous knowledge into Arctic research. Kristina Selin MacNeil presented the work of <strong>V&aacute;rdduo &ndash; Centre for S&aacute;mi Research</strong>, Sweden&rsquo;s only S&aacute;mi research centre. She highlighted the importance of incorporating S&aacute;mi culture, history, and language into studies of the Arctic, particularly in addressing contentious regional issues. Juillerat expressed a strong interest in the challenges of recognising Indigenous perspectives and rights in policymaking.</p><p>&ldquo;The inclusion of Indigenous knowledge is crucial for developing sustainable and equitable Arctic policies,&rdquo; noted Keith Larson, underscoring V&aacute;rdduo&rsquo;s contributions to interdisciplinary approaches and policy-relevant research.</p><h2 id="info4" data-magellan-target="info4">Shared Interests in Tourism and Security</h2><p>Dieter M&uuml;ller drew parallels between the Arctic and Swiss Alps' tourism sectors, emphasising the need for sustainable strategies in these environmentally sensitive regions. Additionally, Paul Schmidt addressed the Arctic&rsquo;s growing geopolitical significance, highlighting the importance of fostering stability and international cooperation.</p><p>Linda Lundmark showcased the <strong>Arctic Graduate School</strong>, an initiative preparing early-career researchers to tackle the Arctic's complexities through innovative, interdisciplinary approaches.</p><h2 id="info5" data-magellan-target="info5">A Pathway to Future Collaboration</h2><p>The visit concluded by reaffirming the shared interests and mutual goals between Switzerland and Sweden. Both countries recognise the critical role of research in addressing global environmental and societal challenges. The dialogue reinforced Ume&aring; University&rsquo;s position as a hub for Arctic research and a key player in fostering international partnerships.</p><p>Looking ahead, the Swiss Embassy and Ume&aring; University aim to explore joint activities to strengthen our shared research agendas.</p>/en/news/building-bridges-between-the-alps-and-the-arctic_12018640//en/news/understanding-the-spread-of-animal-infections--prevent-the-next-pandemic_12017600/The PANDASIA project aims to increase our understanding of how diseases that spread between animals and humans – take the step from animals to humans. It is this type of transmission that is often behind new pandemics. Umeå researcher Henrik Sjödin is participating in the large European project that focuses on Thailand in Southeast Asia.Fri, 13 Dec 2024 14:11:35 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/ima1494443.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/ima1494443.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/ima1494443.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/ima1494443.jpg?mode=crop&amp;width=640 640w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/ima1494443.jpg?mode=crop&amp;width=854 854w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/ima1494443.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>BViruses can spread from animals to humans, and bats are an example of a host animal.</p><span class="bildPhotografer"><span class="photo">Image</span>John&eacute;r Bildbyr&aring; AB, Jens Rydell</span></div></div><p>Zoonotic spillover means that a disease or infectious agent is transmitted from animals to humans. Viruses, bacteria or parasites that previously only existed in animals can infect humans through changes or opportunities for contact. It occurs through direct contact with animals, through food or through vectors such as mosquitoes, ticks, or bats. The process is central to the emergence of many new infectious diseases, including pandemics such as influenza, SARS, MERS and COVID-19.</p><p>"Within PANDASIA, we investigate the socio-ecological mechanisms behind viral zoonotic spillover. The goal is to identify strategies to reduce the frequency of spillovers and the risk of pandemics through better knowledge, preparations and preventive targeted efforts," says Henrik Sj&ouml;din, researcher at the Department of Public Health and Clinical Medicine at Ume&aring; University.</p><h2 id="info0" data-magellan-target="info0">Special focus on Thailand</h2><p>PANDASIA stands for "Pandemic Literacy and Viral Zoonotic Spillover Risk at the Frontline of Disease Emergence in Southeast Asia to Improve Pandemic Preparedness" and is mainly funded by the EU through Horizon Europe and by UK Research and Innovation. It is a collaboration between several research institutes in Europe and Thailand, and is led by researcher Hans Overgaard at the Norwegian University of Environmental and Biosciences.</p><p>"The project is concentrated in Southeast Asia, with a particular focus on studying preliminary stages of disease outbreaks in high-risk environments in Thailand, where data collection and field studies are combined. We want to understand the risks along gradients from natural environments to rural and urban areas, where human activity meets natural ecosystems," says Henrik Sj&ouml;din.</p><h2 id="info1" data-magellan-target="info1">Mathematical models of spillover</h2><p>Henrik's research group in Ume&aring; plays a central role in modeling and analyzing the complex processes behind zoonotic spillover. To understand these mechanisms over both time and space, the group uses mathematical and quantitative models.</p><p>"We study ecological, evolutionary, sociological and epidemiological factors from a One Health perspective, which connects the health of people, animals and ecosystems."</p><p>Specifically, Henrik and his colleagues develop models based on data and empirical observations from the other research groups in the project.</p><p>"Our models function both as a tool for understanding the processes and as a platform for simulating scenarios and testing different strategies to reduce the risk of zoonotic spread."</p><h2 id="info2" data-magellan-target="info2">Starting to achieve results</h2><p>The Ume&aring; group has been involved from the beginning and participated in the work of designing the application for funding from Horizon Europe. The project has been in the upstart phase, but now the researchers are starting to see concrete results. Among other things, they have identified several interesting research tracks that they are now delving into.</p><p>"For example, we investigate how socio-ecological factors affect the distribution of important host species in relation to anthropogenic activities within tropical regions, how stress levels in ecosystems and species can increase the risk of pathogens, as well as how viral properties develop evolutionarily to enable spread between species - including to humans. At the same time, we look forward to the next project phase, where we expect more and clearer results."</p><h2 id="info3" data-magellan-target="info3">Collaboration requires communication</h2><p>Collaboration is essential in a multidisciplinary project like this. It requires good coordination, open communication and a willingness to learn from each other.</p><p>"It is incredibly inspiring to work together with experts from different fields and combine our knowledge to reach common goals. We hope that the research within the project with joint efforts can contribute with concrete tools and guidelines to identify and prevent future potential pandemics."</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/sjodin_henrik_0569_200131_mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/sjodin_henrik_0569_200131_mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/sjodin_henrik_0569_200131_mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/sjodin_henrik_0569_200131_mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/sjodin_henrik_0569_200131_mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/bc87fc687d5e4c148befa85d5d1bf4d1/sjodin_henrik_0569_200131_mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Henrik Sj&ouml;din has a background in ecology and theoretical ecology. Several of the processes within infection research, the project and especially within one-health have clear ecological aspects. It is about how pathogens, such as viruses or malaria parasites, interact with their environment, to how socio-ecological systems work &ndash; including the interaction between wild hosts, disease vectors (such as mosquitoes), humans and human activities.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div>/en/news/understanding-the-spread-of-animal-infections--prevent-the-next-pandemic_12017600//en/news/eu-invests-68-million-in-umea-researchers_12014634/How can we fight deadly viruses, turn nuclear waste into valuable resources, and create almost limitless digital storage? These are just a few of the challenges Umeå University researchers have received EU funding to tackle.Thu, 12 Dec 2024 11:22:24 +0100<p>Looking at the outcomes of the 2023 funding calls, 20 research projects at Ume&aring; University will share nearly &euro;5.9 million (around SEK 68 million) in support from various EU research programmes. These projects address some of the most urgent issues of our time, including sustainability, health, technological innovation, and societal security.</p><p>EU funding gives researchers at Ume&aring; University the opportunity to advance their pioneering work, develop innovative solutions, and collaborate with leading organisations across Europe and globally.</p><h2 id="info0" data-magellan-target="info0">Interested in the projects?</h2><p>Click on the expandable headings below to discover more about the research and the specific goals our researchers are working towards.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/ccbbaf29109b4007833291cc362108fe/kamenos_nick_5124_220518_sjn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ccbbaf29109b4007833291cc362108fe/kamenos_nick_5124_220518_sjn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ccbbaf29109b4007833291cc362108fe/kamenos_nick_5124_220518_sjn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ccbbaf29109b4007833291cc362108fe/kamenos_nick_5124_220518_sjn3.jpg?mode=crop&amp;width=640 640w, /contentassets/ccbbaf29109b4007833291cc362108fe/kamenos_nick_5124_220518_sjn3.jpg?mode=crop&amp;width=854 854w, /contentassets/ccbbaf29109b4007833291cc362108fe/kamenos_nick_5124_220518_sjn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Nicholas Kamenos, professor at the Department of Ecology and Environmental Science, is one of the Ume&aring; University researchers awarded EU funding. His research focuses on collaborations aimed at better equipping us to face climate change and improve the management of the world&rsquo;s water resources.</p><span class="bildPhotografer"><span class="photo">Image</span>Simon J&ouml;nsson, Inhousebyr&aring;n</span></div></div><p>&nbsp;</p><h2 id="info1" data-magellan-target="info1">HORIZON EUROPE</h2><h2 id="info2" data-magellan-target="info2">Scientific Excellence<br><br></h2><h3>European Research Council (ERC) &ndash; Starting Grant</h3><p class="foldable">MagneticTWIST: Twisted light could revolutionise data storage</p><p><strong>For decades, magnetism has been the cornerstone of data storage, from cassette tapes to hard drives. Researcher Nicol&ograve; Maccaferri is now testing an innovative idea that could, in theory, offer us virtually limitless storage capacity.</strong></p><p>He is investigating a phenomenon known as 'twisted light' &ndash; light that not only moves forward but also spins around its axis, much like the way Earth rotates on its axis while orbiting the Sun.</p><p>As light is a form of electromagnetic radiation, it can influence the magnetism in hard drives. By directing short pulses of twisted light with extreme precision at the nanometre (one billionth of a metre) scale, it may be possible to manipulate magnetism in new ways never considered. This breakthrough could enable vast amounts of data to be stored on tiny surfaces, all while maintaining speed and efficiency.</p><p>Maccaferri has received research funding to explore this idea and demonstrate that it is indeed possible to control magnetism with twisted light. If successful, this technology could transform data storage and processing, with significant potential for applied research fields such as cryptography, artificial intelligence, and quantum technologies.</p><p><a href="~/link/6d85dab80f72466f86b1d24a8dcc5847.aspx" target="_blank" rel="noopener"> Nicol&ograve; Maccaferri</a>, assistant professor at the Department of Physics, has received just over 2 million euros for the project.&nbsp;</p><h3>Marie Skłodowska-Curie Actions &ndash; Postdoctoral Fellowships</h3><p class="foldable">EnteroInfection: One step closer to stopping viruses</p><p><strong>Enteroviruses, like polioviruses, do more than infect cells &ndash; they transform them into "virus factories." Researchers are uncovering how these viruses hijack cellular structures to replicate, bringing us closer to discovering ways to stop them.</strong></p><p>The project EnteroInfection focuses on how enteroviruses exploit autophagy &ndash; the cell&rsquo;s recycling process &ndash; to create an environment conducive to viral replication. A key player in this process is the viral protein 2C, which assembles virus components at the right location within the cell.</p><p>Researchers have found that autophagosomes, cellular structures usually responsible for cleanup, are instead repurposed to house proteins crucial for the virus&rsquo;s strategy. By integrating insights from cell biology, biochemistry, and structural biology, the team seeks to map how these proteins contribute to viral replication.</p><p>Using tools like cryo-electron microscopy and mass spectrometry, the researchers aim to uncover methods to block viral infections. Their findings could pave the way for new treatments for virus-related diseases.</p><p>Postdoctoral fellow <a href="~/link/72a62eb8c42a4b759a48da25e9a7c9bd.aspx" target="_blank" rel="noopener">Marie Sorin</a> and research leader <a href="~/link/516fa112a87b429188cd28ea9d945b03.aspx" target="_blank" rel="noopener">Lars-Anders Carlson</a> at the Department of Medical Chemistry and Biophysics have received nearly 207,000 euros for the project.</p><p class="foldable">EBOVmembrinteract: Advancing treatments for deadly viruses</p><p><strong>Filoviruses, including Ebola, rank among the deadliest pathogens, with emerging species posing increasing risks. Researchers are exploring how these viruses invade our cells and why some are more dangerous, aiming to develop effective treatments.</strong></p><p>The EBOVmembrinteract project focuses on the virus&rsquo;s surface glycoproteins &ndash; proteins essential for attaching to and entering host cells. These glycoproteins are decorated with specific viral carbohydrates that seem to influence how efficiently the virus spreads.</p><p>Using advanced techniques like mass spectrometry and biophysical analysis, researchers are investigating how these carbohydrates affect the virus's ability to enter and exit host cells. Understanding these mechanisms could help identify ways to block infection, paving the way for new treatments.</p><p>The project&rsquo;s findings have the potential to significantly enhance global efforts to combat these deadly viruses and bolster preparedness for future outbreaks.</p><p>Postdoctoral fellow <a href="~/link/64e9baccdb0546a894dbf346220a702d.aspx" target="_blank" rel="noopener">Malgorzata Graul</a> and research leader <a href="~/link/1c0a359d7b484a57887181ad3ee98fab.aspx" target="_blank" rel="noopener">Marta Bally</a> at the Department of Clinical Microbiology have received nearly 207,000 euros for the project.</p><p class="foldable">CryoARC: Mapping virus factories to develop new treatments</p><p><strong>Alphaviruses, transmitted by mosquitoes in tropical regions, cause severe diseases in humans. In the CryoARC project, researchers are exploring how these viruses create small &ldquo;factories&rdquo; on the surface of cells to replicate and spread infection.</strong></p><p>The virus forms tiny spherical structures, known as spherules, where it rapidly multiplies. By mapping how these factories are built and how they function, the researchers aim to develop new drugs that block the virus&rsquo;s replication, offering protection against these diseases.</p><p>A central tool in this research is cryo-electron microscopy, which allows scientists to study the virus at the nanoscale. By uncovering which components of the cell&rsquo;s machinery the virus exploits to build its factories, the team hopes to identify ways to disrupt its spread.</p><p>The CryoARC project could become an important step forward in combating diseases caused by alphaviruses, providing new tools to protect people in vulnerable regions.</p><p>Postdoctoral fellow Dinesh Dhurvas Chandrasekaran and research leader <a href="~/link/516fa112a87b429188cd28ea9d945b03.aspx" target="_blank" rel="noopener">Lars-Anders Carlson</a> at the Department of Medical Biochemistry and Biophysics have received just over 222,000 euros for the project.</p><p class="foldable">MitoDNASen: Towards healthier ageing</p><p><strong>Could mitochondria hold the secret to healthier ageing? Researchers in the MitoDNASen project are diving into these vital parts of our cells to find ways to combat age-related diseases and harmful inflammation.</strong></p><p>When our cells face stress, such as DNA damage or shortened telomeres, they can enter a state where they stop dividing. This process, called senescence, is a natural defence mechanism that prevents the development or spread of cancer. However, as senescent cells accumulate in the body, they can trigger inflammation and contribute to conditions like arthritis, cardiovascular diseases, and cancer.</p><p>The MitoDNASen project investigates how mitochondrial DNA changes during this process. The researchers have found that mitochondria play a much larger role than previously understood in driving the inflammatory responses linked to these diseases. By unravelling how mitochondrial DNA is affected during senescence, they hope to develop new treatments that mitigate the negative effects of these cells and promote better health in older individuals.</p><p>The project holds the potential to become a key piece in alleviating diseases caused by cellular ageing, ultimately improving the quality of life for many.</p><p>Postdoctoral fellow <a href="~/link/3b2fafef2d7d471194bea369ed694e92.aspx" target="_blank" rel="noopener"> Valentin L'H&ocirc;te</a> and research leader <a href="~/link/29452e085fb743ef84fb904db7e09944.aspx" target="_blank" rel="noopener">Sjoerd Wanrooij</a> at the Department of Medical Biochemistry and Biophysics have received nearly 207,000 euros for the project.</p><p class="foldable">ATOPS: Using light and magnetism to revolutionise electronics</p><p><strong>What if magnetism could be controlled by light at unprecedented speeds? Researchers at Ume&aring; University are pursuing this groundbreaking idea, with the potential to unlock faster, more energy-efficient technologies.</strong></p><p>The ATOPS project investigates how ultrafast light pulses, lasting just a few femtoseconds (one quadrillionth of a second), can influence magnetic properties. The aim is to create faster and more precise electronic devices by using light to manipulate magnetism.</p><p>The researchers are focusing on MnPd2, a material with unique electronic and magnetic properties that can be controlled with light. They believe it has the potential to accelerate data storage and improve information processing efficiency.</p><p>Using advanced optical methods, the team hopes to demonstrate how MnPd2 can enable ultrafast magnetic control. If successful, their work could pave the way for next-generation technologies, including quantum computing.</p><p>Postdoctoral fellow <a href="~/link/0ea2755dfb0c4c1b83b40040274d0298.aspx" target="_blank" rel="noopener">Lakshmi Das</a> and research leader <a href="~/link/6d85dab80f72466f86b1d24a8dcc5847.aspx" target="_blank" rel="noopener">Nicol&ograve; Maccaferri</a> at the Department of Physics have received nearly 207,000 euros for the project.</p><p class="foldable">UNID: One light source to transform multiple industries</p><p><strong>Imagine a lighting solution that is sustainable, cost-effective to produce, recyclable, and versatile enough to be used in healthcare, packaging, architecture, and fashion. Too good to be true? Light-emitting electrochemical cells (LECs) could make it a reality.</strong></p><p>LEC technology relies on a simple layer of organic materials mixed with electrolytes, enabling the creation of thin, flexible, and biodegradable light sources that emit a soft glow. However, LECs have faced challenges, including short lifespans and low efficiency. This is due to the ions that power the light also degrading the organic material.</p><p>Researchers in the UNID project are working intensively to understand and control this process, aiming to extend the lifespan and improve the efficiency of LEC lighting. If successful, this groundbreaking technology could offer not just a sustainable light source but also transform multiple industries by making lighting both eco-friendly and cost-efficient.</p><p>Postdoctoral fellow <a href="~/link/0ce03f4a681e4f598c1e24ab87a2802b.aspx" target="_blank" rel="noopener">Anton Kirch</a> and research leader <a href="~/link/6fb653224d8b4dc9b1f903f2945a1183.aspx" target="_blank" rel="noopener">Ludvig Edman</a> at the Department of Physics have received just over 222,000 euros for the project.</p><h3>Marie Skłodowska-Curie Actions &ndash; Doctoral Networks</h3><p class="foldable">ENDAMR: Fighting antibiotic resistance</p><p><strong>Antibiotic resistance is one of the most pressing global health threats, contributing to millions of deaths each year. The ENDAMR project is empowering young researchers with the tools and knowledge to better understand and tackle the rise of resistance &ndash; an effort that could ultimately save lives.</strong></p><p>As part of the EU Doctoral Networks, ENDAMR provides PhD students with the opportunity to participate in international, interdisciplinary research. Participants not only contribute new insights into antibiotic resistance, but also gain skills for future careers in both academia and industry, with a focus on entrepreneurship, teaching, and science communication.</p><p>The research within ENDAMR spans several key areas. One team is investigating how antibiotic resistance affects bacteria in the gut microbiome and exploring microbiome-based treatments to help control infections. Another team is mapping the spread of resistance between bacteria, examining the genetic and environmental factors at play. Additionally, researchers are studying mechanisms such as tolerance and heteroresistance, aiming to develop more effective diagnostic tools and treatment strategies. The project also explores the potential of antibiotic combinations to improve patient care and reduce the risk of resistance.</p><p>The ENDAMR project is training a new generation of researchers who are committed to developing innovative solutions to combat antibiotic resistance &ndash; today and for the future.</p><p><a href="~/link/faa3434db59e461ea19ee62305e8468f.aspx" target="_blank" rel="noopener">Andre Mateus</a> at the Department of Chemistry has received nearly 294,000 euros for his part of the project.</p><h3>Marie Skłodowska-Curie Actions &ndash; MSCA and Citizens</h3><p class="foldable">ForskarFredag: A chance to explore the world of science</p><p><strong>What does a scientist actually do? How does research shape our daily lives? During ForskarFredag, Sweden&rsquo;s largest science festival, the public gets to meet researchers, participate in exciting experiments, and discover why science matters for society.</strong></p><p>Held annually across the country and online, ForskarFredag invites people of all ages to explore science under the motto: "Researchers are ordinary people with extraordinary jobs." From debates and science shows to hands-on experiments, the festival offers something for everyone. Children and young people can even "borrow a researcher" for their classrooms or join real citizen science projects.</p><p>As part of the EU&rsquo;s European Researchers&rsquo; Night, the festival shines a spotlight on how research helps tackle global challenges. This year&rsquo;s theme focuses on sustainable development and future technologies, with activities developed in collaboration with research projects from across Europe.</p><p>ForskarFredag is coordinated by the non-profit association Vetenskap &amp; Allm&auml;nhet, which has been connecting organisers nationwide since 2006 to create an inspiring and educational celebration of science for all ages.</p><p><a href="~/link/7e966bc84b3147e98c92fe6a682befd6.aspx" target="_blank" rel="noopener">Gabrielle Beans Pic&oacute;n</a>, staff scientist at Curiosum, has received nearly 15,000 euros for her contribution to this initiative.</p><h3>Research infrastructures</h3><p class="foldable">Infra4NextGen: Gathering data and young voices for a better Europe</p><p><strong>The Infra4NextGen project aims to make it easier for policymakers to access and use social science data. By bringing together information scattered across national registries, the project seeks to support a stronger, more sustainable Europe in the wake of the pandemic.</strong></p><p>The Next Generation EU recovery fund is all about building a better future &ndash; greener, more digital, healthier, fairer, and more resilient. But achieving these goals requires reliable data that is easy to interpret and use. This is where Infra4NextGen steps in.</p><p>Led by the European Social Survey (ESS), the project brings together top social science institutions to collect, harmonise, and share data. This information will be accessible to policymakers, analysts, and even the public. Interactive tools and training materials will also be created to make the data as useful as possible.</p><p>A special focus is on Europe&rsquo;s youth. Their voices will help shape discussions around the EU&rsquo;s priorities, ensuring young people&rsquo;s perspectives are part of the decision-making process for a more inclusive future.</p><p><a href="~/link/c17837c3cd1c4dd7be9c757ce798cca3.aspx" target="_blank" rel="noopener">Mikael Hjerm</a>, professor at the Department of Sociology and Swedish coordinator for the European Social Survey, has received just over 105,000 euros for his part in the project.</p><p class="foldable">AQUASERV: Pooling resources for a sustainable blue economy</p><p><strong>Our waters are vital to life and livelihoods, but protecting them requires a collective effort. The AquaServ project is creating a network that allows researchers and businesses across the EU to share tools, facilities, and expertise to study and improve sustainable water management.</strong></p><p>This initiative will provide access to cutting-edge resources &ndash; from lab equipment to expert advice &ndash; for those working on freshwater and marine ecosystems. Whether online or on-site, these resources will help accelerate discoveries and solutions for managing our seas and lakes sustainably.</p><p>Beyond research, AquaServ is focused on ensuring a lasting impact. Networking, training programmes, and outreach activities will ensure that the project&rsquo;s benefits extend well beyond its funding period, empowering not only researchers but also policymakers and technical teams.</p><p><a href="~/link/1c54b05d535a47f1be96058a78c51334.aspx" target="_blank" rel="noopener">Nicholas Kamenos</a>, professor at the Department of Ecology and Environmental Science, has received just over 272,000 euros for his part of the project.&nbsp;</p><p class="foldable">IRISCC: Joining forces to tackle climate change</p><p><strong>Climate change is one of the most urgent challenges of our time. Addressing it requires a deep understanding of the complex factors at play &ndash; from extreme weather events to social and economic impacts. This is where IRISCC aims to make a difference.</strong></p><p>IRISCC is an EU initiative that unites leading research infrastructures from diverse scientific fields to create a shared platform. This platform will enable researchers, policymakers, and other stakeholders to exchange data and resources, driving sustainable solutions to climate challenges.</p><p>The project will develop a comprehensive catalogue of research resources, including a collaborative lab for transdisciplinary studies and demonstrators showcasing the benefits of integrated approaches. IRISCC will also offer targeted services for policymakers and risk management professionals.</p><p>The goal is to accelerate research, make resources accessible to all, and support faster, more effective action against climate change. All data will be openly available and aligned with FAIR principles to benefit both research and policymaking.</p><p><a href="~/link/1c54b05d535a47f1be96058a78c51334.aspx" target="_blank" rel="noopener">Nicholas Kamenos</a>, professor at the Department of Ecology and Environmental Science, has received just over 113,000 euros for his part of the project.&nbsp;</p><h2 id="info3" data-magellan-target="info3">Global Challenges and European Industrial Competitiveness<br><br></h2><h3>Cluster 1: Health</h3><p class="foldable">NEMESIS: Protecting against hormone-disrupting chemicals</p><p><strong> Certain chemicals in the environment can disrupt metabolism and increase the risk of diseases such as obesity and type 2 diabetes. The Nemesis project aims to develop new insights and practical tools to understand and counter these risks.</strong></p><p>Endocrine-disrupting chemicals (EDCs), found in products ranging from plastics to cosmetics, can interfere with essential bodily functions. Studies show these chemicals affect organs like the liver and pancreas, contributing to conditions such as atherosclerosis and diabetes. Exposure during critical early life stages can be especially harmful, with potential effects passed on to future generations.</p><p>The Nemesis project brings together experts from diverse research fields to investigate how EDCs impact human health. Researchers will explore whether these chemicals alter gut bacteria composition, which can influence metabolism, and develop biomarkers for early detection. The project will also create new testing methods to reduce reliance on animal studies.</p><p>By involving the public and key societal stakeholders, Nemesis aims to ensure that the research findings inform future decisions on chemical management, ultimately protecting health and reducing the risks associated with harmful chemicals in our environment.</p><p><a href="~/link/84d5d1bf2f1347ac9bada1a53dccec48.aspx" target="_blank" rel="noopener">Sophia Harlid</a>, docent at the Department of Diagnostics and Intervention, and <a href="~/link/d37c9f9f78844576951856007aa294c3.aspx" target="_blank" rel="noopener">Marie-Therese Vinnars</a>, assistant professor at the Department of Clinical Sciences, have received just over 212,000 euros for their part of the project.</p><h3>Cluster 4:&nbsp;Digital, Industry and Space</h3><p class="foldable">ELECTRA: Electrification could make cement production fossil-free</p><p><strong>Cement and lime are essential building materials, but their production is a major source of global CO₂ emissions. The Electra project explores whether electric heating could replace fossil fuels in the process, potentially cutting emissions to near zero.</strong></p><p>Instead of burning fuel to heat limestone to the necessary temperature of up to 2,000 degrees Celsius, Electra aims to use electricity from renewable energy sources. This shift could enable fossil-free production of cement and lime. The technique, currently under development and upscaling, is flexible enough to suit both new factories and retrofitted older facilities. Researchers estimate it could eliminate fuel-based emissions entirely in these industries, cutting total carbon dioxide emissions by more than 90 percent.</p><p>Given cement&rsquo;s global importance as a construction material, this innovation could significantly lower the industry&rsquo;s carbon footprint. Electra is also accelerating the transition to electric-powered production through scalable platform solutions designed for rapid implementation.</p><p>If successful, the project could revolutionise cement and lime manufacturing, bringing us closer to a fossil-free future.</p><p><a href="~/link/61c32be3ebc749be9cd649259dbbdfc1.aspx" target="_blank" rel="noopener">Markus Brostr&ouml;m</a>, professor at the Department of Applied Physics and Electronics, has received just over 201,000 euros for his part of the project.</p><h3>Cluster 6: Food, Bioeconomy, Natural Resources, Agriculture and Environment</h3><p class="foldable">ILLUQ: Addressing the threats from thawing permafrost in the Arctic</p><p><strong>The rapid thawing of permafrost due to climate change is releasing harmful substances that pose a significant threat to both people and infrastructure in the Arctic. The interdisciplinary Illuq project seeks long-term solutions to mitigate these risks.</strong></p><p>Currently, permafrost covers over a fifth of the Northern Hemisphere&rsquo;s landmass. As it thaws, large amounts of organic material and hazardous substances, including heavy metals and microorganisms, are released. This creates serious risks for both human and animal life, as well as local infrastructure, with far-reaching consequences for public health, the economy, and society.</p><p>While these challenges are well-recognised, they have often been studied in isolation, resulting in solutions that fail to address the full scope of the issue. The Illuq project takes a holistic approach, bringing together researchers and local communities to develop effective tools and knowledge to tackle future Arctic challenges.</p><p>The project aims to deliver concrete results for managing the risks associated with thawing permafrost, including its impact on health, pollution, and infrastructure &ndash; and contribute to a more sustainable future in a rapidly changing world.</p><p><a href="~/link/78dc524dac6e4e67a10673fb3f073101.aspx" target="_blank" rel="noopener"> Matthias Siewert</a>, associate professor at the Department of Ecology and Environmental Science, has received just over 330 000 euros for his part of the project.</p><h3>European Partnerships</h3><p class="foldable">The META Trial: Hoping to prevent diabetes in people living with HIV</p><p><strong>People living with HIV are at a higher risk of developing diabetes. In Tanzania, researchers are studying whether metformin, a medication for type 2 diabetes, can prevent or delay diabetes in this group.</strong></p><p>Launched in October 2021 in Dar es Salaam, the study is a randomised, placebo-controlled trial in people on antiretroviral therapy with pre-diabetes. Participants are being followed for three years to evaluate whether metformin reduces the risk of diabetes in this high-risk group.</p><p>The study is a collaboration between Tanzanian and European researchers, conducted in close partnership with Tanzanian health authorities.</p><p>The project aims to determine metformin&rsquo;s effectiveness and cost-effectiveness, while also generating valuable knowledge to inform future health policies and manage the dual challenges of diabetes and HIV in Africa.</p><p><a href="~/link/20fa79b0f27649c99d3cf9c285e26364.aspx" target="_blank" rel="noopener"> Anni-Maria Pulkki-Br&auml;nnstr&ouml;m</a>, associate professor at the Department of Epidemiology and Global Health, has received nearly 76,000 euros for her part of the project.</p><h3>Widening Participation and Spreading Excellence</h3><p class="foldable">WIDE AcrossEU: Collaboration to strengthen research capacity across the EU</p><p><strong>Through the WIDE AcrossEU project, researchers in the Czech Republic, North Macedonia, and Ukraine are receiving support from Sweden and Finland to build capacity and foster networking. The goal is to improve their chances of participating in the EU&rsquo;s largest research programmes.</strong></p><p>Spanning 40 months, the project focuses on enhancing skills and creating new opportunities for researchers in "widening countries" &ndash; nations that have historically had lower participation in EU research programmes.</p><p>By mapping the researchers' needs and offering training and networking opportunities, the project aims to increase their ability to engage in EU-funded projects. It also seeks to help these countries better utilise the research and infrastructure already funded through regional EU programmes like ERDF and Interreg.</p><p>In the long term, WIDE AcrossEU hopes to contribute to a more equal and inclusive research environment in Europe, where more people can both contribute to and benefit from EU collaborations in research and innovation.</p><p><a href="~/link/ba62272c8d2c4885ad0805d3382ad56b.aspx" target="_blank" rel="noopener"> Agneta H. Plamboeck</a>, EU expert at the Research Support and Collaboration Office, has received nearly 135,000 euros for her part in the project.</p><h3>Euratom Research and Training Programme</h3><p class="foldable">MaLaR: New method turns nuclear waste into a resource</p><p><strong>Nuclear waste poses a significant environmental challenge, but the Malar project is pioneering a sustainable solution. Researchers aim to develop a method that manages nuclear waste while recycling valuable metals &ndash; a breakthrough in resource management.</strong></p><p>The project focuses on lanthanides, rare earth metals vital for technologies like mobile phones, electric vehicles, and wind turbines. Traditional methods of extracting these metals from nuclear waste are costly and inefficient. By utilising innovative 3D structures made from 2D materials, the project seeks to revolutionise the process, making it more efficient and eco-friendly.</p><p>This innovation simplifies the separation of lanthanides from nuclear waste, enhancing waste management and enabling the recycling of valuable metals. The project brings together leading European institutions, including Ume&aring; University, known for its expertise in material design.</p><p>With its cutting-edge approach, the Malar project addresses the dual challenge of nuclear waste and sustainable materials, paving the way for a greener, resource-efficient future.</p><p><a href="~/link/e5bfd959cf0447518516facc70f06a65.aspx" target="_blank" rel="noopener">Alexandr Talyzin</a>, professor at the Department of Physics, has received nearly 567,000 euros for his part of the project.</p><h2 id="info4" data-magellan-target="info4">ERASMUS+</h2><p class="foldable">CriticalMaking: Fighting digital misinformation through hands-on teaching</p><p><strong>In a world where misinformation spreads quickly online, educators need practical tools to help their students separate fact from fiction. The&nbsp;CriticalMaking&nbsp;project is giving teachers the skills and confidence to do just that.</strong></p><p>Through creative 'makerspaces' &ndash; hands-on learning environments &ndash; educators in science, technology, engineering, and maths will explore real-world scenarios and learn how to use experiments to counter false information. This practical approach equips teachers with tools to fight misinformation not just through arguments but through demonstrations, inspiring their students to think critically about the information they encounter online.</p><p>Part of the&nbsp;EU Digital Education Action Plan, CriticalMaking is also about building a sustainable future. The project will develop teaching materials and training programmes for teachers and policymakers, helping Europe&rsquo;s educators prepare the next generation for the digital age.</p><p><a href="~/link/15c6c555ca8e401280f3c537a5cc19a9.aspx" target="_blank" rel="noopener"> Madelen Bodin</a>, associate professor at the Department of Science and Mathematics Education and director of Curiosum, has received nearly 215,000 euros for her part in the project.</p><p class="foldable">Good Game: Promoting better mental health in esports</p><p><strong>While esports offer exciting opportunities, they also present significant mental health challenges. The Good Game project aims to combat these issues by developing and implementing targeted interventions across Europe.</strong></p><p>Esports, where individuals or teams compete in popular video games, has grown rapidly, attracting players of all levels. However, research highlights that the pressure, long training hours, and competitive environment can negatively impact players&rsquo; mental well-being. As such, new tools and strategies are needed to support mental health within esports.</p><p>The Good Game project will develop an online-based psychoeducational intervention, combining psychological education with practical tools. The programme targets both amateur and professional players and consists of modules focused on emotion management, sleep improvement, mental training, and coaching for players, coaches, and parents.</p><p>The goal is to provide players and their support networks with the tools to manage the psychological challenges of esports, fostering a more sustainable and positive future for everyone involved in this rapidly growing field.</p><p>Michael Trotter at the Department of Psychology has received nearly 30,000 euros for his part in the project.</p>/en/news/eu-invests-68-million-in-umea-researchers_12014634//en/news/umea-university-climbs-in-global-sustainability-ranking_12014614/All faculty staff and students are invited to nominate candidates for the Faculty of Medicine's Distinguished Teaching Award 2025. Nominations must be received no later than February 28th.Tue, 10 Dec 2024 11:59:07 +0100<p>The award aims to encourage teachers to make good pedagogical contributions in first-cycle and second-cycle education. The award may be presented to an individual teacher or to several teachers. Teachers are defined as professors, associate professors, lecturers, research assistants, part-time fixed-term teachers and guest teachers.</p><p>The award winner(s) will have made a well-documented pedagogical contribution and demonstrated excellence in the following areas:</p><ul><li>pedagogical development work</li><li>interaction with students</li><li>collaboration with colleagues</li></ul><p>Decisions on award winner(s) are made by an evaluation committee consisting of the chair and a teacher representative from the Strategic Board for Education, a teacher representative appointed by the Faculty Board and a student representative from the Ume&aring; Medical and Health Sciences Students' Union. The committee will take gender equality into account when evaluating the nominations.</p><p>Award amount: SEK 50,000</p><p>Nomination: <a title="Nominate" href="https://forms.office.com/pages/responsepage.aspx?id=-aZLWjH1Mk-UZzmPGead5JIzmxwFahFDvBuEHp8TC1JUOTFRRkQ3VjBXOUpaUkpaRU5GNldMOE81Ri4u&amp;route=shorturl" target="_blank" rel="noopener">Link to nomination</a></p>/en/news/distinguished-teaching-award--nominate-candidates-for-the-award_12014580//en/news/combines-her-residency-position-with-research_12014093/Umeå University's international students are very satisfied with studying here. This is shown, among other things, by the International Student Barometer survey, where Umeå ranks high in the following categories: living, support, and overall satisfaction. Now, the university aims to increase the number of international students even further, with a particular focus on students from the EU/Europe.Mon, 02 Dec 2024 10:19:13 +0100<p>&nbsp;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/6b586d289ce9400a968526d67b61715a/madrid_13.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/6b586d289ce9400a968526d67b61715a/madrid_13.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/6b586d289ce9400a968526d67b61715a/madrid_13.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/6b586d289ce9400a968526d67b61715a/madrid_13.jpg?mode=crop&amp;width=640 640w, /contentassets/6b586d289ce9400a968526d67b61715a/madrid_13.jpg?mode=crop&amp;width=854 854w, /contentassets/6b586d289ce9400a968526d67b61715a/madrid_13.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Francine Ferretti Horst and Gabriel Quintanilla Madro&ntilde;al from Ume&aring; University at the recruitment fair FIEP in Madrid 18 November 2024.</p><span class="bildPhotografer"><span class="photo">Image</span>Benedetta Mascalchi</span></div></div><p>Francine Ferretti Horst works as a project coordinator at the International Office on a two-year project to attract more European students to Ume&aring; University.<br>&nbsp;<br>The initiative includes having a greater physical presence in Europe. Recently, Ume&aring; University participated in a student recruitment fair in Madrid. Soon, the university will head to Germany for recruitment fairs in Frankfurt, Berlin, and Hamburg. Fairs are also planned in February and March in Barcelona and Milan, as well as a return visit to Madrid. Other Swedish institutions such as Stockholm University, Chalmers, Link&ouml;ping University, and J&ouml;nk&ouml;ping University also participate in these recruitment fairs.<br>&nbsp;<br>"The advantage of being present at a fair is meeting students face-to-face. It's also good to be visible where other institutions are. It puts Ume&aring; University on the map in these new contexts. We try to bring an alumnus to each fair, i.e., a student who has previously studied at Ume&aring; University," says Francine Ferretti Horst.<br>&nbsp;<br>In Madrid in November, Gabriel Quintanilla Madro&ntilde;al from Madrid participated and shared his experiences of studying in Ume&aring;. Gabriel did an Erasmus exchange at Ume&aring; University in 2023.<br>&nbsp;<br>The students Francine and Gabriel met were interested in the university's programmes offered in English and were also very curious about life in Ume&aring;:<br>&nbsp;<br>"It's a fantastic experience to be part of the beginning of the students' journey. Going abroad to study a master's or bachelor's program is a big decision. We want to build a relationship with our prospective students and give them the support they need so that they feel they have made a well-thought-out choice when they choose Ume&aring; University," says Francine Ferretti Horst.</p><h3><br>Support throughout the whole journey</h3><p>Ume&aring; University wants to support students throughout their study journey; from the first meeting with a prospective student at, for example, a fair, through the application and admission process, to when the student is on-site and studying, and even later when the student graduates and enters the job market.<br>&nbsp;<br>"A holistic perspective is important for recruitment, retention, and intake. Therefore, the support functions we have at our university, such as general study guidance, programme guidance, student health, and support for students with disabilities, are extremely important. The importance of our buddy programme is also something that is often mentioned by our international students," says Francine Ferretti Horst.<br>&nbsp;<br>The International Office, in consultation with the university's faculties, has identified five EU countries to focus on within the project, with Spain, Germany, and Italy being three of them. The other countries are France and the Netherlands.<br><br>"We will focus on a physical presence in these countries, but that doesn't mean we exclude other European countries when we focus on student recruitment. We also participate in digital fairs, organize our own webinars, and conduct search engine advertising campaigns focusing on all countries within the EU, EEA, and Switzerland. There are also plans for more on-site events at embassies together with other Swedish institutions," she continues.<br>&nbsp;<br>Another part of the student recruitment initiative towards Europe is to collaborate with faculties, departments, and programmes to gather strengths around international student recruitment. In October, the International Office conducted a workshop together with the Faculty of Science and Technology to identify what efforts are currently being made at different levels and how to better collaborate to attract international students. The workshop was very appreciated. Now, a similar workshop is planned with the Faculty of Social Sciences. In the future, other faculties and units will also be contacted with a request for a similar workshop.<br><strong>&nbsp;<br></strong><br><strong>Recruitment fairs &ndash; autumn 2024 and spring 2025:</strong><br>18/11 Madrid<br>30/11 Frankfurt<br>4/12 Berlin<br>6/12 Hamburg<br>24/2 Madrid<br>27/2 Barcelona<br>3/2 Milan<br>&nbsp;<br><a title="recruitment fairs" href="~/link/44c682c48d174662a7bc5d9b81c11835.aspx">Read more about the recruitment fairs</a></p><p><a title="international student barometer" href="~/link/7f857e6321fc47cf90a6bfb01aba2a26.aspx">More about Ume&aring; University's results in the International Student Barometer</a></p>/en/news/umea-university-focuses-on-recruiting-students-from-europe_12010797//en/news/immune-system-dna-holds-key-for-multiple-disease-personalised-therapies_12010781/Some people naturally have higher levels of proteins that protect them from covid-19. New studies at Umeå University of our immune system may pave the way for more personalised treatments of both covid-19 and autoimmune disorders.Tue, 03 Dec 2024 08:59:33 +0100<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/8c2429a9167e4b0f9e4e6ac44b958363/ionut_sebastian_mihai2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/ionut_sebastian_mihai2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/ionut_sebastian_mihai2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/8c2429a9167e4b0f9e4e6ac44b958363/ionut_sebastian_mihai2.jpg?mode=crop&amp;width=640 640w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/ionut_sebastian_mihai2.jpg?mode=crop&amp;width=854 854w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/ionut_sebastian_mihai2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Ionut Sebastian Mihai, doctoral student at the Industrial Doctoral School at Ume&aring; University.</p><span class="bildPhotografer"><span class="photo">Image</span>Linda Pommer</span></div></div><p>In his doctoral research at Ume&aring; University and the Industrial Doctoral School, Ionut Sebastian Mihai has explored how our body's defense system works at the smallest level to find new ways to treat diseases like covid-19 and autoimmune disorders.</p><p>One of his findings involves natural proteins, called serpins, that can block the SARS-CoV-2 virus &ndash; the virus responsible for covid-19 &ndash; from entering human cells. Remarkably, some individuals naturally have higher levels of these proteins.</p><p>&ldquo;Think of these proteins as gatekeepers that keep the virus out. This discovery could lead to new treatments that enhance these gatekeeper mechanisms in other people,&rdquo; says Ionut Sebastian Mihai.</p><h2 id="info0" data-magellan-target="info0">Enhances natural defenses</h2><p>Serpins work by inhibiting a specific enzyme which the virus uses to enter cells. Individuals with higher levels of serpins in their lung cells may therefore have increased resistance to covid-19. This finding suggests potential avenues for developing treatments that enhance natural defenses against the virus.</p><p>Ionut Sebastian Mihai's research has also shed light on other critical components of the immune defense system, which is like a complex army with different types of soldiers, each playing a unique role in protecting us from illnesses. One of these soldiers is a special type of white blood cell that helps coordinate the body's response to threats, called T cells. Ionut Sebastian Mihai has identified important "commanders" within these white blood cells, directing how they grown and respond to infections.</p><p>&ldquo;Understanding these cells at the DNA and RNA levels can help us find ways to develop vaccines and medicines that can boost the immune system when it is weak or calm it down when it is overactive,&rdquo; says Ionut Sebastian Mihai.</p><h2 id="info1" data-magellan-target="info1">More effective treatments</h2><p>The new research results could lead to therapies tailored to each person's unique immune system, making treatments more effective with fewer side effects.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/8c2429a9167e4b0f9e4e6ac44b958363/sem_image_22.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/sem_image_22.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/sem_image_22.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/8c2429a9167e4b0f9e4e6ac44b958363/sem_image_22.jpg?mode=crop&amp;width=640 640w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/sem_image_22.jpg?mode=crop&amp;width=854 854w, /contentassets/8c2429a9167e4b0f9e4e6ac44b958363/sem_image_22.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Image taken in the lab of an active T cell.</p><span class="bildPhotografer"><span class="photo">Image</span>Ionut Sebastian Mihai</span></div></div><p>&ldquo;For people whose immune systems mistakenly attack their own bodies, for example, as seen in autoimmune diseases like multiple sclerosis or rheumatoid arthritis, this research offers hope for treatments that can correct these mistakes. Same goes for hard to deal infections and certain types of cancer. The secret is in the genes and the environment.&rdquo;</p><p>Ionut Sebastian Mihai has also studied how certain viruses spread in the brain and identified signals in the immune system that help these infections progress. These findings could contribute to methods for preventing or treating severe brain diseases caused by viruses.</p><p><em>Ionut Sebastian Mihai&rsquo;s doctoral project has been funded by the Industrial Doctoral School at Ume&aring; University and Sartorius Stedim Data Analytics.</em></p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="11385cae-8252-405e-ab51-c6c6b5b782db" data-contentname="About the doctoral thesis">{}</div><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="74b92039-6a80-4930-ba4f-6ad48cdf6752" data-contentname="Fakta Företagsforskarskolan ENG (standard)">{}</div>/en/news/immune-system-dna-holds-key-for-multiple-disease-personalised-therapies_12010781//en/news/new-microscope-will-reveal-3d-cell-structures-at-nanoscales_12010819/Umeå Centre for Electron Microscopy (UCEM) recently inaugurated an advanced microscope which will contribute greatly to research in several life science fields. The new instrument is a FIB-SEM (Focused Ion Beam – Scanning Electron Microscope), specifically designed to reveal thin layers of cells whilst operating at extremely low temperatures, enabling detailed studies of biological samples at the nanoscale.Wed, 04 Dec 2024 09:33:54 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning24.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning24.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning24.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning24.jpg?mode=crop&amp;width=640 640w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning24.jpg?mode=crop&amp;width=854 854w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning24.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Erin Schexnaydre, staff scientists at UCEM, shows the new FIB-SEM instrument "Aquilos 2". The microscope can image biological samples at nanoscales, whilst the sample is kept at freezin -180 degrees Celsius.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><h2 id="info0" data-magellan-target="info0">Operating at -180&deg;C&nbsp;</h2><p>Here in Ume&aring;, we are used to freezing conditions, but in the labs at Ume&aring; Centre for Electron Microscopy (UCEM), they take the cold one step further. &nbsp;<br>&nbsp;&ldquo;Having cells frozen to very low temperatures preserve the biological structures within them, such as proteins, and allows us to study the functions of these proteins&rdquo;, explains Erin Schexnaydre, staff scientist at UCEM, who will be the manager of the new instrument, named Aquilos 2. &nbsp;<br>&nbsp;<br>Before the microscope is put to use, samples are frozen to below -180 &deg;C. This is done in a&nbsp;rapid cooling process, preventing ice crystals from forming in the sample which would otherwise cause damage to the sensitive biological structures.&nbsp;<br><br>&ldquo;However, the sample is at this stage too thick to be directly imaged by an electron microscope," says Erin Schexnaydre, &ldquo;which is why we need the combination of both the focused ion beam and the electron microscope.&rdquo;&nbsp;</p><p>By using a beam of charged particles &ndash; ions, Aquilos 2 can create thin layers of frozen samples &ndash; called cryo-lamella. Cryo-lamella can be as thin as 200 nanometers, which is 500 times thinner than human hair, and much thinner than the average size of a human cell. This technique opens the cell for detailed studies of its inner structures in 3D and is ideal for obtaining detailed images of the interior of cells.</p><h2 id="info1" data-magellan-target="info1">Round-the-clock science&nbsp;</h2><p>Although purchase was finalised already at the end of last year, it has been a long wait for the new microscope to be up and running. Following some necessary room reconfigurations, the instrument is now in use and was celebrated with a cheerful inauguration at UCEM and a contest of the best electron microscope image.&nbsp;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning13.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning13.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning13.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning13.jpg?mode=crop&amp;width=640 640w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning13.jpg?mode=crop&amp;width=854 854w, /contentassets/2dc289fc3d224c2abf5b3d3fe5347f3a/aquilos2_invigning13.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Cheerful mood at UCEM as the new FIB-SEM microscope "Aquilos 2" was inaugurated in November. It was celebrated with drinks and a competition of the best electron microscopy image.</p><span class="bildPhotografer"><span class="photo">Image</span>Anna Shevtsova</span></div></div><p>&ldquo;Aquilos 2 is designed to use the ion-beam overnight, which increases the throughput of cryo-lamella production and thus the collection of data,&rdquo; says Erin Schexnaydre. Obtaining more data quicker allows the researchers to explore complex biological structures more efficiently, opening doors to new scientific discoveries.&nbsp;<br><br>Who has access to the new microscope? &ldquo;Anyone at Ume&aring; University, or collaborators in SciLifeLab, who have projects requiring this microscope can be trained by the UCEM staff to use the new instrument,&rdquo; says Erin Schexnaydre, who hopes it will come in good use for many exciting research projects.</p>/en/news/new-microscope-will-reveal-3d-cell-structures-at-nanoscales_12010819//en/news/peter-skold-appointed-chair-of-the-european-polar-board_12009801/Umeå University is strengthening its Arctic profile. Professor Peter Sköld, former Director of the Arctic Centre and now an advisor to the Vice-Chancellor on Arctic affairs, has been elected Chair of the European Polar Board (EPB), an independent organisation that drives strategic priorities in the Arctic and Antarctic. Starting on January 1, 2025, the EPB Secretariat will be based at Umeå University. Thu, 28 Nov 2024 14:27:49 +0100<p>Peter Sk&ouml;ld has been an important figure at the EPB since 2018, initially serving as a delegate alongside Deputy Vice-Chancellor Dieter M&uuml;ller and since 2020 as a member of the Executive Committee. During his time on the committee, he has focused on integrating social science and humanities perspectives into the organisation&rsquo;s work.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/d96fc1ee79e947f2b3717dfc6de40008/skold_peter_2840_210914_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/d96fc1ee79e947f2b3717dfc6de40008/skold_peter_2840_210914_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/d96fc1ee79e947f2b3717dfc6de40008/skold_peter_2840_210914_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/d96fc1ee79e947f2b3717dfc6de40008/skold_peter_2840_210914_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/d96fc1ee79e947f2b3717dfc6de40008/skold_peter_2840_210914_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/d96fc1ee79e947f2b3717dfc6de40008/skold_peter_2840_210914_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Peter Sk&ouml;ld, advisor to the Vice-Chancellor on Arctic and International Affairs and the new Chair of the EPB.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p>He has also played a key role in relocating the EPB Secretariat from The Hague to Ume&aring;. In addition, efforts are now being intensified to collaborate with the European Commission in establishing the European Polar Coordination Office (EPCO) in connection with the Arctic platform currently under full development at Ume&aring; University.&nbsp;</p><p>"Leading the EPB is an inspiring task," says Peter Sk&ouml;ld. "It is crucial to strengthen interdisciplinary perspectives to address the complex challenges faced by the polar regions, both environmentally and socially."</p><h3>Ume&aring; University &ndash; A Growing Force in Polar Research</h3><p>By establishing the EPB Secretariat in Ume&aring;, the university is solidifying its position as a significant actor in polar research and international collaboration.</p><p>"The relocation of the EPB Secretariat to Ume&aring; is a recognition of the university&rsquo;s expertise and our commitment to polar research," continues Sk&ouml;ld. "It opens up new opportunities for collaboration and innovation, both for our researchers and with our international partners."</p><p>EPB comprises 31 member organisations from 22 countries and works to strengthen European coordination in polar research through information sharing, infrastructure optimisation, and joint initiatives. With Peter Sk&ouml;ld as Chair and the EPB Secretariat at Ume&aring; University, the university is well-positioned to tackle future challenges and opportunities in polar research.</p>/en/news/peter-skold-appointed-chair-of-the-european-polar-board_12009801//en/news/vr-millions-to-dismantle-virus-factories_12006740/The Faculty of Medicine at Umea university wants to give this week attention as an important indicator of base values and we take the opportunity to present Isabel Goicolea, professor at the department of Epidemiology and Global Health, whose research to a great deal concerns gender based violence.Wed, 20 Nov 2024 10:59:12 +0100<div class="mediaflowwrapper bildlink halfwidthsquareleft"><div class="bildImage"><picture><source srcset="/contentassets/cb7d8a0b7f6a48158809cd9f8492b708/goicolea_isabel_0501_200821_mpn.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/cb7d8a0b7f6a48158809cd9f8492b708/goicolea_isabel_0501_200821_mpn.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/cb7d8a0b7f6a48158809cd9f8492b708/goicolea_isabel_0501_200821_mpn.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/cb7d8a0b7f6a48158809cd9f8492b708/goicolea_isabel_0501_200821_mpn.jpg?mode=crop&amp;width=640 640w, /contentassets/cb7d8a0b7f6a48158809cd9f8492b708/goicolea_isabel_0501_200821_mpn.jpg?mode=crop&amp;width=854 854w, /contentassets/cb7d8a0b7f6a48158809cd9f8492b708/goicolea_isabel_0501_200821_mpn.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Professor vid Institutionen f&ouml;r epidemiologi och global h&auml;lsa</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p><strong>Isabel, please tell us a bit about your research and how it relates to this particular week!&nbsp;</strong></p><p>Our research (because it&rsquo;s not only I) deals with how social and health care services respond to gendered violence. We, for example, analyse the reasons behind why despite all the efforts to incorporate routine questions about violence within health care and social services, few women disclose ongoing violence to health care professionals or social workers.</p><p>Trust is a crucial aspect here: women need to trust health care and social services&rsquo; professionals to be able to tell their stories, they need to feel validated and that they get the support they need. Unfortunately, and despite the motivation and great work of many professionals, there are many challenges to developing and sustaining trust in welfare institutions, and without such trust it becomes impossible to disclose violence and to accept support. That is what we are studying: what challenges trust between victims/survivors of violence and welfare institutions and how can we enhance trust.</p><p><strong>How can the university in general and the faculty of medicine in particular work to help prevent gender based violence?</strong></p><p>It is crucial to recognize that such violence exists and affects students and staff at the university. Even more, we need to acknowledge that certain characteristics of academia, like hierarchies, authority, power, contribute to sustain gendered violence, and make it harder for victims/survivors to denounce.</p><p>We need to make sure that victims/survivors of gendered violence in academia can complain and that when they do, they feel listened to, trusted, validated and supported. But also, that the burden is not put on victims/survivors to be brave and denounce; instead it should be a shared responsibility between all of us to make academia a safer environment, one where we all feel compelled to complain if we think something is unfair or wrong, and where we all contribute to minimizing the hierarchial and power structures that sustain gendered &nbsp;violence. The higher in the hierarchy the more responsibility we should have to speak up and contribute to eliminate gendered violence.</p><p>The other important aspect is that at the Faculty of Medicine we have the responsibility to train the next generation of health care professionals: they need to finish their education knowing that responding to gendered violence is also the responsibility of the healthcare system, and what they can do within the health care system to better support victims/survivors of gendered violence. We are integrating teaching on gendered violence, both to understand its pervasiveness, gendered roots, its global impact, as well as what works when it comes to health care responses. This is a particularly important contribution, since gendered violence is also a health problem, and victims/survivors of violence reach health care services more often than any other public institutions.</p><p><strong>If you would pick one of the activities this week in V&auml;sterbotten, what would you recommend?</strong></p><p>It is great that there are many, and with different focus, because gendered violence touches many arenas. I would suggest joining the demonstration on the 25th of November, which is a great way to show support for eliminating gendered violence, and it is a demonstration that unites many cities around the world on that day.</p><p>The 25th of November has been celebrated by feminist activists since 1960 in honour of the Mirabal sisters, three political activists from the Dominican Republic who were brutally murdered in 1960 by order of the country's ruler, Rafael Trujillo (1930-1961).</p><p>Participating on the demonstration in Ume&aring; is also a way to show support for the feminist shelter movement (Kvinno and Tjejjouren), and to recognize that it was feminist activism that put, and struggles to keep, this problem in the agenda.</p>/en/news/a-week-free-from-violence_12007222//en/news/umea-university-hosted-scilifelab-leadership-for-a-full-day-tour-of-local-facilities_12006806/Last week Umeå University hosted the new director for SciLifeLab, Jan Ellenberg, and SciLifeLab board chair Ylva Engström, for a full-day visit of Umeå and our facilities. The day included tours of the local research infrastructures, lunch with representatives of the University and meetings with the staff scientists who make the infrastructures accessible for national users within life science. Tue, 19 Nov 2024 08:40:24 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_13.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_13.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_13.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_13.jpg?mode=crop&amp;width=640 640w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_13.jpg?mode=crop&amp;width=854 854w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_13.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>The new director for SciLifeLab, Jan Ellenberg, and SciLifeLab board chair Ylva Engstr&ouml;m, visited Ume&aring; for a full-day tour of infrastructures and meetings with members. Seen here with Tobias Sparrman, Jurgen Schleucher and Gerhard Gr&ouml;bner in the NMR Core facility.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Rebecca Forsberg</span></div></div><p class="quote-center">The staff is key in running the infrastructures for the greater good of life science research</p><p>SciLifeLab, a national wide resource of sophisticated technologies and expertise available to researchers in life science, has since 2022 expanded with several local sites in Sweden, including Ume&aring;.&nbsp; By connecting the already existing cutting-edge infrastructures at Ume&aring; with the national network, our community of researchers in areas such as biomedicine, ecology and evolution expands.&nbsp;<br>&nbsp;<br>As of this summer, SciLifeLab has a new director, Jan Ellenberg, who visited the site in Ume&aring; for a full day of activities. The site director Linda Sandblad, Associate Professor at the Department of Chemistry and director of Ume&aring; Center for Electron Microscopy (UCEM), kicked the day off with an introduction of SciLifeLab in Ume&aring;, highlighting the strengths of the infrastructures being integrated with two universities, Ume&aring; University and SLU, as well as Region V&auml;sterbotten through University Hospital of Ume&aring; (Norrlands Universitetssjukhus, NUS). &nbsp;</p><p>&ldquo;Meeting Jan Ellenberg on site in Ume&aring; was important for us. Jan&rsquo;s experience of international research infrastructure development for&nbsp;life science is valuable for the continued development here in Ume&aring;.&nbsp;Now, when he knows both staff scientists and our facilities, we can work more effectively together&rdquo;, says Linda Sandblad.&nbsp;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_22.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_22.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_22.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_22.jpg?mode=crop&amp;width=640 640w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_22.jpg?mode=crop&amp;width=854 854w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_22.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Tobias Sparrman and Jurgen Schleucher shows Jan Ellenberg one of the many state-of-the-art instruments at NMR.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Rebecca Forsberg</span></div></div><p><br>&nbsp;Tours of infrastructures started at the Swedish NMR Centre, followed by a meeting with Chemical Biology Consortium Sweden (CBCS), tours of Swedish Metabolomics Centre (SMC) and the Data Science Node, including High Performance Computer Center North (HPC2N), National Bioinformatic Infrastructure Sweden (NBIS), and Data Driven Life Science (DDLS). Although much to see, there was still room for coffee and visits in some of the labs where the life science research takes place. &nbsp;</p><p>&ldquo;The staff is key in running the infrastructures for the greater good of life science research, and meeting the people who do the work at the sites is very important and something I cherish&rdquo;, Jan Ellenberg said, stressing the importance of working together across the sites in order to both overcome shared problems, and achieve shared ambitions and goals.&nbsp;<br>&nbsp;<br>During the lunch with Ume&aring; University representatives, including vice-chancellor Hans Adolfsson, and Mikael Elofsson, Dean at the Faculty of Science and Technology, Jan Ellenberg took the opportunity to present himself and his visions for how SciLifeLab and Ume&aring; will strenghten its connections further. Jan Ellenberg provides great inspiration on how infrastructure and large scall research projects can synergise&rdquo;, said Linda Sandblad. &nbsp;</p><p>The lunch followed with facility tours at Clinical Genomics and UCEM. To summarise the visit, the delegation from SciLifeLab met with staff from Ume&aring; University, to identify possibilities and map out ideas for the future, in order to make life science infrastructures accessible to as many as possible.&nbsp;&nbsp;</p><p>&ldquo;I feel that here in Ume&aring; you have realised that there is much to gain from working together, with people coming together from different departments and areas of expertise, in order to create the infrastructures and facilities that are needed for the good of life science research&rdquo;, Jan Ellenberg concluded. &nbsp;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_32.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_32.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_32.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_32.jpg?mode=crop&amp;width=640 640w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_32.jpg?mode=crop&amp;width=854 854w, /contentassets/b0bfe9b349884b85b48537a0645cd864/scilifelab_visit_32.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Annika Johansson, Head of Unit at the Swedish Metabolomics Centre (SMC) shows Jan Ellenberg and Ylva Engstr&ouml;m the lab in Ume&aring;.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Rebecca Forsberg</span></div></div>/en/news/umea-university-hosted-scilifelab-leadership-for-a-full-day-tour-of-local-facilities_12006806//en/news/kbc-days-strengthens-interdisciplinary-collaboration_12005601/Öppet hus on 6 November is Umeå University's opportunity to show what it's like to study at one of Sweden's largest universities. High school students and others interested in studying from Ljusdal to Kalix arrive with forty buses and get information about everything from programmes and student rooms to entertainment and training opportunities, as well as the chance to visit the Arts Campus. And it's another attendance record with over 3,800 registered and over 4,000 visitors in total.Thu, 31 Oct 2024 12:08:55 +0100<div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/f38e793e55ed4211b8908714285ef917/lofgren_susanna_4312_231004_hkn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/f38e793e55ed4211b8908714285ef917/lofgren_susanna_4312_231004_hkn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/f38e793e55ed4211b8908714285ef917/lofgren_susanna_4312_231004_hkn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/f38e793e55ed4211b8908714285ef917/lofgren_susanna_4312_231004_hkn2.jpg?mode=crop&amp;width=640 640w, /contentassets/f38e793e55ed4211b8908714285ef917/lofgren_susanna_4312_231004_hkn2.jpg?mode=crop&amp;width=854 854w, /contentassets/f38e793e55ed4211b8908714285ef917/lofgren_susanna_4312_231004_hkn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Susanna L&ouml;fgren, project manager at the Communications Office at Ume&aring; University. Photo: Hans Karlsson.</p></div></div><p>"It's a solid programme that meets the more than four thousand people interested in studying, teachers and study and career counsellors who come to visit. There will be over one hundred and thirty information sessions on study programmes, and a lot of university staff are working to the last minute on the preparations," says Susanna L&ouml;fgren, project manager at the Communications Office at Ume&aring; University.</p><p>In addition to lectures on different programmes, visitors are invited to try out various activities and clever experiments. Guided tours are also offered to the Artistic Campus by the river and the Iksu training facility, as well as the neighbouring Swedish University of Agricultural Sciences (SLU), which is also present in Lindellhallen at Ume&aring; University. Student and career counsellors and other staff also receive their own skills development during a lunch meeting with the university's education leaders.</p><p>"We know from our evaluations that the open house is both an appreciated and effective way of communicating our activities, so even though it's a lot of work and a lot of people involved from Ume&aring; University, it's really worth all the effort. It is also very rewarding to meet all those interested in studying, who are often very curious about both student life and what it is like to study at a university," says Susanna L&ouml;fgren.</p><p>One part of student life that always gets a lot of attention is student housing, and the municipal housing company Bostaden is therefore also on site, showing what a student room looks like and telling everything about how the prospective students should go about solving the housing issue.</p><p>"Students are a very important target group for us and for us it is very valuable to meet prospective students, partly to tell them about our more than 4,200 student housing units, but also to hear their thoughts and expectations. At our stand, the focus is on getting as many people as possible to join our housing queue and we also show what a student room looks like in real size. Of course, we also take the opportunity to welcome all young people to our beautiful city," says Anders Hugosson, Marketing Manager at Bostaden.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/f38e793e55ed4211b8908714285ef917/oppethus_7971_221109_lgn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/f38e793e55ed4211b8908714285ef917/oppethus_7971_221109_lgn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/f38e793e55ed4211b8908714285ef917/oppethus_7971_221109_lgn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/f38e793e55ed4211b8908714285ef917/oppethus_7971_221109_lgn2.jpg?mode=crop&amp;width=640 640w, /contentassets/f38e793e55ed4211b8908714285ef917/oppethus_7971_221109_lgn2.jpg?mode=crop&amp;width=854 854w, /contentassets/f38e793e55ed4211b8908714285ef917/oppethus_7971_221109_lgn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>The student room in real size at &Ouml;ppet hus 2023. Photo: Lizette Gunnesson.</p></div></div><p>"We look forward to welcoming all these visitors to the university and hope that everyone who comes will have an informative and inspiring day. Our hope is that many will be so inspired that they will return in a year or two as students at Ume&aring; University or at another university," says Susanna L&ouml;fgren.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="e5be002c-0911-49df-9d68-3914f06756cb" data-contentname="Öppet hus 2024 engelska">{}</div>/en/news/record-number-of-people-interested-in-studying-come-to-visit_12000462//en/news/persson-millions-for-intestinal-research_11998529/Björn Schröder's research group has received SEK 6 million in grants from the Erling Persson Foundation for research on the intestinal microbial modulation of mucus in ulcerative colitis.Mon, 28 Oct 2024 16:51:05 +0100<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/ae192f41493e43708a08e34a498afb40/schroder_bjorn_5343_190405_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ae192f41493e43708a08e34a498afb40/schroder_bjorn_5343_190405_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ae192f41493e43708a08e34a498afb40/schroder_bjorn_5343_190405_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ae192f41493e43708a08e34a498afb40/schroder_bjorn_5343_190405_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/ae192f41493e43708a08e34a498afb40/schroder_bjorn_5343_190405_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/ae192f41493e43708a08e34a498afb40/schroder_bjorn_5343_190405_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Bj&ouml;rn Schr&ouml;der, professor and research groupl leader. <br><span class="bildPhotografer" style="white-space: nowrap;"><span class="photo">Image</span>Mattias Pettersson</span></p></div></div><p>Ulcerative colitis is a chronic inflammatory disease of the colon that is becoming increasingly common in industrialized countries. Because the exact cause of the disease is still unknown, current treatments are primarily focused on symptom relief rather than offering a cure. Notably, people with ulcerative colitis often exhibit an imbalanced gut microbiota and deficiencies in the protective mucus layer.</p><p>The research in Bj&ouml;rn Schr&ouml;der's group at the Department of Molecular Biology and the Laboratory of Molecular Infection Medicine Sweden &ndash; MIMS focuses on the sticky mucus layer that covers the surface of the intestine and protects against the billions of microorganisms, which could otherwise lead to infections and inflammation. The project aims to elucidate the interaction between this gut flora and mucus defects that have been observed in people with ulcerative colitis. The research is carried out in collaboration with researchers at the Department of Clinical Sciences and the Department of Food and Nutrition Science to study the impact of bacteria and diet on the course of the disease. The hope is to identify which bacteria are beneficial for mucus function and thus eventually lead to the development of a new generation of probiotics to prevent and treat ulcerative colitis.</p><p>The project will run for three years. </p>/en/news/persson-millions-for-intestinal-research_11998529//en/news/proteins-are-key-when-antibiotic-resistance-spreads_11997030/Antibiotic resistance is a growing public health problem globally. The problem is exacerbated by the fact that some bacteria that have become resistant to antibiotics have the ability to spread the resistance to other bacteria via secretion systems. A new thesis at Umeå University analyzes how special proteins are used in this process where antibiotic resistance spreads.Tue, 22 Oct 2024 08:43:49 +0200<p>"The results contribute to a deeper understanding of the system for how genetic material is transported from one bacterium to another. This is important for understanding how bacteria can spread, among other things, antibiotic resistance. Hopefully, this research can become a small piece of the puzzle in the work to eventually find drugs that can prevent this spread", says Annika Breidenstein, PhD student at the Department of Medical Chemistry and Biophysics at Ume&aring; University.</p><p>Modern medicine is based on access to antibiotics that can counteract infectious diseases and enable operations such as transplants and many cancer treatments. Without effective antibiotics, one would often get serious, sometimes life-threatening, infections after surgical procedures.</p><p>In recent decades, more and more bacteria have stopped responding to antibiotics; they have become resistant. This is due to the overuse of antibiotics, not only in healthcare but also in animal husbandry, where healthy animals are given antibiotics to prevent disease in tightly packed environments. In addition to developing antibiotic resistance, many bacteria can also spread this resistance to other bacteria. This takes place with the help of a protein machinery known as the type IV secretion system.</p><p>Annika Breidenstein's thesis focuses on these systems. Since there are many different types of bacteria, the main question was what these different secretion systems have in common and in what ways they differ.</p><p>Most of the genetic material of bacteria is packed into a long, circular DNA molecule. However, type IV secretion systems and antibiotic resistance are often found on extra, more mobile DNA called plasmids. A study in the thesis deals with how plasmids are prepared for transport to other bacteria with type IV secretion systems. For this, a protein called relaxase is needed, which binds to the plasmid. X-rays were used to produce a detailed picture of a relaxase that binds DNA. The relaxase binds better to DNA when it is assisted by another protein and it was also investigated how these two proteins interact.</p><p>Usually DNA, and thus also plasmids, consists of two strands. However, the relaxase only binds to one of the strands, and it is only this that is transported to the next bacterium. Annika and the research group she is part of suspected that a protein called PrgE is important for this process, as they believed that it binds this particular single-stranded DNA. Therefore, they also produced images of this protein, which showed exactly how the protein binds to DNA. However, PrgE was found to bind to both single- and double-stranded DNA. The conclusion was that PrgE does not have the expected function and is not directly involved in DNA transport.</p><p>The question remained - what all type IV secretion systems have in common. To answer this, the researchers used new bioinformatics methods, which partly use artificial intelligence. Using a database they created for the purpose, they were able to identify which proteins generally look the same in all known type IV secretion systems. Using this knowledge and artificial intelligence, a model of what a type IV secretion system could look like was built. With the help of this, it will be possible to better understand the secretion systems that are currently not known much about, but which we know are important in hospital infections.</p><p><em>Annika Breidenstein grew up in Germany and did her master's degree in infection biology at Uppsala University.</em></p>/en/news/proteins-are-key-when-antibiotic-resistance-spreads_11997030//en/news/systems-for-quality-in-medical-research_11993671/The Faculty Board of the Faculty of Medicine has established a quality system for research at the faculty to develop and ensure the quality of research. Tue, 22 Oct 2024 10:33:28 +0200<p>The Faculty of Medicine's quality system for research is based on Ume&aring; University's policy for quality development and quality assurance of research. The policy, in turn, is based on both the common framework for higher education institutions' quality assurance and quality development of research that the Association of Swedish Higher Education Institutions (SUHF) has developed and on Ume&aring; University's vision, which was adopted by the University Board on 2019-04-03.</p><p>Ume&aring; University's policy includes the following four components of quality work:</p><p>A. Culture of quality in research<br>B. Resources for quality in research<br>C. Strategic choices and priorities for research development and renewalD. Follow-up, analysis and evaluation</p><p>The Faculty of Medicine's organisation and governing documents, such as rules of procedure and decision-making and delegation of authority, describe both the line organisation and the division of responsibilities and roles within the faculty. Through the faculty's current organisation and governance, strengths, development opportunities and weaknesses are identified.</p><p>An example of this is that the faculty management is represented in several of the faculty's meeting bodies, which provides a close link between the faculty and department levels and good opportunities for discussion about quality work in research at different levels.</p><p><a title="To Quality System " href="~/link/f9d4c52081b5426aab609aa5b64fbd69.aspx">To Quality System</a></p>/en/news/systems-for-quality-in-medical-research_11993671//en/news/important-new-funding-for-research-on-virus-factories_11994805/Lars-Anders Carlson is receiving SEK 24 million from the Knut and Alice Wallenberg Foundation to understand how the virus factories that are built up in our cells work. "I remember the first meeting we had before the application with everyone involved over Zoom, it was in the middle of a brunch on my holiday in September 2023 and the coffee got cold, but it was worth it," says Lars-Anders Carlson, Associate professor at Department of Medical Biochemistry and Biophysics. Tue, 15 Oct 2024 12:49:48 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/ce9a18c25793425ca607e0ce9f45cafa/carlson_lars-anders_620_13092024_hkn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/ce9a18c25793425ca607e0ce9f45cafa/carlson_lars-anders_620_13092024_hkn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/ce9a18c25793425ca607e0ce9f45cafa/carlson_lars-anders_620_13092024_hkn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/ce9a18c25793425ca607e0ce9f45cafa/carlson_lars-anders_620_13092024_hkn3.jpg?mode=crop&amp;width=640 640w, /contentassets/ce9a18c25793425ca607e0ce9f45cafa/carlson_lars-anders_620_13092024_hkn3.jpg?mode=crop&amp;width=854 854w, /contentassets/ce9a18c25793425ca607e0ce9f45cafa/carlson_lars-anders_620_13092024_hkn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Lars-Anders Carlson is receiving SEK 24 million from the Knut and Alice Wallenberg Foundation to understand how the virus factories that are built up in our cells work. Photo: Hans Karlsson</p></div></div><p>The project Lars-Anders Carlson will lead is called <em>Conserved concepts and divergent details of membrane-bound viral replication organelles</em> and he explains it briefly as follows:</p><p>"When the virus enters a cell, it must use the cell to replicate. But to do that, it has to rebuild inside the cell and optimise the cell to become what we can call a virus factory. The project aims to understand how this virus factory inside an infected cell is organised and how it works."</p><p>Viruses can infect both humans and animals and lead to a wide range of diseases, such as Covid and TBE, and the team will study and compare the virus factories of two major groups of viruses spread by mosquitoes and ticks.</p><p>"Our research is curiosity-driven basic research on a key part of the virus life cycle. In the long run, we hope to contribute with pieces of the puzzle that can lead to new forms of treatment."</p><h3>From California to Ume&aring;</h3><p>One of the main reasons why Lars-Anders Carlson conducts his research in Ume&aring; is due to the advanced electron microscopes that Ume&aring; University can offer today. Lars-Anders Carlson's scientific journey otherwise started at Uppsala University, he did his PhD in Munich and his postdoc at the National Institute of Health in Washington DC and at the University of California in Berkeley, before moving to Ume&aring; in 2016 for a position at the Wallenberg Centre for Molecular Medicine (WCMM).</p><p>"What we will do with the electron microscopes is to take three-dimensional close-ups of the viruses and thus learn more. Now I'm really looking forward to getting started and hiring and bringing new PhD students and researchers into the project!"</p><h3>Research is teamwork</h3><p>Lars-Anders Carlson emphasises that research is a team effort and wants to highlight everyone involved, mentioning Anna &Ouml;verby Wernstedt, Department of Clinical Microbiology, and Richard Lundmark, Department of Medical and Translational Biology, both at Ume&aring; University. From Karolinska Institutet, Gerald McInerney, Department of Microbiology, Tumour and Cell Biology, and Benjamin Murrell, Department of Microbiology, Tumour and Cell Biology, are involved. Within the project, they will also collaborate with Andreas Carlson, Department of Mathematics, University of Oslo, who will create mathematical models.</p><p>"The great thing about receiving a grant from the Knut and Alice Wallenberg Foundation is that it is such a clear stamp of quality; each project is evaluated by at least four or five international experts in the respective field and must <em>have such high scientific potential that they have the possibility of leading to future scientific breakthroughs</em>. The fact that they have chosen our project as one of the best feels very good, of course. This will be so damn fun!"</p>/en/news/important-new-funding-for-research-on-virus-factories_11994805//en/news/new-findings-on-stem-cells-and-development-of-cancer_11993062/A study led by Umeå University, Sweden, presents new discoveries about how stem cells develop and transition into specialised cells. The discovery can provide increased understanding of how cells divide and grow uncontrollably so that cancer develops.Thu, 10 Oct 2024 10:15:43 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/7969a602231041e59d8fc5ec89275b6a/sandhya_malla_och_kanchan_kumari3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/7969a602231041e59d8fc5ec89275b6a/sandhya_malla_och_kanchan_kumari3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/7969a602231041e59d8fc5ec89275b6a/sandhya_malla_och_kanchan_kumari3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/7969a602231041e59d8fc5ec89275b6a/sandhya_malla_och_kanchan_kumari3.jpg?mode=crop&amp;width=640 640w, /contentassets/7969a602231041e59d8fc5ec89275b6a/sandhya_malla_och_kanchan_kumari3.jpg?mode=crop&amp;width=854 854w, /contentassets/7969a602231041e59d8fc5ec89275b6a/sandhya_malla_och_kanchan_kumari3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Two of the researchers behind the study, Sandhya Malla and Kanchan Kumari, in the Aguilo lab.</p><span class="bildPhotografer"><span class="photo">Image</span>Poonam Baidya</span></div></div><p>"The discovery opens a new track for future research into developing new and more effective treatments for certain cancers," says Francesca Aguilo, associate professor at the Department of Molecular Biology at Ume&aring; University and leader of the study.</p><p>All cells in the body arise from a single fertilized egg. From this single origin, various specialized cells with widely differing tasks evolve through a process called cellular differentiation. Although all cells share the same origin and share the same genetic information, specialized cells use the information in different ways to perform different functions. This process is regulated by genetic and epigenetic mechanisms.</p><p>In the current study, researchers have studied embryonic stem cells from mice to understand how the cells transition from a versatile state to become specialized cells. A key player in this process is the protein LSD1. It is overexpressed in many cancers and is therefore an important goal in cancer treatment research. Several clinical trials are testing to inhibit the LSD1 protein's ability to modify gene expression.</p><p>However, the study shows that LSD1 not only affects gene expression in the way previously assumed by altering histones, i.e. proteins around which the long DNA helixes of chromosomes are coiled, but LSD1 also acts as a scaffold, a support structure for other proteins that control DNA methylation. The researchers were able to see that even when LSD1's enzymatic function was inhibited, its support ability could still maintain DNA methylation patterns necessary for cell differentiation and proliferation. Abnormal DNA methylation is strongly associated with cancer.</p><p>The results suggest that, for cancer treatments to be effective, it may not be enough to simply target blocking LSD1's enzymatic activity. Treatments may also need to focus on also attacking LSD1's supporting role.</p><p>"So far, this is basic research, so there is a long way to go and it is too early to make any promises about new treatments, but it could be an important step for continued cancer research," says Francesca Aguilo.</p><p>The study has been led from Ume&aring; University in collaboration with various institutions including the University of Pavia, University of Texas Health Science Center at Houston, Universidad de Extremadura, and others. It is published in the scientific journal Nature Communications.</p><p>The study is funded by the Swedish Research Council, the Swedish Cancer Society, the Knut and Alice Wallenberg Foundation and the Kempe Foundations.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/7969a602231041e59d8fc5ec89275b6a/aguilo_francesca_6437_201021_mpn3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/7969a602231041e59d8fc5ec89275b6a/aguilo_francesca_6437_201021_mpn3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/7969a602231041e59d8fc5ec89275b6a/aguilo_francesca_6437_201021_mpn3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/7969a602231041e59d8fc5ec89275b6a/aguilo_francesca_6437_201021_mpn3.jpg?mode=crop&amp;width=640 640w, /contentassets/7969a602231041e59d8fc5ec89275b6a/aguilo_francesca_6437_201021_mpn3.jpg?mode=crop&amp;width=854 854w, /contentassets/7969a602231041e59d8fc5ec89275b6a/aguilo_francesca_6437_201021_mpn3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Francesca Aguilo has led the study.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-left">too early to make any promises</p><p>"So far, this is basic research, so there is a long way to go and it is too early to make any promises about new treatments, but it could be an important step for continued cancer research," says Francesca Aguilo.</p><p>The study has been led from Ume&aring; University in collaboration with various institutions including the University of Pavia, University of Texas Health Science Center at Houston, Universidad de Extremadura, and others. It is published in the scientific journal Nature Communications.</p><p>The study is funded by the Swedish Research Council, the Swedish Cancer Society, the Knut and Alice Wallenberg Foundation and the Kempe Foundations.</p>/en/news/new-findings-on-stem-cells-and-development-of-cancer_11993062//en/news/children-line-up-to-build-a-bacteria-in-3d_11991220/Umeå researcher Kemal Avican participated in Curiosum's researcher's night within the ForskarFredag initiative September 27th. Kemal and his team adapted a VR simulation tool developed with InfraVis into an outreach prototype for exploring bacteria with children. Here Kemal shares his experience of the event and offers some tips for inspiring children in science. Tue, 08 Oct 2024 15:43:53 +0200<p class="quote-center">It was amazing to see kids queuing and patiently waiting for a long time to see the bacteria!</p><h3><strong>What did you do during the event?</strong></h3><p>"We generated a 3D model of bacteria within a Metaverse environment in collaboration with Mattis Lindmark from Humlab, Ume&aring; University and InfraVis. This was a pilot project to simulate gene expression regulation in pathogenic bacteria under different conditions. We then realized this could be a great pedagogical tool for teaching bacterial genetics and physiology. We created this prototype of 3D bacteria for the public to see what happens in different compartments of bacteria when they face changes in the environment."</p><h3><strong>What was a highlight from the event?</strong></h3><p>"I was happy to see the huge interest in the organization, reflecting the curiosity in society. At our station, I expected some interest since kids enjoy 3D games, but the enthusiasm was beyond my expectations. It was amazing to see kids queuing and patiently waiting for a long time to see the bacteria."</p><h3>How did you feel after the event?</h3><p>"After the event, I felt incredibly satisfied and proud of my team and collaborators. It was rewarding to see the high level of interest andengagement from the public, especially the kids. Their enthusiasm and curiosity about our 3D bacteria model paid off the work we put into the project."</p><p><h3>What did you learn from your experience?</h3><p>"I learned that younger kids are incredibly adept at building bacteria in the Metaverse. Their creativity seems less constrained by the rules of our reality, which often limits our own creativity. This experience showed me how important it is to create an environment where imagination can grow without limits."</p><h3>Do you have any tips for a researcher starting out in outreach at ForskarFredag?</h3><p>"Be ready for a large number of visitors, especially kids who are eager to learn and interact. Break down complex scientific ideas into simpler, more digestible pieces to make them accessible to a broader audience and use tools that kids love."</p>/en/news/children-line-up-to-build-a-bacteria-in-3d_11991220//en/news/ndpia--important-player-at-the-infection-biology-arena_11990087/The National Doctoral Programme in Infections and Antibiotics, NDPIA, covers infection biology in a broad sense, from humans and animals to plants and is a success story. Since the first student enrolled in 2014, the research school has hosted more than 700 PhD student and postdoc members.Thu, 03 Oct 2024 15:22:30 +0200<div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1045-240927-mpn.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1045-240927-mpn.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1045-240927-mpn.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1045-240927-mpn.jpg?mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1045-240927-mpn.jpg?mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1045-240927-mpn.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>In the NDPIA research school, Debra Milton works closely with the project coordinator, Hanna Eriksson.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><p class="quote-center">&nbsp;I hope that NDPIA has played a small role in their continued interest in research</p><p>With a solid experience from running two prior research schools at Ume&aring; University, Professor Debra Milton was appointed director of the research school in 2020.</p><p>&ldquo;I absolutely enjoy this work! I meet so many amazing scientists and learn new state-of-the-art techniques in infection biology,&rdquo; says Debra Milton, professor at the Department of Molecular Biology at Ume&aring; University.</p><p>NDPIA was initiated by The Laboratory for Molecular Infection Medicine Sweden, MIMS, in Ume&aring;. Professors Bernt Eric Uhlin and &Aring;ke Forsberg organised a joint application between six national universities and institutes for a 2013 Swedish Research Council (Vetenskapsr&aring;det) call for funding a research school focused on infection biology.</p><p>The application was successful, and the six Swedish partner universities received an initial 15 million SEK to establish and run the new research school. In 2016, the funding was prolonged for another 5 years with an additional 10 million SEK. In 2021, a further extension for use of the funding through 2024 was granted due to the COVID-19 pandemic. &Aring;ke Forsberg was the first national director from 2013-2019.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1061-240927-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1061-240927-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1061-240927-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1061-240927-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1061-240927-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1061-240927-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Current NDPIA director Debra Milton gets very involved in the courses; she is creative and has lots of ideas aiming to meet the needs of young researchers.&nbsp;</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><h2 id="info0" data-magellan-target="info0">Good reputation</h2><p>PhD students and postdocs enrolled at a Swedish university or at one of NDPIA&rsquo;s&nbsp;international partners&nbsp;and studying infection biology and/or antibiotics are welcome to&nbsp;apply for a membership in NDPIA.</p><p>The NDPIA-organized courses are a core activity of the programme and are either free of charge or co-funded by NDPIA. Each course enrols 25-40 members, and the students may receive ECTS credits at their home university for their participation.</p><p>&ldquo;Our courses are often fully booked and very well received. We have a good reputation; a good token is that the students participate in more than one course and the courses receive interest from international students,&rdquo; says Debra Milton.</p><p>Throughout the years, the courses have been held in many different sites within Sweden.</p><p>&ldquo;Now, we hold the courses most often at a venue, which allows the students to focus on a topic for 3-5 days and to present poster presentations. We have experienced that hosting a course at a conference centre leads to a relaxed atmosphere with more time to network and to discuss with other participants and lecturers, who are national and international experts within the course topic. In this way the students build up their scientific network. That is quality time!&rdquo;</p><p>By attending the NDPIA courses, students have stated that they have gained new ideas and directions for their research and some students have established new research collaborations with other labs in Sweden or international labs.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-ai-course-2024-workshop.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-ai-course-2024-workshop.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-ai-course-2024-workshop.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-ai-course-2024-workshop.jpg?mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-ai-course-2024-workshop.jpg?mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-ai-course-2024-workshop.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Assistant Professors Paul Jensen from University of Michigan, USA, and Mark Hendricks from Whitman College, USA, held a workshop in automated science during the NDPIA course "AI Applications in Infection Biology." The exercise involved finding the best set of catapult factors that resulted in a launched ball landing as close to an arbitrary target as possible. The students trained a Gaussian Process regression to try and model the experiment space.</p><span class="bildPhotografer"><span class="photo">Image</span>Hanna Eriksson</span></div></div><h2 id="info1" data-magellan-target="info1">Designing state-of-the-art courses</h2><p>A lot of work is put in to designing these courses from scratch, and this is a major part of Debra Milton&rsquo;s work as director. This work is something she does alongside her teaching at the university. Debra Milton gets very involved in the courses; she is creative and has lots of ideas aiming to meet the needs of young researchers.</p><p>&ldquo;I review many articles to find new and hot topics in infection biology. For instance, a new course we gave this year was entitled &lsquo;AI Applications in Infection Biology,&rsquo; which introduced the students to methods on how to use AI in the lab via three hands-on workshops. Other popular course titles are &lsquo;Microbiota and Health,&rsquo; &lsquo;Basic and Applied Phage Biology,&rsquo; and &lsquo;Antibiotics and Antibiotic Resistance.&rsquo;&rdquo;</p><p>She continues:</p><p>&ldquo;My vision has been to offer a portfolio of high-quality courses in infection biology that are given biannually. Now, we have seven courses on rotation, and we keep adding new courses. A course on CRISPR-Cas9 applications in infection biology is on my list to develop for the future.&rdquo;</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-amr-course-2024-lecture.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-amr-course-2024-lecture.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-amr-course-2024-lecture.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-amr-course-2024-lecture.jpg?mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-amr-course-2024-lecture.jpg?mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/ndpia-amr-course-2024-lecture.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Professor Diarmaid Hughes from Uppsala University gives a lecture on "Resistance from a microbe perspective" during the NDPIA course "Antibiotics and Antibiotic Resistance" - one of the most popular courses held at Stora Br&auml;nnbo in Sigtuna, 2024.</p><span class="bildPhotografer"><span class="photo">Image</span>Hanna Eriksson</span></div></div><h2 id="info2" data-magellan-target="info2">Teamwork and cherry-picking</h2><p>However, designing and organizing a course is a team effort and Debra&rsquo;s helping team is critical for producing a quality course and for finding top international scientists to provide the lectures. National expert researchers on the course topic, who are willing to help, work together with NDPIA to create a course schedule with possible lecturer names.</p><p>&ldquo;We cherry-pick national and international renowned scientists to invite, but as the professors are always super busy, it is important to have a pool of names for each lecture.&rdquo;</p><p>In addition to designed courses, NDPIA subscribes to training courses in graphic design to visualise science and to a suite of 26 on-demand courses with topics from designing an experiment to advancing a career provided by Nature Masterclasses from Springer Nature.</p><div class="mediaflowwrapper bildlink"><div class="bildImage"><picture><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1049-240927-mpn2.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1049-240927-mpn2.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1049-240927-mpn2.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1049-240927-mpn2.jpg?mode=crop&amp;width=640 640w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1049-240927-mpn2.jpg?mode=crop&amp;width=854 854w, /contentassets/85945fd4e8ea4ce18180f96f3f36c9a0/debra_och_hanna_1049-240927-mpn2.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Every course is documented in a booklet.</p><span class="bildPhotografer"><span class="photo">Image</span>Mattias Pettersson</span></div></div><h2 id="info3" data-magellan-target="info3">Generous support strengthens infection research</h2><p>Furthermore, by&nbsp;co-funding&nbsp;of travel and accommodation costs, NDPIA supports short research stays in Sweden or abroad, and participation in the biannual National Infection Biology Meeting. This conference is an important network meeting for all NDPIA members and is organized jointly with the Swedish National Infection Biology network and the Swedish Society for Microbiology.</p><p>&ldquo;I do believe what is most unique with our research school is that the financial support from the Swedish Research Council has been so generous and has allowed us to strengthen the national, and even international, network for Swedish infection biologists to attract young scientists to this field of research.&rdquo;</p><p>At the end of this year, Debra Milton retires and Annasara Lenman, associate professor at the Department of Clinical Microbiology at Ume&aring; University, will become the new director of the research school.</p><p>&ldquo;For sure I will miss my job, but I will also find time for other things! I will take up sewing again, cooking, read books especially on history, and learning Swedish more profoundly. Also, a reunion party with my old school friends last summer made me dream of moving back to the US.&rdquo;</p><p>Right now, Debra Milton&rsquo;s last task is to write the NDPIA ten-year report. Through the years, as many as 740 PhD students and postdocs have enrolled as members.</p><p>&ldquo;What is interesting, is that most of our members are still doing research, not necessarily as assistant or associate professors but as staff scientists at universities or employed in companies. I hope that NDPIA has played a small role in their continued interest in research.&rdquo;</p><h2 id="info4" data-magellan-target="info4">Uncertain future for NDPIA</h2><p>Reflecting on the future, Debra Milton thinks that funding will be a challenging issue, and a new funding source is crucial. This past Spring, the Swedish Research Council opened a new call for funding for a research school within infection biology.</p><p>&ldquo;Hopefully, our NDPIA application will be a success and we can continue helping to strengthen the national and international network for infection biology in Sweden.&rdquo;</p><div class="mediaflowwrapper bildlink"><div class="bildText">&nbsp;</div></div>/en/news/ndpia--important-player-at-the-infection-biology-arena_11990087//en/news/reform-provided-better-access-to-health-care-in-ecuador_11990530/A significant improvement in the population's access to health care resulted from a major health care reform in Ecuador. At the same time, the fee for health care decreased for large groups of the population, but not for everyone. This is shown in a new thesis at Umeå University, Sweden. Tue, 01 Oct 2024 14:29:56 +0200<p>Over a ten-year period, between 2007 and 2017, the Government of Ecuador carried out a comprehensive reform of the health system with the aim of reducing socio-economic disparities in health care and achieving universal coverage of health care by all residents of the country.</p><p>In a thesis at the Department of Epidemiology and Global Health at Ume&aring; University, Edy Quizhpe has evaluated the effects of the reform.</p><p>A number of positive effects were observed: access to health care has improved significantly and social inequalities have decreased. We are now much closer to universal coverage of health care. This is a major improvement especially for socially vulnerable groups.</p><p>The evaluation also shows reduced expenses for health care fee for many households. At the same time, the reform has led to increased political involvement in health issues.</p><p>However, there are still problems. One is that the inequality between the indigenous population and the rest remains. Another is that people who are uninsured still have to pay high fees for health care. There is also concern about health care becoming a commodity and about the system's long-term financial sustainability.</p><div class="mediaflowwrapper bildlink halfwidthsquareright"><div class="bildImage"><picture><source srcset="/contentassets/eaca6302feb346cb81fd7c094004e6b9/edy_quizhpe3.jpg?format=webp&amp;mode=crop&amp;width=640 640w, /contentassets/eaca6302feb346cb81fd7c094004e6b9/edy_quizhpe3.jpg?format=webp&amp;mode=crop&amp;width=854 854w, /contentassets/eaca6302feb346cb81fd7c094004e6b9/edy_quizhpe3.jpg?format=webp&amp;mode=crop&amp;width=1280 1280w" type="image/webp" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"><source srcset="/contentassets/eaca6302feb346cb81fd7c094004e6b9/edy_quizhpe3.jpg?mode=crop&amp;width=640 640w, /contentassets/eaca6302feb346cb81fd7c094004e6b9/edy_quizhpe3.jpg?mode=crop&amp;width=854 854w, /contentassets/eaca6302feb346cb81fd7c094004e6b9/edy_quizhpe3.jpg?mode=crop&amp;width=1280 1280w" sizes="(max-width: 639px) 640px, (max-width: 854px) 854px, 1280px"></picture></div><div class="bildText"><p>Edy Quizhpe.</p><span class="bildPhotografer"><span class="photo">Image</span>Paola Floril</span></div></div><p>"For further development, it is important that health care's dependence on fees can be gradually reduced, as well as ensuring sufficient resources and achieving a balance between public and private interests so that public health is prioritised over economic gain," says Edy Quizhpe,</p><p><em>Edy Quizhpe is a doctor with many years of experience working in the health system in Ecuador.</em></p>/en/news/reform-provided-better-access-to-health-care-in-ecuador_11990530//en/news/arctic-centre-hosts-collaborative-event-for-the-arctic-five_11989340/On 25 September 2024, the Arctic Centre hosted a meet-up for all members of the Arctic Five at Umeå University. The meet-up took place at A Working Lab in Universum and was held to welcome the new Arctic Five Chairs, as well as introducing everyone to the Arctic Centre, and encourage collaboration.Fri, 27 Sep 2024 11:34:05 +0200<p>The meet-up consisted of presentations from the Arctic Centre staff and the attending members of the Arctic Five, as well as a joint lunch and interesting conversations. Arctic Centre&rsquo;s Director Keith Larson initiated with an introduction where he presented the Arctic Centre, the vision for it, and how the Arctic Centre can support the Arctic Five members. He mentioned that the goal for the Arctic Centre is to support the researchers, highlight their activities, and be a meeting place for cross-disciplinary collaboration.</p><p>&ndash; Our vision is to be a centre where inter- and transdisciplinary thinking, research and collaboration is the norm, Larson says.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="9ea7c5c2-31d3-406c-99f9-b9c52ad7397b" data-contentname="PIC A5 meet-up KL">{}</div><h2 id="info0" data-magellan-target="info0">Arctic Centre is a supporting resource</h2><p>After a lunch break and some conversations, the staff of the Arctic Centre presented themselves and what they can do for the Arctic Five members. The message was clear that the Arctic Centre is a supporting resource for the researchers, ready to help with promoting their research endeavours related to both the Arctic Five and the Arctic. It can be everything from organising a seminar or event, to help highlighting activities and research successes.</p><h2 id="info1" data-magellan-target="info1">Five newly appointed Arctic Five Chairs</h2><p>The Arctic Five has a wide range of members, from students, Doctoral students and established researchers who are Chairs, Fellows, and involved in different working groups. Earlier this year, the Arctic Five <a href="~/link/a3fa082c69f24f288e498ae4ddec6857.aspx">appointed five new Chairs</a> from Ume&aring; University. These five new Chairs are Danielle Wilde, Bj&ouml;rn Norlin, Daniel Metcalfe, Armando Perez Cueto and Niklas Eklund. One of the purposes of the Arctic Five meet-up was to welcome them to their new chairships.</p><p>The new Chairs all hope that their chairship will lead to stronger and larger networks, collaborations, and relations between the Arctic Five universities, as well as between the actors and stakeholders outside academia.</p><p>&ldquo;I hope that we can use this money and these two years to even more strengthen the networks that we already have, and to try to to be more active and do something more concrete within the research project&rdquo;, says Bj&ouml;rn Norlin, Associate professor of History and Education, and Arctic Five Chair.</p><div data-classid="36f4349b-8093-492b-b616-05d8964e4c89" data-contentguid="9725acfe-7a81-424e-94e8-839b5ccd80ea" data-contentname="Fakta A6">{}</div>/en/news/arctic-centre-hosts-collaborative-event-for-the-arctic-five_11989340/